摘要:
The present invention provides, inter alia, compounds of Formula (I) and pharmaceutically acceptable salts thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds and the uses of such compounds as a method for the treatment of a disease or condition selected from the group consisting of central nervous system disorders, cognitive disorders, schizophrenia, dementia and other disorders in a mammal. The present invention further provides compounds of Formula (Id) and pharmaceutically acceptable salts thereof as CYP3A4 selective inhibitors.
摘要:
The present invention relates neutralising epitopes of IL-17A and IL-17F and antibodies which bind those epitopes. The present invention also relates to the therapeutic uses of the antibody molecules and methods for producing them.
摘要:
Non-uniformity of a rotatable electrophotographic imaging component is compensated. The component has an intentional periodic variation that produces density variations in a test target. The angular position on the component of the intentional variation is correlated with the amount of an unintentional variation at several points to produce a non-uniformity map. An image signal with multiple regions of data is received. For each region, the angular position of the intentional variation in that region is determined, and the non-uniformity map is used to determine the correction required for the unintentional variation. The image data in the region are adjusted to compensate, and corresponding toner is deposited.
摘要:
Methods for determining an amount of toner in a target area are provided. In one method, the target area is illuminated with a first light from a first illumination position that is on a first side of a plane that is normal to the target area so that any toner particles in the target area direct a reflected portion of the first light to the first side and a light is sensed at a surface at a sensing position on the first side of the plane to which toner particles at the target area direct the reflected portion of the first light and a sensed light signal is generated that is indicative of the sensed light.
摘要:
A High-Density Cabinet (HDC) that houses standard rack-mountable electronic equipment in a high-density configuration that also protects the equipment from transient electrical-supply problems. The standard HDC configuration provides up to 7,200 Watts of power at 110V or 220V AC with a backup supply lasting 30 minutes. The rack used for the HDC is approximately 2′5″ wide, 7′4″ high and approximately 3′2″ deep. The batteries in the HDC are located in the base of the HDC; the UPSs are located at the bottom of the HDC on a hinged-tray. This equipment takes up the bottom six RUs of the HDC; leaving 36 RUs available for production electronic equipment. The HDC also uses DIN-Rail blocks, which allow the safe, accessible, and unobtrusive connection of approximately 72 AC power cords into 36 sets of DIN-Rail blocks, in a space about 18″ high by 4″ wide and 2″ deep.
摘要:
A personal care composition is disclosed comprising abrasive particles. The personal care composition may take a variety of forms such as a leave-on composition or an emulsion and/or may comprise one or more actives or agents.
摘要:
The invention describes a method and latching assembly for securing a replaceable unit in a carriage assembly of an image forming device. The latching assembly receives the replaceable unit in the carriage assembly. As the replaceable unit gets loaded in the carriage assembly, the latching assembly may automatically apply, using a power source in the image forming device, a force on the replaceable unit in a direction towards the carriage assembly until the replaceable unit is latched therein.
摘要:
A parallel power chuck for clamping two ends of a shaft or similar workpiece for machining using two centering mechanisms. The centering mechanisms independently operate from a single internal actuation mechanism and clamp each end of the shaft regardless of shaft size from end to end. The internal actuation mechanism further equalizes applied clamping force after compensating for size variation.
摘要:
A pneumatic tire 10 has a carcass ply 12 or plies 12, 14 with a locked tie-in construction and a wrap-around toeguard 18. Each wrap-around toeguard 18 is a non cord reinforced elastomeric unitary strip wound 360.degree. in a singular annular bead. The wrap-around toeguard cord reinforced unitary strip 18 can be formed of a single elastomeric composition having a shore hardness of greater than 40. Alternatively the wrap-around toeguard may additionally include an apex portion 29 and a chafer portion 27 along with the toeguard portion 28, each portion 27, 29 being co-extruded or otherwise hot formed and shaped with the toeguard portion 28 to form the unitary strip 18 and can have distinct elastomeric composition relative to the toeguard portion 28.
摘要:
A method is provided of determining the cause of artifacts in images produced by an electrophotographic (EP) printer. A reference image is printed and artifacts in it are detected. After printing normal images, a test image is printed and artifacts in it are detected. If a detected artifact in the test image does not correspond to a detected artifact in the reference image, a characteristic frequency spectrum of the artifact in the test image is determined. Run-out on rotatable imaging components is measured, and a characteristic frequency spectrum of each is determined. The test image spectrum is compared to each component spectrum to identify which component is causing the artifact.