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234 条记录 (耗时 0.03 秒)

    CUSTOMIZABLE FACILITY
    11.
    发明申请
    CUSTOMIZABLE FACILITY 有权

    公开(公告)号：US20220106800A1

    公开(公告)日：2022-04-07

    申请号：US17553283

    申请日：2021-12-16

    申请人： LONZA LTD

    发明人： Jonathan FORTIN ,  Lesley WOOD ,  Stefan WIDMER ,  Sandra CARBONNEAU ,  Alexander ZAHIRI

    IPC分类号： E04H1/00 ,  F24F3/167 ,  C12M1/12 ,  E04H5/02 ,  E04H5/00

    摘要： A customizable facility for manufacturing at least one product has at least one modular unit in communication with at least one central unit configured to provide utilities to the at least one modular unit. In some embodiments, the central unit(s) and modular unit(s) are positioned at least partially within a shell. Each modular unit can be a fermentation unit, a pre-viral unit, a post-viral unit, a utility space, a warehouse, a media buffer facility, an office, a personnel unit, or another unit. The modular units can be arranged to maximize a number of modular units within the shell while minimizing a footprint of the shell. A method of assembling a facility for manufacturing at least one product includes providing at least one central unit and providing at least one modular unit in communication with the central unit(s) such that utilities are provided by the central unit(s) to the modular unit(s).

    METHODS OF ASSAYING TROPOLONE
    14.
    发明申请
    METHODS OF ASSAYING TROPOLONE 有权

    公开(公告)号：US20210178289A1

    公开(公告)日：2021-06-17

    申请号：US16769842

    申请日：2018-12-04

    申请人： LONZA LTD

    发明人： Benjamin Alexander WILKES

    IPC分类号： B01D15/08 ,  C07K16/00 ,  C07C49/717

    摘要： Disclosed herein are methods useful for detecting and/or quantifying tropolone in samples, e.g., generated during the production of and in final formulations of a product, e.g., a recombinant protein, e.g., an antibody. Tropolone and derivatives thereof (cycloheptatriene ketones) are separated from a mixture by adding a partially or fully fluorinated alkyl or aryl (e.g. pentafluorophenyl-propyl), which (covalently) binds the tropolone-like compound. Then it is assayed via UV or tandem mass spectrometry. A reaction mixture of tropolone-like compounds and fluorinated alkyl or aryl is also disclosed.

    Filter moving device
    18.
    发明授权
    Filter moving device 有权

    公开(公告)号：US10919715B2

    公开(公告)日：2021-02-16

    申请号：US16345929

    申请日：2017-11-07

    申请人： Lonza Ltd.

    发明人： Danny Sugianto

    IPC分类号： B65G59/02 ,  B01D29/46 ,  B01D25/00 ,  B01D46/40 ,  B65G59/00 ,  B01D46/52

    摘要： A filter moving device is disclosed that is designed to lift and move a filter cartridge stack comprised of individual filter cartridges. The filter cartridge stack, for instance, may comprise a plurality of disk-shaped filter cartridges. The filter moving device is designed to be placed over the stack. The device includes lifting elements that engage the stack for removing the stack from a filter assembly and/or installing the stack in a filter assembly.