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公开(公告)号：US12280232B2
公开(公告)日：2025-04-22
申请号：US18227211
申请日：2023-07-27
Applicant: Becton, Dickinson and Company
Inventor： Yiping Ma , Siddarth Kamath Shevgoor
Abstract: A cap is configured to provide antimicrobial protection to a female luer port of an intravenous device. The cap distributes an antimicrobial solution within the intraluminal surfaces of the port when the cap is connected to the port. A cap may also be designed to distribute an antimicrobial solution around the exterior surfaces of the port. Once connected to a port, the cap can form a seal that minimizes the evaporation of the antimicrobial solution from within the lumen of a port. The cap can therefore provide antimicrobial protection against another device that is connected to the port once the cap is removed.
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公开(公告)号：USD1071157S1
公开(公告)日：2025-04-15
申请号：US29881358
申请日：2022-12-30
Applicant: Becton, Dickinson and Company
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公开(公告)号：US12270750B2
公开(公告)日：2025-04-08
申请号：US18641039
申请日：2024-04-19
Applicant: Becton, Dickinson and Company
Inventor： Joseph T. Trotter , Keegan Owsley , Jonathan Lin
IPC: G01N15/14 , B07C5/342 , B07C5/36 , G01N15/1434 , G01N15/149 , G06V10/70 , G06V20/69 , G16C20/20
Abstract: A cell sorting system that automatically generates a sorting strategy based on examples of target events provided by an operator. The target events can be selected using measurements ranging from traditional flow cytometry measurements to derived measurements that are computationally expensive to complex measurements such as images.
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公开(公告)号：US20250109427A1
公开(公告)日：2025-04-03
申请号：US18730043
申请日：2023-02-06
Applicant: Becton, Dickinson and Company
Inventor： Hye-Won Song , Dennis Edward Prosen
IPC: C12Q1/6806
Abstract: Disclosed herein include systems, methods, compositions, and kits for full-length whole transcriptome analysis (WTA). Some embodiments comprise 5′-based, 3′-based, and internal-based gene expression profiling. Immune repertoire profiling methods are also provided in some embodiments.
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公开(公告)号：US20250092458A1
公开(公告)日：2025-03-20
申请号：US18821342
申请日：2024-08-30
Applicant: Becton, Dickinson and Company
Inventor： Glenn P. Bartholomew , Jody Martin
IPC: C12Q1/6876 , B01L7/00
Abstract: Scaffolded chromophores for nucleic acid detection and systems, methods, and uses thereof are provided. Certain embodiments are directed to nucleic acid probes that include a nucleic acid that is complementary to a target sequence. The probe further includes a dye structure linked to a first end of the nucleic acid and includes a non-conjugated polymeric backbone with one or more donor fluorophores linked to the polymeric backbone and one or more acceptor fluorophores linked to the polymeric backbone, where the donor and acceptor fluorophores are in energy transfer relationship. Such probes can further include a quencher attached to a second end of the nucleic acid, where the quencher and one or more acceptor fluorophores are in an energy transfer relationship. Additional embodiments include a second nucleic acid probe including a second nucleic acid that is complementary to a different target sequence.
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Patent Agency Ranking
公开(公告)号：US20250090828A1
公开(公告)日：2025-03-20
申请号：US18900314
申请日：2024-09-27
Applicant: Becton, Dickinson and Company
Inventor： Jonathan Karl Burkholz , Huibin Liu , S. Ray Isaacson , Weston F. Harding , Lawrence J. Trainer
Abstract: The present invention relates to a cap for a medical connector. More specifically, the present invention related to an antimicrobial cap for placement over a connector, wherein various features of the antimicrobial cap maintain the connector in an antiseptic state.
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公开(公告)号：US20250084304A1
公开(公告)日：2025-03-13
申请号：US18957066
申请日：2024-11-22
Applicant: Becton, Dickinson and Company
Inventor： Yongchao Liang , Subodh Devendra Sonar
Abstract: Water-soluble fluorescent polymeric dyes and polymeric tandem dyes are provided. The polymeric dyes include a water solvated light harvesting multi-chromophore having a conjugated segment of aryl and/or heteroaryl co-monomers. The molar ratio of the co-monomers can be adjusted to provide beneficial technical properties, such as increased water solubility and improved absorption and emission spectra. For instance, the conjugated segment can have a first co-monomer substituted with a water-soluble group (WSG) and a second co-monomer, wherein the first co-monomer is in an amount that is equal or greater than the amount of the second co-monomer. multi-chromophore. The polymeric tandem dyes further include a signaling chromophore covalently linked to the multi-chromophore in energy-receiving proximity therewith. Also provided are aggregation-resistant labelled specific binding members that include the subject water-soluble polymeric dyes. Methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule in which the subject polymeric dyes find use are also provided. Systems and kits for practicing the subject methods are also provided.
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公开(公告)号：US12246157B2
公开(公告)日：2025-03-11
申请号：US16738928
申请日：2020-01-09
Applicant: Becton, Dickinson and Company
Inventor： Jonathan Karl Burkholz , Heena Dani , Megan Scherich , Derek Jewell
Abstract: A needleless access connector may include a body, which may include a proximal end configured to couple to an instrument delivery device and a distal end configured to couple to a peripheral intravenous catheter assembly. The needleless access connector may also include an accordion valve disposed within the body between the proximal end and the distal end. The accordion valve may include an accordion portion. In response to compression of the accordion portion and opening of the accordion valve, a straight pathway extending through the proximal end and the distal end may be exposed such that an instrument of the instrument delivery device may move distally from the proximal end to the distal end through the straight pathway without bending.
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公开(公告)号：US12246145B2
公开(公告)日：2025-03-11
申请号：US17339555
申请日：2021-06-04
Applicant: Becton, Dickinson and Company
Inventor： Weston F. Harding , Megan Scherich , Jonathan Karl Burkholz , Yiping Ma , John Lackey , Tyler Warner
Abstract: A catheter assembly may include a catheter adapter, a catheter, and a dressing to securely apply traction to the catheter where the catheter is disposed within a vasculature of a patient. The catheter adapter may include a proximal end, a distal end, and a lumen extending between the proximal end and the distal end. The catheter may extend from the distal end of the catheter adapter. The dressing may include a first section adjustably coupled to a second section. The first section may be configured to secure the catheter adapter and/or the catheter to the patient. The second section may be configured to be adjustably positioned relative to the first section to apply the traction to the catheter within the vasculature.
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公开(公告)号：US12245841B2
公开(公告)日：2025-03-11
申请号：US17949928
申请日：2022-09-21
Applicant: Becton, Dickinson and Company
Inventor： Yiping Ma , Azadeh Khanicheh
Abstract: A system to detect a position of a cannula may include a cannula, which may include a distal tip and an inner lumen. Also, the system may include an optical fiber, which may be disposed within the inner lumen of the cannula and may include a first end, a second end, and a U-shaped portion disposed between the first end and the second end. The U-shaped portion may be at least proximate the distal tip. Further, the system may include a light emitter, which may be coupled with the first end of the optical fiber, and a light receiver, which may be coupled with the second end of the optical fiber. Moreover, the system may include an electronic processor. The electronic processor may be coupled with the light receiver and configured to detect a decrease in an intensity of light received at the light receiver.
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