公开(公告)号：US20100137831A1

公开(公告)日：2010-06-03

申请号：US12597103

申请日：2008-04-23

Applicant: Izrail Tsals

Inventor： Izrail Tsals

IPC: A61M5/31

CPC classification number: A61M5/46 ,  A61M5/3243 ,  A61M5/3271 ,  A61M5/3287 ,  A61M5/425 ,  A61M2005/3247

Abstract: Devices and methods for intradermal (ID) administration of diagnostic and therapeutic agents, vaccines and other compounds into the dermal layer of the skin are disclosed. The devices and the methods simplify the ID injection process and increase the consistency of the placement of the needle tip in the dermal space close to the skin surface allowing for a shallow cannula placement in the dermis. Furthermore, the devices and methods broaden the number of sites suitable for ID injection and make the ID injection possible with limited training.

Abstract translation: 公开了将皮肤（ID）给予皮肤真皮层中的诊断和治疗剂，疫苗和其它化合物的装置和方法。 装置和方法简化了ID注射过程，并且增加了针尖靠近皮肤表面的皮肤空间中的放置位置的一致性，从而允许在真皮中放置浅插管。 此外，设备和方法扩大了适用于ID注入的站点数量，并且可以通过有限的培训进行ID注入。

公开(公告)号：US20060228369A1

公开(公告)日：2006-10-12

申请号：US11266496

申请日：2005-11-04

Applicant: Dexiang Chen

Inventor： Dexiang Chen

IPC: A61K39/00

CPC classification number: A61K39/39 ,  A61K2039/55505

Abstract: The present invention relates to the use of temperature protective agents to protect temperature sensitive vaccines. Such agents can be used to protect vaccines from degradation that results from exposure to freezing conditions or hot environments. Such agents can also be used to help reduce or prevent degradation or contamination in reconstituted vaccines. The temperature protective agent may include glycerin, polyethylene glycol or propylene glycol.

Abstract translation: 本发明涉及使用温度保护剂来保护感温疫苗。 这些药剂可用于保护疫苗免受由于暴露于冷冻条件或炎热环境而导致的降解。 此类试剂也可用于帮助减少或防止再造疫苗中的降解或污染。 温度保护剂可以包括甘油，聚乙二醇或丙二醇。

公开(公告)号：US20050025847A1

公开(公告)日：2005-02-03

申请号：US10786561

申请日：2004-02-26

Applicant: Florence Camus-Bablon ,  Lourens Zaneveld ,  Donald Waller

Inventor： Florence Camus-Bablon ,  Lourens Zaneveld ,  Donald Waller

IPC: A61F6/06 ,  A61F13/00 ,  A61F13/02 ,  A61K20060101 ,  A61K9/20 ,  A61K9/64 ,  A61K31/045 ,  A61K47/00 ,  A61K35/78

CPC classification number: A61K31/045 ,  A61K31/14 ,  A61K31/4412 ,  A61K31/737 ,  A61K31/765 ,  A61K31/795 ,  A61K36/28 ,  A61K45/06 ,  A61K2300/00

Abstract: The present invention is directed to microbicidal compositions and methods of use thereof for preventing the transmission of or treating sexually transmitted infections and/or common vaginal infections, while minimizing disruptions to vaginal ecology. The microbicidal compositions of the present invention comprise the microbicidal agent bisabolol. In a further embodiment of the present invention, the microbicidal agent may comprise a combination of bisabolol and Ciclopirox Olamine. These compositions are preferably encapsulated in the form of a foam, cream, wash, gel, suppository, ovule, ointment, film, tablet, foaming tablet, tampon, vaginal spray, or aerosol. The concentration of microbicidal agent will vary depending on the base or carrier. Preferably the concentration will fall within the parameters of approximately 0.01% to approximately 50% by weight, more preferably between approximately 0.01% to approximately 28%, and most preferably between approximately 0.05% and approximately 2%. In a preferred embodiment, the base or carrier is a gel and the microbicidal agent concentration will preferably range from approximately 0.01% to approximately 5% by weight, and more preferably from approximately 0.05% to approximately 2% by weight.

Abstract translation: 本发明涉及杀菌组合物及其使用方法，用于预防透过或治疗性传播感染和/或常见的阴道感染，同时最大限度地减少对阴道生态学的破坏。 本发明的杀微生物剂组合物包含杀微生物剂红没药醇。 在本发明的另一个实施方案中，杀微生物剂可以包含红没药醇和环吡酮奥胺的组合。 这些组合物优选以泡沫，乳膏，洗涤剂，凝胶剂，栓剂，胚珠，软膏，薄膜，片剂，发泡片剂，卫生棉条，阴道喷雾剂或气雾剂的形式包封。 杀菌剂的浓度将根据碱或载体而变化。 优选地，浓度将落入约0.01％至约50％重​​量，更优选约0.01％至约28％，最优选约0.05％至约2％的参数内。 在优选的实施方案中，碱或载体是凝胶，杀微生物剂浓度优选为约0.01重量％至约5重量％，更优选约0.05重量％至约2重量％。