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    SUBCUTANEOUS AND INTRADERMAL PATCH INFUSERS
    2.
    发明申请
    SUBCUTANEOUS AND INTRADERMAL PATCH INFUSERS 审中-公开
    婴幼儿和肛门输卵管

    公开(公告)号：US20140194854A1

    公开(公告)日：2014-07-10

    申请号：US14240902

    申请日：2012-08-23

    Applicant: Izrail Tsals

    Inventor： Izrail Tsals

    IPC: A61M5/158

    CPC classification number: A61M5/158 ,  A61M5/14248 ,  A61M5/1454 ,  A61M5/1456 ,  A61M2005/14256 ,  A61M2005/14513 ,  A61M2005/1581 ,  A61M2005/1585

    Abstract: The device infuses a compound subcutaneously or intradermally over an extended period of time. The delivery is from a conventional prefilled syringe with a staked cannula with the device adhered to the injection site and the syringe positioned substantially parallel to the injection site. The cannula is formed by a mechanism integral to the device to provide the cannula distal section substantially perpendicular to the syringe axis. The compound delivery is based on springs or other mechanisms. The approach offers a low cost mechanical system for the infusion of high volume, viscous compounds. The activation of the patch infuser required a few simple steps by the user. A single lever is used to trigger all device functions.

    Abstract translation: 该装置在长时间内皮下或皮内注入化合物。 该传送来自具有插入式插管的常规预充式注射器，该装置将该装置粘附到注射部位并且注射器基本上平行于注射部位定位。 套管由与装置成一体的机构形成，以提供基本上垂直于注射器轴线的套管远端部分。 复合输送是基于弹簧或其他机构。 该方法提供了低成本的机械系统，用于输注大体积，粘稠的化合物。 补丁infuser的激活需要用户简单的几个步骤。 单个杆用于触发所有设备功能。

    Automatic syringe
    4.
    发明授权
    Automatic syringe 有权
    自动注射器

    公开(公告)号：US06830560B1

    公开(公告)日：2004-12-14

    申请号：US09617340

    申请日：2000-07-17

    Applicant: Joseph Gross ,  Gilad Lavi ,  Izrail Tsals

    Inventor： Joseph Gross ,  Gilad Lavi ,  Izrail Tsals

    IPC: A61M3700

    CPC classification number: A61M5/2046 ,  A61M5/3202 ,  A61M5/3257 ,  A61M5/3272 ,  A61M5/46 ,  A61M2005/2013 ,  A61M2005/3247 ,  A61M2005/3267

    Abstract: A syringe comprises a barrel containing an internal cylindrical body containing a liquid and communicating with a delivery needle. The needle is covered before use by a removable sheath, and after the sheath is removed, the needle is concealed by a displaceable sleeve. In use the sleeve is pressed against the skin by applying pressure while holding the barrel. The sleeve is thereby retracted into the barrel allowing the needle to penetrate the skin. The movement of the sleeve also activates a gas generator which expels the liquid from the needle. When delivery is complete and the syringe is taken from the skin, a coil spring moves the sleeve back to the starting position again concealing the needle. The coil spring is torsionally biased before use and causes a rotational movement of the sleeve relative to the barrel when the sleeve moves into and out of the barrel. This rotational movement engages a locking mechanism which prevents further movement of the sleeve and thereby permanently conceals the needle.

    Abstract translation: 注射器包括容纳含有液体并与输送针连通的内部圆柱体的筒体。 针在使用前被可移除的护套覆盖，并且在护套被移除之后，针被可移位的套管隐藏。 在使用中，通过在保持桶的同时施加压力将套筒压靠在皮肤上。 因此套筒被缩回到镜筒中，允许针穿透皮肤。 套筒的运动还激活排出针头液体的气体发生器。 当输送完成并且从皮肤取出注射器时，螺旋弹簧将套筒移回到再次隐藏针的起始位置。 螺旋弹簧在使用前被扭转偏压，并且当套筒移入和移出筒体时，使套筒相对于筒体旋转运动。 该旋转运动接合锁定机构，该锁定机构防止套筒的进一步运动，从而永久地隐藏针头。

    Drug delivery systems and methods
    7.
    发明授权
    Drug delivery systems and methods 失效
    药物输送系统和方法

    公开(公告)号：US06478771B1

    公开(公告)日：2002-11-12

    申请号：US09439963

    申请日：1999-11-12

    Applicant: Gilad Lavi ,  Gil Yigal ,  Izrail Tsals ,  Joseph Gross

    Inventor： Gilad Lavi ,  Gil Yigal ,  Izrail Tsals ,  Joseph Gross

    IPC: A61M3700

    CPC classification number: A61J1/2089 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2017 ,  A61J1/2051 ,  A61J1/2058 ,  A61J1/2082 ,  A61M5/148 ,  A61M5/162 ,  A61M5/1782 ,  A61M5/19 ,  A61M5/2046 ,  A61M5/2053 ,  A61M5/2425 ,  A61M5/2448 ,  A61M5/3234 ,  A61M2005/14252 ,  A61M2005/1581 ,  A61M2005/3128 ,  A61M2005/3223 ,  A61M2205/215 ,  A61M2205/583

    Abstract: The present invention relates to a drug delivery device for mixing and delivering a drug by injection. The device includes a housing having a first port or opening therein that receives a first container that contains a fluid or powdered drug, for example a lyophilized drug. The housing can also include a second port or opening that receives a second container that contains a fluid to be mixed with the drug to form an injectable fluid. The device includes a manifold having a channel that fluidly connects the first and second containers. A penetrating membrane such as a needle is used to inject the drug into a patient which is in fluid communication with the first container. The needle is movable from a storage position in the housing to an injection position extending through the housing.

    Abstract translation: 本发明涉及通过注射混合和输送药物的药物递送装置。 该装置包括具有其中的第一端口或开口的壳体，其容纳包含流体或粉末状药物的第一容器，例如冻干药物。 壳体还可以包括接收第二容器的第二端口或开口，第二容器包含待与药物混合以形成可注射流体的流体。 该装置包括具有流体连接第一和第二容器的通道的歧管。 使用诸如针的穿透膜将药物注射到与第一容器流体连通的患者体内。 针可以从壳体中的存储位置移动到延伸穿过壳体的注射位置。

    Medicament conversion system
    8.
    发明授权
    Medicament conversion system 失效
    药物转化系统

    公开(公告)号：US5791466A

    公开(公告)日：1998-08-11

    申请号：US709486

    申请日：1996-09-06

    Applicant: Izrail Tsals

    Inventor： Izrail Tsals

    IPC: A61J1/05 ,  A61J1/00 ,  A61J1/06 ,  A61J1/20 ,  A61J3/00 ,  B65D25/08

    CPC classification number: A61J1/2089 ,  A61J1/062 ,  A61J1/201

    Abstract: A system for converting a medicament from a storage form to an administrable form comprises an evacuted medicament container, a container for a liquid, and means in the form of a hollow needle for establishing communication between said containers and thereby causing liquid to be drawn by suction from the liquid container to the medicament container. By establishing communication between an evacuated container and an unevacuated container, there is an instant, reliable and controlled addition of liquid to the medicament from the liquid container. The system has particular application to lyophilised medicaments.

    Abstract translation: 用于将药物从储存形式转化为可施用形式的系统包括抽空的药物容器，用于液体的容器和中空针形式的装置，用于建立所述容器之间的连通，从而使液体通过抽吸被拉伸 从液体容器到药物容器。 通过建立抽真空的容器和未消毒的容器之间的连通，从液体容器向药物中立即，可靠和可控地添加液体。 该系统特别适用于冻干药物。

    Variable permeability steering torque sensor
    10.
    发明授权
    Variable permeability steering torque sensor 失效
    可变磁导率转向扭矩传感器

    公开(公告)号：US4796463A

    公开(公告)日：1989-01-10

    申请号：US34535

    申请日：1987-04-06

    Applicant: Izrail Tsals ,  Ilya Feygin ,  William Marder

    Inventor： Izrail Tsals ,  Ilya Feygin ,  William Marder

    IPC: G01L3/10 ,  G01L5/22

    CPC classification number: G01L5/221 ,  G01L3/105

    Abstract: An electromagnetic torque sensor arrangement comprising a pair of magnetic circuits differentially responsive to the twist of a rotary shaft under load. Each magnetic circuit comprises a stator assembly, and at least one deflectable element disposed therein on a pair of pins which experience relative rotation in relation to the twist of the shaft. The relative rotation causes deflection of the deflectable elements in relation to the twist, and the resulting variation in the permeability of the magnetic circuits is detected as a measure of the applied torque.

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