公开(公告)号：US20140046339A1

公开(公告)日：2014-02-13

申请号：US14054301

申请日：2013-10-15

Applicant: P Tech, LLC

Inventor： Peter M. Bonuttti

IPC: A61B17/22

CPC classification number: A61B17/22012 ,  A61B5/055 ,  A61B8/00 ,  A61B17/22004 ,  A61B2017/00004 ,  A61B2017/00022 ,  A61B2017/00075 ,  A61B2017/00106 ,  A61B2017/00199 ,  A61B2017/22015 ,  A61F2250/0001 ,  A61H1/008 ,  A61H23/00 ,  A61H2023/002 ,  A61H2201/02 ,  A61H2201/0207 ,  A61H2201/10 ,  A61H2201/105 ,  A61H2201/5012 ,  A61N1/3787 ,  A61N1/40 ,  A61N2/002 ,  A61N2/02 ,  A61N7/00 ,  A61N2007/0052

Abstract: The present disclosure provides a device for transmitting focused acoustic energy from a tissue surface of a face of a user to at least one sinus. The device includes a power supply; a signal source configured to provide a waveform of at least 20 kHz that is configured to increase a flow of fluid from the at least one sinus; and a transducer connected to the power supply and the signal source, the transducer configured to contact a medium applied to the tissue surface of the face and transmit the waveform through the medium and the tissue surface of the face to the at least one sinus.

Abstract translation: 本公开提供了一种用于将聚焦的声能从用户的脸部的组织表面传输到至少一个窦的装置。 该装置包括电源; 信号源，被配置为提供至少20kHz的波形，其被配置为增加来自所述至少一个窦的流体流; 以及连接到所述电源和所述信号源的换能器，所述换能器被配置为接触施加到所述面部的组织表面的介质，并且将所述波形通过所述介质和所述面部的组织表面传输到所述至少一个窦。

公开(公告)号：US08641622B2

公开(公告)日：2014-02-04

申请号：US13230498

申请日：2011-09-12

Applicant: Peter G. Barthe ,  Michael H. Slayton ,  Inder Raj S. Makin

Inventor： Peter G. Barthe ,  Michael H. Slayton ,  Inder Raj S. Makin

IPC: A61B8/00

CPC classification number: A61N7/02 ,  A61B5/682 ,  A61B5/6842 ,  A61B8/08 ,  A61B8/0858 ,  A61B8/12 ,  A61B8/13 ,  A61B8/4209 ,  A61B8/4281 ,  A61B8/4455 ,  A61B8/4483 ,  A61B8/461 ,  A61B8/483 ,  A61B8/546 ,  A61B17/320068 ,  A61H23/0245 ,  A61H2201/5007 ,  A61N7/00 ,  A61N2007/0008 ,  A61N2007/0034 ,  A61N2007/0052 ,  A61N2007/027 ,  G01S15/8909

Abstract: A method and system for ultrasound treatment of photoaged tissue are provided. An exemplary method and system are configured for first, ultrasound imaging of the region of interest for localization of the treatment area, second, delivery of ultrasound energy at a depth and pattern to achieve the desired therapeutic effects, and third to monitor the treatment area during and after therapy to assess the results and/or provide feedback. The exemplary treatment method and system can be configured for producing arrays of sub-millimeter and larger zones of thermal ablation to treat the epidermal, superficial dermal, mid-dermal and deep dermal components of photoaged tissue.

Abstract translation: 提供了一种用于光电组织超声处理的方法和系统。 一种示例性方法和系统被配置用于首先对感兴趣区域的超声成像进行治疗区域的定位，其次，以深度和图案递送超声能量以获得期望的治疗效果，第三，监测治疗区域的治疗区域 并在治疗后评估结果和/或提供反馈。 可以将示例性治疗方法和系统配置用于产生亚毫米和更大的热消融区域阵列，以治疗光化组织的表皮，浅表皮肤，中间皮肤和深层真皮成分。

公开(公告)号：US20130338544A1

公开(公告)日：2013-12-19

申请号：US13902644

申请日：2013-05-24

Applicant: David W. Newell

Inventor： David W. Newell

IPC: A61N7/02

CPC classification number: A61N7/02 ,  A61B8/06 ,  A61B8/0808 ,  A61B8/488 ,  A61B17/22004 ,  A61B90/10 ,  A61N7/00 ,  A61N2007/0021 ,  A61N2007/0052 ,  A61N2007/0078

Abstract: Methods for treating a human patient having a subarachnoid hematoma, such as to prevent cerebral vasospasm or to reduce the severity of cerebral vasospasm in the patient, and associated devices, systems, and methods are disclosed herein. In a particular embodiment, a thrombolytic agent is introduced extravascularly into a subarachnoid region including the hematoma. A headset configured for hands-free delivery of transcranial ultrasound energy is connected to the patient and used to deliver ultrasound energy to the subarachnoid region to enhance the thrombolytic effect of the thrombolytic agent. The type and/or dosage of the thrombolytic agent can be selected based on the enhanced thrombolytic effect. For example, the enhanced thrombolytic effect can allow the therapeutically effective use of less aggressive thrombolytic agents and/or lower dosages of thrombolytic agents. In some cases, this can reduce the clinical probability of additional cerebral hemorrhage.

Abstract translation: 本文公开了用于治疗具有蛛网膜下血肿的人患者的方法，例如用于预防脑血管痉挛或降低患者脑血管痉挛的严重性，以及相关的装置，系统和方法。 在一个具体的实施方案中，血栓溶解剂引入包括血肿的蛛网膜下区域。 被配置为用于免提递送经颅超声能量的耳机连接到患者，并用于将超声能量输送到蛛网膜下区域以增强溶栓剂的溶栓作用。 溶血栓剂的类型和/或剂量可以基于增强的血栓溶解作用来选择。 例如，增强的血栓溶解作用可以允许治疗有效地使用较少侵袭性溶栓剂和/或较低剂量的溶栓剂。 在某些情况下，这可以降低额外的脑出血的临床概率。

公开(公告)号：US20130281853A1

公开(公告)日：2013-10-24

申请号：US13924376

申请日：2013-06-21

Applicant: Guided Therapy Systems, LLC

Inventor： Michael H. Slayton ,  Peter G. Barthe ,  Inder Raj S. Makin ,  Brian D. O'Connor

IPC: A61N7/02 ,  A61B8/13

CPC classification number: A61N7/02 ,  A61B5/682 ,  A61B5/6842 ,  A61B8/08 ,  A61B8/0858 ,  A61B8/12 ,  A61B8/13 ,  A61B8/4209 ,  A61B8/4281 ,  A61B8/4455 ,  A61B8/4483 ,  A61B8/461 ,  A61B8/483 ,  A61B8/546 ,  A61B17/320068 ,  A61H23/0245 ,  A61H2201/5007 ,  A61N7/00 ,  A61N2007/0008 ,  A61N2007/0034 ,  A61N2007/0052 ,  A61N2007/027 ,  G01S15/8909

Abstract: Systems and methods for noninvasive tissue tightening are disclosed. Thermal treatment of tissues such as superficial muscular aponeurosis system (SMAS) tissue, muscle, adipose tissue, dermal tissue, and combinations thereof are described. In one aspect, a system is configured for treating tissue through delivery of ultrasound energy at a depth, distribution, temperature, and energy level to achieve a desired cosmetic effect.

Abstract translation: 公开了用于非侵入性组织紧固的系统和方法。 描述了诸如表面肌腱膜系统（SMAS）组织，肌肉，脂肪组织，真皮组织及其组合的组织的热处理。 在一个方面，一种系统被配置用于通过在深度，分布，温度和能量水平传递超声能量来治疗组织以实现期望的美容效果。

公开(公告)号：US08517962B2

公开(公告)日：2013-08-27

申请号：US13048830

申请日：2011-03-15

Applicant: Michael Gertner ,  David Perozek ,  Arash Sabet ,  Jimin Zhang

Inventor： Michael Gertner ,  David Perozek ,  Arash Sabet ,  Jimin Zhang

IPC: A61B5/05

CPC classification number: A61N7/00 ,  A61B5/0225 ,  A61B5/0263 ,  A61B5/055 ,  A61B5/061 ,  A61B5/201 ,  A61B5/412 ,  A61B5/4528 ,  A61B5/4839 ,  A61B5/489 ,  A61B5/4893 ,  A61B6/03 ,  A61B6/032 ,  A61B6/037 ,  A61B6/487 ,  A61B6/504 ,  A61B6/506 ,  A61B8/00 ,  A61B8/06 ,  A61B8/08 ,  A61B8/0841 ,  A61B8/0891 ,  A61B8/14 ,  A61B8/4245 ,  A61B8/485 ,  A61B8/488 ,  A61B90/37 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2090/374 ,  A61B2090/3762 ,  A61B2090/378 ,  A61N5/0601 ,  A61N5/062 ,  A61N5/0622 ,  A61N7/02 ,  A61N2005/063 ,  A61N2007/0026 ,  A61N2007/003 ,  A61N2007/0052 ,  A61N2007/0078

Abstract: A system for treatment includes a focused ultrasound energy source for placement outside a patient, wherein the focused ultrasound energy source is configured to deliver ultrasound energy towards a blood vessel with a surrounding nerve that is a part of an autonomic nervous system inside the patient, and wherein the focused ultrasound energy source is configured to deliver the ultrasound energy from outside the patient to the nerve located inside the patient to treat the nerve.

Abstract translation: 一种用于治疗的系统包括用于放置在患者外部的聚焦超声能量源，其中所述聚焦超声能量被配置为将周围神经作为患者内部的自主神经系统的一部分向血管递送超声能量，以及 其中所述聚焦超声能量源被配置为将超声能量从患者外部递送到位于患者内部的神经以治疗神经。

公开(公告)号：US08506486B2

公开(公告)日：2013-08-13

申请号：US13679430

申请日：2012-11-16

Applicant: Guided Therapy Systems, LLC

Inventor： Michael H. Slayton ,  Peter G. Barthe ,  Inder Raj S. Makin ,  Brian D. O'Connor

IPC: A61B7/02

CPC classification number: A61N7/02 ,  A61B5/682 ,  A61B5/6842 ,  A61B8/08 ,  A61B8/0858 ,  A61B8/12 ,  A61B8/13 ,  A61B8/4209 ,  A61B8/4281 ,  A61B8/4455 ,  A61B8/4483 ,  A61B8/461 ,  A61B8/483 ,  A61B8/546 ,  A61B17/320068 ,  A61H23/0245 ,  A61H2201/5007 ,  A61N7/00 ,  A61N2007/0008 ,  A61N2007/0034 ,  A61N2007/0052 ,  A61N2007/027 ,  G01S15/8909

Abstract: A method and system for noninvasive face lifts and tissue tightening are disclosed. The method and treatment system are configured for thermal treatment of Superficial Muscular Aponeurosis System (SMAS) tissue, muscular fascia, or both. In one embodiment, a cosmetic system is configured for treating the SMAS and/or muscular fasica through delivery of ultrasound energy at a depth, distribution, timing, and energy level to achieve the desired therapeutic effect.

Abstract translation: 公开了一种用于无创面部提升和组织紧固的方法和系统。 该方法和治疗系统被配置用于表面肌肉腱膜系统（SMAS）组织，肌肉筋膜或两者的热处理。 在一个实施例中，化妆品系统被配置用于通过在深度，分布，时间和能量水平传递超声能量来治疗SMAS和/或肌肉筋膜，以达到期望的治​​疗效果。

公开(公告)号：US08366622B2

公开(公告)日：2013-02-05

申请号：US13444336

申请日：2012-04-11

Applicant: Michael H. Slayton ,  Peter G. Barthe ,  Inder Raj S. Makin ,  Brian D. O'Connor

Inventor： Michael H. Slayton ,  Peter G. Barthe ,  Inder Raj S. Makin ,  Brian D. O'Connor

IPC: A61B7/02

CPC classification number: A61N7/02 ,  A61B5/682 ,  A61B5/6842 ,  A61B8/08 ,  A61B8/0858 ,  A61B8/12 ,  A61B8/13 ,  A61B8/4209 ,  A61B8/4281 ,  A61B8/4455 ,  A61B8/4483 ,  A61B8/461 ,  A61B8/483 ,  A61B8/546 ,  A61B17/320068 ,  A61H23/0245 ,  A61H2201/5007 ,  A61N7/00 ,  A61N2007/0008 ,  A61N2007/0034 ,  A61N2007/0052 ,  A61N2007/027 ,  G01S15/8909

Abstract: A method and system for noninvasive face lifts and deep tissue tightening are disclosed. An exemplary method and treatment system are configured for the imaging, monitoring, and thermal injury to treat the SMAS region. In accordance with an exemplary embodiment, the exemplary method and system are configured for treating the SMAS region by first, imaging of the region of interest for localization of the treatment area and surrounding structures, second, delivery of ultrasound energy at a depth, distribution, timing, and energy level to achieve the desired therapeutic effect, and third to monitor the treatment area before, during, and after therapy to plan and assess the results and/or provide feedback.

Abstract translation: 公开了一种用于无创面部提升和深层组织紧固的方法和系统。 配置了用于成像，监测和热损伤以处理SMAS区域的示例性方法和处理系统。 根据示例性实施例，示例性方法和系统被配置为通过首先对感兴趣区域进行成像以对治疗区域和周围结构进行定位来处理SMAS区域;其次，在深度，分布处输送超声能量， 时间和能量水平，以达到预期的治疗效果，第三是监测治疗前，治疗期间和治疗后的治疗区域，以计划和评估结果和/或提供反馈。

公开(公告)号：US20130018268A1

公开(公告)日：2013-01-17

申请号：US13546871

申请日：2012-07-11

Applicant: Laust G. Pedersen ,  Bobby Purkait

Inventor： Laust G. Pedersen ,  Bobby Purkait

IPC: A61B8/06

CPC classification number: A61N7/02 ,  A61B8/4254 ,  A61N2007/0052 ,  A61N2007/0065 ,  A61N2007/0078 ,  A61N2007/0095

Abstract: Scanning speed detection for freehand high frequency ultrasound transducers using a multiple element moving array transducer using a pair of elements as a Doppler scanning speed detector. Various aspects of the invention are disclosed.

Abstract translation: 使用多元素作为多普勒扫描速度检测器使用多元素移动阵列传感器的徒手高频超声换能器的扫描速度检测。 公开了本发明的各个方面。

公开(公告)号：US20120123243A1

公开(公告)日：2012-05-17

申请号：US13295182

申请日：2011-11-14

Applicant: Roger Hastings

Inventor： Roger Hastings

IPC: A61B5/055 ,  A61B8/00 ,  A61B18/16

CPC classification number: A61B34/20 ,  A61B6/032 ,  A61B8/0841 ,  A61B8/12 ,  A61B8/445 ,  A61B8/4488 ,  A61B17/2202 ,  A61B90/39 ,  A61B2017/00106 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2034/2051 ,  A61B2034/2063 ,  A61B2090/378 ,  A61B2090/3788 ,  A61B2090/3929 ,  A61B2090/3958 ,  A61B2090/3966 ,  A61N7/02 ,  A61N2005/1051 ,  A61N2005/1058 ,  A61N2007/003 ,  A61N2007/0052

Abstract: An in vivo apparatus includes a flexible shaft having a proximal end, a distal end, and a length sufficient to access a patient's renal artery relative to a percutaneous access location. An energy guide apparatus is provided at the distal end of the shaft and dimensioned for deployment within the renal artery. An ex vivo apparatus includes an arrangement configured to localize the energy guide apparatus within the renal artery, and an energy source configured to direct ablative energy to target tissue located a predetermined distance from the localized energy guide apparatus. The target tissue includes perivascular renal nerve tissue adjacent the renal artery.

Abstract translation: 体内装置包括柔性轴，其具有近端，远端和足以相对于经皮进入位置进入患者肾动脉的长度。 能量引导装置设置在轴的远端并且被设计成用于展开在肾动脉内。 离体装置包括被配置成使肾动脉内的能量引导装置定位的装置，以及被配置为将烧蚀能量定向到距离局部能量引导装置预定距离的目标组织的能量源。 靶组织包括邻近肾动脉的血管周围肾神经组织。

公开(公告)号：US20120065492A1

公开(公告)日：2012-03-15

申请号：US13048830

申请日：2011-03-15

Applicant: Michael Gertner ,  David Perozek ,  Arash Sabet ,  Jimin Zhang

Inventor： Michael Gertner ,  David Perozek ,  Arash Sabet ,  Jimin Zhang

IPC: A61B5/055 ,  A61B8/00 ,  A61B5/05 ,  A61N7/00

CPC classification number: A61N7/00 ,  A61B5/0225 ,  A61B5/0263 ,  A61B5/055 ,  A61B5/061 ,  A61B5/201 ,  A61B5/412 ,  A61B5/4528 ,  A61B5/4839 ,  A61B5/489 ,  A61B5/4893 ,  A61B6/03 ,  A61B6/032 ,  A61B6/037 ,  A61B6/487 ,  A61B6/504 ,  A61B6/506 ,  A61B8/00 ,  A61B8/06 ,  A61B8/08 ,  A61B8/0841 ,  A61B8/0891 ,  A61B8/14 ,  A61B8/4245 ,  A61B8/485 ,  A61B8/488 ,  A61B90/37 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2090/374 ,  A61B2090/3762 ,  A61B2090/378 ,  A61N5/0601 ,  A61N5/062 ,  A61N5/0622 ,  A61N7/02 ,  A61N2005/063 ,  A61N2007/0026 ,  A61N2007/003 ,  A61N2007/0052 ,  A61N2007/0078

Abstract: A system for treatment includes a focused ultrasound energy source for placement outside a patient, wherein the focused ultrasound energy source is configured to deliver ultrasound energy towards a blood vessel with a surrounding nerve that is a part of an autonomic nervous system inside the patient, and wherein the focused ultrasound energy source is configured to deliver the ultrasound energy from outside the patient to the nerve located inside the patient to treat the nerve.

Abstract translation: 一种用于治疗的系统包括用于放置在患者外部的聚焦超声能量源，其中所述聚焦超声能量被配置为将周围神经作为患者内部的自主神经系统的一部分向血管递送超声能量，以及 其中所述聚焦超声能量源被配置为将超声能量从患者外部递送到位于患者内部的神经以治疗神经。