公开(公告)号：US12082912B2

公开(公告)日：2024-09-10

申请号：US17508484

申请日：2021-10-22

Applicant: LightLab Imaging, Inc.

Inventor： Joseph M. Schmitt ,  Joel M. Friedman ,  Christopher Petroff ,  Amr Elbasiony

IPC: A61B5/02 ,  A61B5/00

CPC classification number: A61B5/02007 ,  A61B5/0066 ,  A61B5/0073 ,  A61B5/0084

Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

公开(公告)号：US20240057870A1

公开(公告)日：2024-02-22

申请号：US18385462

申请日：2023-10-31

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath ,  Mark Hoeveler

IPC: A61B5/00 ,  G06T7/13 ,  G06T7/00 ,  G16H30/40 ,  A61B34/00 ,  G06V10/82 ,  G16H40/63 ,  G06V10/764 ,  A61B34/10 ,  G06F3/0484 ,  G06T7/62 ,  G16H30/20 ,  G16H40/40

CPC classification number: A61B5/0066 ,  G06T7/13 ,  G06T7/0012 ,  G16H30/40 ,  A61B34/25 ,  G06V10/82 ,  G16H40/63 ,  G06V10/764 ,  A61B34/10 ,  G06F3/0484 ,  G06T7/62 ,  G16H30/20 ,  G16H40/40 ,  A61B2034/108 ,  G06T2207/30101 ,  A61F2/958

Abstract: In part, the disclosure relates to method of displaying a representation of an artery. The method may include storing an intravascular image dataset in a memory device of a diagnostic imaging system, the intravascular image dataset generated in response to intravascular imaging of a segment of an artery; automatically detecting lumen boundary of the segment on a per frame basis; automatically detecting EEL and displaying a stent sizing workflow. In part, the disclosure also relates to automatically detecting one or more regions of calcium relative to lumen boundary of the segment; calculating an angular or circumferential measurement of detected calcium for one or more frames; calculating a calcium thickness of detected calcium for one or more frames; and displaying the calcium thickness and the angular or circumferential measurement of detected calcium for a first frame of the one or more frames.

公开(公告)号：US20240046476A1

公开(公告)日：2024-02-08

申请号：US18378199

申请日：2023-10-10

Applicant: LightLab Imaging, Inc.

Inventor： Gregory Patrick Amis ,  Ajay Gopinath ,  Mark Hoeveler

IPC: G06T7/00 ,  G06T7/38 ,  G16H50/50 ,  G16H50/30 ,  G16H30/40 ,  A61B5/02 ,  A61B5/00 ,  G06T11/00

CPC classification number: G06T7/0016 ,  G06T7/38 ,  G16H50/50 ,  G16H50/30 ,  G16H30/40 ,  A61B5/02007 ,  A61B5/7264 ,  A61B5/7275 ,  A61B5/743 ,  G06T11/008 ,  G06T2207/20081 ,  G06T2207/30104

Abstract: The present disclosure provides systems and methods to receiving OCT or IVUS image data frames to output one or more representations of a blood vessel segment. The image data frames may be stretched and/or aligned using various windows or bins or alignment features. Arterial features, such as the calcium burden, may be detected in each of the image data frames. The arterial features may be scored. The score may be a stent under-expansion risk. The representation may include an indication of the arterial features and their respective score. The indication may be a color coded indication.

公开(公告)号：US11892291B2

公开(公告)日：2024-02-06

申请号：US17666726

申请日：2022-02-08

Applicant: LightLab Imaging, Inc.

Inventor： Chih-Hao Liu ,  Steven M. Stromski

IPC: G01B9/02 ,  G01B9/02091 ,  G01B9/02055

CPC classification number: G01B9/02091 ,  G01B9/02064 ,  G01B9/02084 ,  G01B2210/58

Abstract: Aspects of the disclosure relate to systems, methods, and algorithms to perform wavenumber linearization and dispersion correction in optical systems without the need for hardware modifications, empirical adjustments, precise mirror alignment, and which can be conducted at low computational costs and in real-time. A one-time calibration process can generate spectra or calibration criteria, including wavenumber-linearization criteria, dispersion correction, and spectral flattening spectra, which can be used to correct an optical coherence tomogram in real time.

公开(公告)号：US11883107B2

公开(公告)日：2024-01-30

申请号：US15718835

申请日：2017-09-28

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath

IPC: A61B34/10 ,  A61B8/12 ,  A61B8/08 ,  A61B8/00 ,  A61B5/00 ,  A61B8/06 ,  A61B6/00 ,  A61B5/107 ,  A61B34/00 ,  G16H50/50 ,  G16H50/30 ,  G06N20/00 ,  G16H20/40 ,  A61F2/82

CPC classification number: A61B34/10 ,  A61B5/0084 ,  A61B8/06 ,  A61B8/0891 ,  A61B8/12 ,  A61B8/463 ,  A61B8/466 ,  A61B8/5223 ,  G16H50/30 ,  G16H50/50 ,  A61B5/0066 ,  A61B5/107 ,  A61B6/504 ,  A61B34/25 ,  A61B2034/104 ,  A61B2034/105 ,  A61B2034/108 ,  A61F2/82 ,  A61F2240/001 ,  G06N20/00 ,  G16H20/40

Abstract: In part, the disclosure relates to determining a stent deployment location and other parameters using blood vessel data. Stent deployment can be planned such that the amount of blood flow restored from stenting relative to an unstented vessel increases one or more metrics. An end user can specify one or more stent lengths, including a range of stent lengths. In turn, diagnostic tools can generate candidate virtual stents having lengths within the specified range suitable for placement relative to a vessel representation. Blood vessel distance values such as blood vessel diameter, radius, area values, chord values, or other cross-sectional, etc. its length are used to identify stent landing zones. These tools can use or supplement angiography data and/or be co-registered therewith. Optical imaging, ultrasound, angiography or other imaging modalities are used to generate the blood vessel data.

公开(公告)号：US20230414314A1

公开(公告)日：2023-12-28

申请号：US18243924

申请日：2023-09-08

Applicant: LightLab Imaging, Inc.

Inventor： James Booker ,  David Ellman ,  Douglas Tatosian ,  Charles Milne

IPC: A61B90/00 ,  A61B5/00

CPC classification number: A61B90/39 ,  A61B5/0084 ,  A61B5/0066 ,  A61B2090/3966

Abstract: In one embodiment, the disclosure relates to a probe that a cylindrical marker band defining an inner surface, an outer surface, a first end and a second end and having a band length, the inner surface defining a marker band bore, the cylindrical marker band includes a radiopaque material; a molded unitary lens defining an elongate optical fiber receiving section having a fiber section length and a beam directing surface, wherein the fiber section length and the band length overlap along an overlap distance; and an optical fiber, wherein a first section of the optical fiber is disposed in the optical fiber receiving section, wherein a portion of the first section of the optical fiber is disposed within the marker band bore.

公开(公告)号：US11819309B2

公开(公告)日：2023-11-21

申请号：US16821877

申请日：2020-03-17

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath ,  Mark Hoeveler

IPC: G06F3/048 ,  A61B5/00 ,  A61B34/10 ,  A61B34/00 ,  G06T7/62 ,  G06T7/13 ,  G16H30/20 ,  G16H30/40 ,  G16H40/40 ,  G16H40/63 ,  G06F3/0484 ,  G06T7/00 ,  G06V10/764 ,  G06V10/82 ,  A61F2/958

CPC classification number: A61B5/0066 ,  A61B34/10 ,  A61B34/25 ,  G06F3/0484 ,  G06T7/0012 ,  G06T7/13 ,  G06T7/62 ,  G06V10/764 ,  G06V10/82 ,  G16H30/20 ,  G16H30/40 ,  G16H40/40 ,  G16H40/63 ,  A61B2034/107 ,  A61B2034/108 ,  A61F2/958 ,  G06T2200/24 ,  G06T2207/30052 ,  G06T2207/30101 ,  G06V2201/03

Abstract: In part, the disclosure relates to method of displaying a representation of an artery. The method may include storing an intravascular image dataset in a memory device of a diagnostic imaging system, the intravascular image dataset generated in response to intravascular imaging of a segment of an artery; automatically detecting lumen boundary of the segment on a per frame basis; automatically detecting EEL and displaying a stent sizing workflow. In part, the disclosure also relates to automatically detecting one or more regions of calcium relative to lumen boundary of the segment; calculating an angular or circumferential measurement of detected calcium for one or more frames; calculating a calcium thickness of detected calcium for one or more frames; and displaying the calcium thickness and the angular or circumferential measurement of detected calcium for a first frame of the one or more frames.

公开(公告)号：US11793462B2

公开(公告)日：2023-10-24

申请号：US15913300

申请日：2018-03-06

Applicant: LightLab Imaging, Inc.

Inventor： Joseph M. Schmitt ,  Chenyang Xu

IPC: A61B5/00

CPC classification number: A61B5/6852 ,  A61B5/0066 ,  A61B5/7264

Abstract: A method and apparatus for determining properties of a tissue or tissues imaged by optical coherence tomography (OCT). In one embodiment the backscatter and attenuation of the OCT optical beam is measured and based on these measurements and indicium such as color is assigned for each portion of the image corresponding to the specific value of the backscatter and attenuation for that portion. The image is then displayed with the indicia and a user can then determine the tissue characteristics. In an alternative embodiment the tissue characteristics is classified automatically by a program given the combination of backscatter and attenuation values.

公开(公告)号：US20230306620A1

公开(公告)日：2023-09-28

申请号：US18125520

申请日：2023-03-23

Applicant: LightLab Imaging, Inc.

Inventor： Angela Zhang ,  Shimin Li ,  Robert Steinbrecher ,  Jack Fince ,  Paul Gervasio

IPC: G06T7/33 ,  G06T3/40 ,  G06T3/20

CPC classification number: G06T7/337 ,  G06T3/40 ,  G06T3/20 ,  G06T2207/30101 ,  G06T2207/20092 ,  G06T2207/10121 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10101 ,  G06T2207/10132 ,  G06T2207/10108 ,  G06T2207/20212

Abstract: The disclosure relates to methods of providing live x-ray images such as fluoroscopic images in combination with reference information co-registered angiography frames that are motion corrected in real time. In part, the disclosure describes an improvement on the existing workflow where the user must remember where the vessel features from OCT are and use a reference frame to estimate the location of desired stent placement. Disclosed herein are methods to correlate the live imaging feed and the reference angiography image such that the user may dynamically zoom and pan the live imaging feed and the reference angiography image.

公开(公告)号：US20230280153A1

公开(公告)日：2023-09-07

申请号：US18177477

申请日：2023-03-02

Applicant: LightLab Imaging, Inc.

Inventor： Steven M. Stromski ,  Chih-Hao Liu

IPC: G01B9/02091 ,  G01B9/02055 ,  G01B9/02015

CPC classification number: G01B9/02091 ,  G01B9/02055 ,  G01B9/02015

Abstract: Aspects of the disclosure provide for automated self-inspection by an OCT imaging engine or device, to identify and resolve failures or inefficiencies in the hardware and/or software of the system or device during imaging. An OCT imaging engine can include a catheter connection check system for checking the quality of a physical connection point between a catheter and other components of an OCT imaging device or system. In some examples, the OCT imaging engine includes a self-inspection engine implemented to perform routine self-inspection by using a reference reflector internal to the OCT imaging engine to generate system performance data. The OCT imaging engine can use the system performance data to periodically search for and resolve failures or inefficiencies in the system. The OCT imaging engine can perform a self-calibration process to perform k-linearization and/or correct for chromatic dispersion using mirror measurements collected from an internal reference reflector.