公开(公告)号：US11058308B2

公开(公告)日：2021-07-13

申请号：US16206033

申请日：2018-11-30

Applicant: LightLab Imaging, Inc.

Inventor： Joseph M. Schmitt ,  Christopher Petroff

IPC: A61B5/00 ,  A61B5/0215 ,  A61B5/02

Abstract: An optical coherence tomography system and method with integrated pressure measurement. In one embodiment the system includes an interferometer including: a wavelength swept laser; a source arm in communication with the wavelength swept laser; a reference arm in communication with a reference reflector, a first photodetector having a signal output; a detector arm in communication with the first photodetector, a probe interlace; a sample arm in communication with a first optical connector of the probe interface; an acquisition and display system comprising: an A/D converter having a signal input in communication with the first photodetector signal output and a signal output; a processor system in communication with the A/D converter signal output; and a display in communication with the processor system; and a probe comprising a pressure sensor and configured for connection to the first optical connector of the probe interface, wherein the pressure transducer comprises an optical pressure transducer.

公开(公告)号：US20210085275A1

公开(公告)日：2021-03-25

申请号：US17025473

申请日：2020-09-18

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath

IPC: A61B6/00 ,  A61B5/0402 ,  A61B90/00

Abstract: Aspects of the disclosure relate to the combination and display of both live and non-live patient images. The features described include collecting angiographic image data, and correlating angiographic image frames to time-varying data relating to the patient's heart cycle. This time-varying data may then be compared with the patient's live heart cycle data so that the collected angiographic image frames can be interlaced within a display of live fluoroscopic images of the patient.

公开(公告)号：US20210042927A1

公开(公告)日：2021-02-11

申请号：US16985623

申请日：2020-08-05

Applicant: LightLab Imaging, Inc.

Inventor： Gregory Patrick Amis ,  Ajay Gopinath ,  Mark Hoeveler

IPC: G06T7/00 ,  G06T11/00 ,  G06T7/38 ,  G16H50/30 ,  G16H30/40 ,  G16H50/50 ,  A61B5/02 ,  A61B5/00

Abstract: The present disclosure provides systems and methods to receiving OCT or IVUS image data frames to output one or more representations of a blood vessel segment. The image data frames may be stretched and/or aligned using various windows or bins or alignment features. Arterial features, such as the calcium burden, may be detected in each of the image data frames. The arterial features may be scored. The score may be a stent under-expansion risk. The representation may include an indication of the arterial features and their respective score. The indication may be a color coded indication.

公开(公告)号：US10902599B2

公开(公告)日：2021-01-26

申请号：US16166520

申请日：2018-10-22

Applicant: LightLab Imaging, Inc.

Inventor： Sonal Ambwani ,  Christopher E. Griffin ,  James G. Peterson ,  Satish Kaveti ,  Joel M. Friedman

IPC: G06T7/11 ,  A61B34/20 ,  G06T7/174 ,  G06T7/00 ,  G06K9/46

Abstract: The disclosure relates, in part, to computer-based visualization of stent position within a blood vessel. A stent can be visualized using intravascular data and subsequently displayed as stent struts or portions of a stent as a part of a one or more graphic user interface(s) (GUI). In one embodiment, the method includes steps to distinguish stented region(s) from background noise using an amalgamation of angular stent strut information for a given neighborhood of frames. The GUI can include views of a blood vessel generated using distance measurements and demarcating the actual stented region(s), which provides visualization of the stented region. The disclosure also relates to display of intravascular diagnostic information such as indicators. An indicator can be generated and displayed with images generated using an intravascular data collection system. The indicators can include one or more viewable graphical elements suitable for indicating diagnostic information such as stent information.

公开(公告)号：US20210004955A1

公开(公告)日：2021-01-07

申请号：US16928602

申请日：2020-07-14

Applicant: LightLab Imaging, Inc.

Inventor： Sonal Ambwani ,  Christopher E. Griffin

IPC: G06T7/00 ,  A61B5/00 ,  A61B5/06 ,  G06T7/70 ,  G06K9/46

Abstract: The disclosure relates to stent detection and shadow detection in the context of intravascular data sets obtained using a probe such as, for example, and optical coherence tomography probe or an intravascular ultrasound probe.

公开(公告)号：US20200294659A1

公开(公告)日：2020-09-17

申请号：US16821877

申请日：2020-03-17

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath ,  Mark Hoeveler

IPC: G16H40/63 ,  G06T7/13 ,  G06K9/78 ,  G06T7/62 ,  G06T7/00 ,  G16H30/20 ,  G16H30/40 ,  G16H40/40 ,  A61B34/10 ,  A61B34/00 ,  G06F3/0484

Abstract: In part, the disclosure relates to method of displaying a representation of an artery. The method may include storing an intravascular image dataset in a memory device of a diagnostic imaging system, the intravascular image dataset generated in response to intravascular imaging of a segment of an artery; automatically detecting lumen boundary of the segment on a per frame basis; automatically detecting EEL and displaying a stent sizing workflow. In part, the disclosure also relates to automatically detecting one or more regions of calcium relative to lumen boundary of the segment; calculating an angular or circumferential measurement of detected calcium for one or more frames; calculating a calcium thickness of detected calcium for one or more frames; and displaying the calcium thickness and the angular or circumferential measurement of detected calcium for a first frame of the one or more frames.

公开(公告)号：US10713786B2

公开(公告)日：2020-07-14

申请号：US16002554

申请日：2018-06-07

Applicant: LightLab Imaging, Inc.

Inventor： Sonal Ambwani ,  Christopher E. Griffin

IPC: G06T7/00 ,  A61B5/00 ,  A61B5/06 ,  G06T7/70 ,  G06K9/46

Abstract: The disclosure relates to stent detection and shadow detection in the context of intravascular data sets obtained using a probe such as, for example, and optical coherence tomography probe or an intravascular ultrasound probe.

公开(公告)号：US20200167923A1

公开(公告)日：2020-05-28

申请号：US16778252

申请日：2020-01-31

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath

IPC: G06T7/00 ,  G06T5/00 ,  A61B5/00 ,  A61B5/02 ,  G06T7/13 ,  G06T7/11

Abstract: In part, the disclosure relates to an automated method of branch detection with regard to a blood vessel imaged using an intravascular modality such as OCT, IVUS, or other imaging modalities. In one embodiment, a representation of A-lines and frames generated using an intravascular imaging system is used to identify candidate branches of a blood vessel. One or more operators such as filters can be applied to remove false positives associated with other detections.

公开(公告)号：US10646198B2

公开(公告)日：2020-05-12

申请号：US14974856

申请日：2015-12-18

Applicant: LIGHTLAB IMAGING, INC.

Inventor： James G. Peterson ,  Christopher E. Griffin ,  Sonal Ambwani

IPC: A61B8/12 ,  A61B5/00 ,  A61B5/06 ,  A61B5/02 ,  G06T7/73 ,  A61B90/00

Abstract: In part, the disclosure relates to computer-based methods, devices, and systems suitable for detecting a delivery catheter using intravascular data. In one embodiment, the delivery catheter is used to position the intravascular data collection probe. The probe can collect data suitable for generating one or more representations of a blood vessel with respect to which the delivery catheter can be detected.

公开(公告)号：US10529093B2

公开(公告)日：2020-01-07

申请号：US16146361

申请日：2018-09-28

Applicant: LightLab Imaging, Inc.

Inventor： Christopher E. Griffin ,  Sonal Ambwani ,  Satish Kaveti

IPC: G06T11/00 ,  A61B5/00 ,  A61B8/08 ,  A61B8/12 ,  A61M25/09 ,  A61B5/02 ,  A61B5/06 ,  G06T7/70 ,  G06T7/194 ,  G06T7/00

Abstract: In part, the disclosure relates to methods of guidewire detection in intravascular data sets such as scan lines, frames, images and combinations thereof. Methods of generating one or more indicia of a guidewire in a representation of blood vessel are also features of the disclosure. A carpet view is generated in one embodiment and regions of relatively higher contrast are detected as candidate guidewire regions. In one embodiment, the disclosure relates to selective removal of guidewire segments from a set of intravascular data and the display of a representation of a blood vessel via a user interface. Representations of a guidewire can be toggled on and off in one embodiment.