PREPARATION OF SITE-SPECIFIC POLYPEPTIDE CONJUGATES

    公开(公告)号:US20240424107A1

    公开(公告)日:2024-12-26

    申请号:US18628661

    申请日:2024-04-05

    Abstract: The present invention relates to a preparation of a polypeptide conjugate using an aptamer containing oxanine. In particular, the present invention relates to a composition for preparing a conjugate of a polypeptide, the composition comprising an aptamer containing oxanine, and a method of preparing a conjugate of a polypeptide using the same. The present invention also relates to a conjugate comprising a polypeptide and an aptamer containing oxanine, and a conjugate comprising a polypeptide and a drug.

    Method and apparatus for enhancing video quality based on machine learning

    公开(公告)号:US12175639B2

    公开(公告)日:2024-12-24

    申请号:US17497824

    申请日:2021-10-08

    Abstract: A video quality improvement method may comprise: inputting a structure feature map converted from current target frame by first convolution layer to first multi-task unit and second multi-task unit, which is connected to an output side of first multi-task unit, among the plurality of multi-task units; inputting a main input obtained by adding the structure feature map to a feature space, which is converted by second convolution layer from those obtained by concatenating, in channel dimension, a previous target frame and a correction frame of the previous frame to first multi-task unit; and inputting current target frame to Nth multi-task unit connected to an end of output side of second multi-task unit, wherein Nth multi-task unit outputs a correction frame of current target frame, and machine learning of the video quality improvement model is performed using an objective function calculated through the correction frame of current target frame.

    QUANTUM DEVICE INCLUDING MODERATE FLUORIATED GRAPHENE AND METHOD FOR FABRICATING SAME

    公开(公告)号:US20240371986A1

    公开(公告)日:2024-11-07

    申请号:US18654150

    申请日:2024-05-03

    Abstract: Embodiments of the present disclosure relate to a quantum device including moderate fluorinated graphene and a method for fabricating the same. According to an exemplary embodiment of the present disclosure, there is provided a quantum device including moderate fluorinated graphene, the quantum device including a substrate, a first insulating layer located on the substrate, a graphene layer located on the first insulating layer, and a second insulating layer located on the graphene layer and covering a third region excluding a first region and second region on both sides of the graphene layer, in which the first region and second region of the graphene layer are formed of moderate fluorinated graphene, and a metal layer is formed on the first region and the second region, and the metal layer makes contact at some locations on the moderate fluorinated graphene.

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