公开(公告)号：US20240032894A1

公开(公告)日：2024-02-01

申请号：US18376879

申请日：2023-10-05

Applicant: LightLab Imaging, Inc.

Inventor： James G. Peterson ,  Christopher E. Griffin ,  Sonal Ambwani

IPC: A61B8/12 ,  A61B5/00 ,  A61B5/06 ,  A61B5/02 ,  G06T7/73 ,  A61B90/00

CPC classification number: A61B8/12 ,  A61B5/6852 ,  A61B5/061 ,  A61B5/0035 ,  A61B5/02007 ,  G06T7/73 ,  A61B90/36 ,  A61B5/0066 ,  A61B5/0084 ,  G06T2207/10101 ,  G06T2207/30021

Abstract: In part, the disclosure relates to computer-based methods, devices, and systems suitable for detecting a delivery catheter using intravascular data. In one embodiment, the delivery catheter is used to position the intravascular data collection probe. The probe can collect data suitable for generating one or more representations of a blood vessel with respect to which the delivery catheter can be detected.

公开(公告)号：US20230414176A1

公开(公告)日：2023-12-28

申请号：US18367588

申请日：2023-09-13

Applicant: LightLab Imaging, Inc.

Inventor： Joseph M. Schmitt ,  Chenyang Xu

IPC: A61B5/00

CPC classification number: A61B5/6852 ,  A61B5/0066 ,  A61B5/7264

Abstract: A method and apparatus for determining properties of a tissue or tissues imaged by optical coherence tomography (OCT). In one embodiment the backscatter and attenuation of the OCT optical beam is measured and based on these measurements and indicium such as color is assigned for each portion of the image corresponding to the specific value of the backscatter and attenuation for that portion. The image is then displayed with the indicia and a user can then determine the tissue characteristics. In an alternative embodiment the tissue characteristics is classified automatically by a program given the combination of backscatter and attenuation values.

公开(公告)号：US11850089B2

公开(公告)日：2023-12-26

申请号：US16870149

申请日：2020-05-08

Applicant: LightLab Imaging, Inc.

Inventor： James G. Peterson ,  Christopher E. Griffin ,  Sonal Ambwani

IPC: A61B8/12 ,  A61B5/00 ,  A61B5/06 ,  A61B5/02 ,  G06T7/73 ,  A61B90/00

CPC classification number: A61B8/12 ,  A61B5/0035 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/02007 ,  A61B5/061 ,  A61B5/6852 ,  A61B90/36 ,  G06T7/73 ,  G06T2207/10101 ,  G06T2207/30021

Abstract: In part, the disclosure relates to computer-based methods, devices, and systems suitable for detecting a delivery catheter using intravascular data. In one embodiment, the delivery catheter is used to position the intravascular data collection probe. The probe can collect data suitable for generating one or more representations of a blood vessel with respect to which the delivery catheter can be detected.

公开(公告)号：US11741613B2

公开(公告)日：2023-08-29

申请号：US17561018

申请日：2021-12-23

Applicant: LightLab Imaging, Inc.

Inventor： Shimin Li ,  Ajay Gopinath ,  Kyle Savidge

IPC: G06N3/08 ,  G06T7/11 ,  G06N3/04 ,  G06F18/214 ,  G06F18/40 ,  G06F18/211

CPC classification number: G06T7/11 ,  G06F18/211 ,  G06F18/214 ,  G06F18/40 ,  G06N3/04 ,  G06N3/08 ,  G06V2201/03

Abstract: In part, the disclosure relates to methods, and systems suitable for evaluating image data from a patient on a real time or substantially real time basis using machine learning (ML) methods and systems. Systems and methods for improving diagnostic tools for end users such as cardiologists and imaging specialists using machine learning techniques applied to specific problems associated with intravascular images that have polar representations. Further, given the use of rotating probes to obtain image data for OCT, IVUS, and other imaging data, dealing with the two coordinate systems associated therewith creates challenges. The present disclosure addresses these and numerous other challenges relating to solving the problem of quickly imaging and diagnosis a patient such that stenting and other procedures may be applied during a single session in the cath lab.

公开(公告)号：US11633167B2

公开(公告)日：2023-04-25

申请号：US17225456

申请日：2021-04-08

Applicant: LightLab Imaging, Inc.

Inventor： Lorina Dascal ,  Itai Winkler

IPC: G06K9/00 ,  A61B6/00 ,  G06T7/00 ,  A61B5/00 ,  A61B8/12 ,  G06T5/50

Abstract: The disclosure relates generally to the field of vascular system and peripheral vascular system data collection, imaging, image processing and feature detection relating thereto. In part, the disclosure more specifically relates to methods for detecting position and size of contrast cloud in an x-ray image including with respect to a sequence of x-ray images during intravascular imaging. Methods of detecting and extracting metallic wires from x-ray images are also described herein such as guidewires used in coronary procedures. Further, methods for of registering vascular trees for one or more images, such as in sequences of x-ray images, are disclosed. In part, the disclosure relates to processing, tracking and registering angiography images and elements in such images. The registration can be performed relative to images from an intravascular imaging modality such as, for example, optical coherence tomography (OCT) or intravascular ultrasound (IVUS).

公开(公告)号：US20230054891A1

公开(公告)日：2023-02-23

申请号：US17890672

申请日：2022-08-18

Applicant: LightLab Imaging, Inc.

Inventor： Wei Chiu ,  Shimin Li ,  Ajay Gopinath ,  Jacob Segev ,  Lorina Dascal

IPC: A61B5/02 ,  G16H30/20

Abstract: Systems and methods are disclosed for identifying features of a blood vessel using extravascular and intravascular images in order to estimate a virtual flow reserve (VFR) of the imaged blood vessel. Aspects of the disclosure include using extravascular images to estimate the size of the blood vessel in regions that have not been intravascularly imaged. The VFR estimation may be based on a resistance model that incorporates both the intravascular image data and the estimated blood vessel size. In other aspects, multiangled extravascular images are captured and analyzed in order to identify the size and orientation of branch vessels.

公开(公告)号：US20230018499A1

公开(公告)日：2023-01-19

申请号：US17862991

申请日：2022-07-12

Applicant: LightLab Imaging, Inc.

Inventor： Justin Akira Blaber ,  Ajay Gopinath ,  Humphrey Chen ,  Kyle Edward Savidge ,  Angela Zhang ,  Gregory Patrick Amis

IPC: G06T7/00 ,  G16H50/20 ,  G16H30/40

Abstract: Aspects of the disclosure relate to systems, methods, and algorithms to train a machine learning model or neural network to classify OCT images. The neural network or machine learning model can receive annotated OCT images indicating which portions of the OCT image are blocked and which are clear as well as a classification of the OCT image as clear or blocked. After training, the neural network can be used to classify one or more new OCT images. A user interface can be provided to output the results of the classification and summarize the analysis of the one or more OCT images.

公开(公告)号：US11435233B2

公开(公告)日：2022-09-06

申请号：US16743603

申请日：2020-01-15

Applicant: LightLab Imaging, Inc.

Inventor： Joel M. Friedman ,  Amr Elbasiony

IPC: G01J9/02 ,  G06T7/00 ,  A61B8/12 ,  G06T7/12 ,  A61B5/00

Abstract: In part, the invention relates to systems and methods of calibrating a plurality of frames generated with respect to a blood vessel as a result of a pullback of an intravascular imaging probe being pullback through the vessel. A calibration feature disposed in the frames that changes between a subset of the frames can be used to perform calibration. Calibration can be performed post-pullback. Various filters and image processing techniques can be used to identify one or more feature in the frames including, without limitation, a calibration feature, a guidewire, a side branch, a stent strut, a lumen of the blood vessel, and other features. The feature can be displayed using a graphic user interface.

公开(公告)号：US11311200B1

公开(公告)日：2022-04-26

申请号：US16186040

申请日：2018-11-09

Applicant: LightLab Imaging, Inc.

Inventor： Ajay Gopinath ,  Samir Farah ,  Johan Svanerudh

IPC: A61B5/0215 ,  A61B5/02 ,  A61B5/00 ,  A61B5/026

Abstract: In part, the disclosure relates to computer-based methods, and systems suitable for evaluating a subject to determine the appropriate diagnostic tools for assessing coronary arteries. This can include assessing various blood pressure values during a resting state (without inducing hyperemia). These systems and methods can assess a patient and identify coronary dominance on per patient basis. In turn, this assessment can be used to recommend whether a resting index is appropriate or if another index such as FFR or others such be obtained diagnostic metric such as a pressure value-based ratio.

公开(公告)号：US11241154B2

公开(公告)日：2022-02-08

申请号：US15466246

申请日：2017-03-22

Applicant: LightLab Imaging, Inc.

Inventor： Desmond Adler ,  Joseph M. Schmitt ,  Mattias Dahlberg ,  Par Gustafsson ,  Ulrik Hubinette ,  Magnus Samuelsson ,  Johan Svanerudh

IPC: A61B5/05 ,  A61B5/00 ,  A61B5/0215 ,  A61B6/00 ,  A61B8/08 ,  A61B8/12 ,  A61B8/00

Abstract: In part, the invention relates to an image data collection system. The system can include an interferometer having a reference arm that includes a first optical fiber of length of L1 and a sample arm that includes a second optical fiber of length of L2 and a first rotary coupler configured to interface with an optical tomography imaging probe, wherein the rotary coupler is in optical communication with the sample arm. In one embodiment, L2 is greater than about 5 meters. The first optical fiber and the second optical fiber can both be disposed in a common protective sheath. In one embodiment, the system further includes an optical element configured to adjust the optical path length of the reference arm, wherein the optical element is in optical communication with the reference arm and wherein the optical element is transmissive or reflective.