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公开(公告)号:US20030152999A1
公开(公告)日:2003-08-14
申请号:US09904766
申请日:2001-07-12
Applicant: Genentech, Inc.
Inventor: Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: G01N033/53 , C07H021/04 , C12N009/00 , A61K038/17 , C12P021/02 , C12N005/06 , C07K014/435
CPC classification number: C07K14/47 , G01N33/68 , G01N2333/485
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030152922A1
公开(公告)日:2003-08-14
申请号:US09904532
申请日:2001-07-13
Applicant: Genentech, Inc.
Inventor: Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: C12Q001/68 , G01N033/53 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , A61K038/17 , C07K014/435
CPC classification number: C07K14/47 , G01N33/68 , G01N2333/485
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030148419A1
公开(公告)日:2003-08-07
申请号:US09903603
申请日:2001-07-11
Applicant: Genentech, Inc.
Inventor: Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: G01N033/53 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06
CPC classification number: C07K14/47 , G01N33/68 , G01N2333/485
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030130182A1
公开(公告)日:2003-07-10
申请号:US09989862
申请日:2001-11-19
Applicant: Genentech, Inc.
Inventor: Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Ivar J. Kljavin , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
IPC: A61K038/17 , C12P021/02 , C12N005/06 , G01N033/53 , C07H021/04 , C07K014/435 , C07K016/40
CPC classification number: G01N33/567 , A01K67/0275 , A01K2217/05 , A01K2227/105 , A01K2267/03 , C07K14/47 , C12N15/8509 , G01N33/57484 , G01N2800/52
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030124531A1
公开(公告)日:2003-07-03
申请号:US09997614
申请日:2001-11-15
Applicant: Genentech, Inc.
Inventor: Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Ivar J. Kljavin , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
IPC: C12Q001/68 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K014/435
CPC classification number: C07K14/47 , A61K38/00 , A61K39/00 , C07K14/52 , C07K14/705 , C07K16/18 , C07K2319/00 , C12N9/00 , G01N33/5008 , G01N33/5011 , G01N33/502 , G01N33/57484 , G01N33/68 , G01N33/6842 , Y10S530/866
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030119055A1
公开(公告)日:2003-06-26
申请号:US09997585
申请日:2001-11-15
Applicant: Genentech, Inc.
Inventor: Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Ivar J. Kljavin , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
IPC: G01N033/53 , C07H021/04 , C12N009/00 , C12P021/02 , C12N005/06 , C07K014/435 , C07K016/40
CPC classification number: C07K14/47 , A61K38/00 , A61K39/00 , C07K14/52 , C07K14/705 , C07K16/18 , C07K2319/00 , C12N9/00 , G01N33/5008 , G01N33/5011 , G01N33/502 , G01N33/57484 , G01N33/68 , G01N33/6842 , Y10S530/866
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030113718A1
公开(公告)日:2003-06-19
申请号:US09902979
申请日:2001-07-10
Applicant: Genentech, Inc.
Inventor: Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: C12Q001/68 , G01N033/53 , C07H021/04 , C12N009/00 , C07K014/435 , A61K038/17 , C12P021/02 , C12N005/06
CPC classification number: A61K38/17 , C07H21/04 , C07K14/435 , C12N5/06 , C12N9/00 , C12P21/02 , C12Q1/68 , G01N33/53
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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108.
公开(公告)号:US20030105013A1
公开(公告)日:2003-06-05
申请号:US10223090
申请日:2002-08-16
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Napoleone Ferrara , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Kenneth J. Hillan , Scot A. Marsters , James Pan , Jean-Philippe F. Stephan , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Weilan Ye
IPC: A61K038/17 , C12P021/02 , C12N005/06 , C07K014/435 , C07H021/04 , C12N009/00
CPC classification number: A61K38/17 , C07H21/04 , C07K14/435 , C07K14/47 , C12N5/06 , C12N9/00 , C12P21/02
Abstract: Compositions and methods are disclosed for stimulating or inhibiting angiogenesis and/or cardiovascularization in mammals, including humans. Pharmaceutical compositions are based on polypeptides or antagonists thereto that have been identified for one or more of these uses. Disorders that can be diagnosed, prevented, or treated by the compositions herein include trauma such as wounds, various cancers, and disorders of the vessels including atherosclerosis and cardiac hypertrophy. In addition, the present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030104469A1
公开(公告)日:2003-06-05
申请号:US09907652
申请日:2001-07-17
Applicant: Genentech, Inc.
Inventor: Avi Ashkenazi , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Jennie P. Mather , James Pan , Niclolas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: G01N033/53 , C12N009/00 , C07H021/04 , C12P021/02 , C12N005/06 , C07K014/435 , C07K016/40
CPC classification number: C07K14/47 , G01N33/68 , G01N2333/485
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030096744A1
公开(公告)日:2003-05-22
申请号:US09978187
申请日:2002-01-28
Applicant: Genentech, Inc.
Inventor: Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Ellen Filvaroff , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Kenneth J. Hillan , Ivar J. Kljavin , Sophia S. Kuo , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , David L. Shelton , Timothy A. Stewart , Daniel Tumas , P. Mickey Williams , William I. Wood
IPC: A61K038/17 , C12P021/02 , C12N005/06 , C07K014/435 , C07H021/04 , C12N009/00
CPC classification number: C07K14/47 , A61K38/00 , A61K48/00 , C07K14/4702 , C07K14/4703 , C07K14/475 , C07K14/52 , C07K14/521 , C07K14/54 , C07K14/705 , C07K14/70503 , C07K14/70578 , C07K16/18 , C07K16/28 , C07K2317/24 , C07K2319/00 , C07K2319/30 , C12N9/00 , C12N2799/026 , C12N2799/027 , G01N33/573 , G01N33/57484 , G01N33/68 , G01N2333/99 , G01N2800/042
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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