公开(公告)号：US20200002565A1

公开(公告)日：2020-01-02

申请号：US16490752

申请日：2018-03-05

Applicant: HARLAND MEDICAL SYSTEMS, INC.

Inventor： Paul BUSCEMI ,  Gregory CARLSON

IPC: C09D139/06 ,  C09D5/14 ,  A61L29/08 ,  A61L29/14

Abstract: The present invention relates to coatings for devices such as medical devices that are useful for coating a variety of different types of material surfaces, including polymer and metal surfaces. The present invention also includes the method of using the coated device and methods to make the coated device and coating.

公开(公告)号：US10517999B2

公开(公告)日：2019-12-31

申请号：US15485390

申请日：2017-04-12

Applicant: Cardiac Pacemakers, Inc.

Inventor： John Kummailil ,  Paul V. Grosso ,  Joseph T. Delaney, Jr.

IPC: A61L29/06 ,  A61L29/08 ,  A61L29/14 ,  A61L31/10 ,  A61L31/14 ,  B05D1/00 ,  B05D1/02 ,  B05D1/18 ,  C08J7/04 ,  C09D139/06

Abstract: A medical device for insertion or implantation in a body includes a polymer substrate and a layer of poly(vinyl pyrrolidone-alt-maleic anhydride) formed on a surface of the polymer substrate. Polymer chains of the poly(vinyl pyrrolidone-alt-maleic anhydride) are entangled with the polymer substrate.

公开(公告)号：US20190388593A1

公开(公告)日：2019-12-26

申请号：US16561535

申请日：2019-09-05

Applicant: TERUMO KABUSHIKI KAISHA

Inventor： Manabu MIURA ,  Yasunobu ZUSHI ,  Shinya KUSUNOKI

IPC: A61L29/06 ,  A61M25/00 ,  A61L29/14

Abstract: Provided is an indwelling catheter which is stiff when being inserted into a vessel such as a blood vessel, softens after indwelling in the vessel, and conforms to a shape in a direction in which the vessel runs. In the indwelling catheter, the maximum value of a catheter repulsive force in a dry state at 25° C. is 0.10 N or more; the maximum value of the catheter repulsive force when immersed in warm water at 37° C. is 0.01 to 0.25 N; a ratio of the maximum value of the catheter repulsive force in a dry state at 25° C. to the maximum value of the catheter repulsive force when immersed in warm water at 37° C. is in a range of 3.5:1 or more; and the maximum value of the catheter repulsive force when immersed in warm water at 37° C. is 0.027 N or less after 5 minutes from indwelling.

公开(公告)号：US10513597B2

公开(公告)日：2019-12-24

申请号：US15642758

申请日：2017-07-06

Applicant: Medtronic Vascular, Inc.

Inventor： Mingfei Chen

IPC: C08K5/20 ,  A61L29/06 ,  A61L29/14 ,  A61L31/06 ,  A61L31/14 ,  C08J5/18 ,  C08K5/00

Abstract: A plasticized nylon and a medical device including plasticized nylon. The medical device may be a dilatation balloon. Also disclosed are methods of plasticizing nylon.

公开(公告)号：US10507269B2

公开(公告)日：2019-12-17

申请号：US16373850

申请日：2019-04-03

Applicant: Medline Industries, Inc.

Inventor： Lecon Woo ,  William Anderson

IPC: A61L33/04 ,  A61L29/14 ,  A61L29/16 ,  A61L33/00

Abstract: A liquid excipient is added to a lock solution formulation containing a lower alcohol and an anti-coagulant, antibiotic, and/or anti-microbial, such as the ethanol and tri-sodium citrate lock solution formulation, to prevent citrate from crystallizing in catheters made from silicone. The locking solution could include a liquid excipient, such as glycerol, polysorbate-20, or polyethylene glycol (PEG)-400, along with a lower alcohol, such as ethanol, and an anti-coagulant, such as tri-sodium citrate, antibiotic, and/or anti-microbial.

公开(公告)号：US20190352848A1

公开(公告)日：2019-11-21

申请号：US16411709

申请日：2019-05-14

Applicant: Hitachi Metals, Ltd.

Inventor： Seiichi KASHIMURA ,  Masamichi KISHI ,  Takanobu WATANABE ,  Kimika KUDO ,  Masashi ARAI

IPC: D07B5/00 ,  D07B1/16 ,  A61L29/08 ,  A61L29/04 ,  A61L29/14 ,  A61L29/12

Abstract: A cable includes a sheath, and a coating film covering a circumference of the sheath. The coating film adheres to the sheath. The static friction coefficient of a surface of the coating film is smaller than the static friction coefficient of a surface of the sheath. The adhesion strength between the sheath and the coating film is 0.30 MPa or more.

公开(公告)号：US20190351081A1

公开(公告)日：2019-11-21

申请号：US16475200

申请日：2018-02-12

Applicant: HOYA CORPORATION

Inventor： Harald HUBER

IPC: A61L2/08 ,  A61L2/10 ,  A61L2/232 ,  A61L29/10 ,  A61L29/12 ,  A61L29/14

Abstract: The invention refers to an endoscope including at least one channel which may be contaminated in use, wherein the channel wall of the at least one channel is formed of a material having properties capable of photocatalysis. The invention further refers to a method for cleaning such an endoscope including the steps of: connecting the endoscope to a reprocessing device, performing a photocatalytic treatment at least in the at least one channel for the purpose of the decomposition of organic residues on the surface of the channel, and rinsing the endoscope. The invention further refers to a cleaning device for cleaning such an endoscope.

公开(公告)号：US20190328932A1

公开(公告)日：2019-10-31

申请号：US16506454

申请日：2019-07-09

Applicant: FUJIFILM Corporation

Inventor： Toshihide YOSHITANI ,  Nobuharu TAKAHASHI

IPC: A61L27/34 ,  A61L29/08 ,  A61L29/14

Abstract: Provided are a medical lubricating member including a silicone base material, and a lubricating coated film which is laminated on at least one surface of the silicone base material, in which the silicone base material contains a reactive functional group in the surface on which the lubricating coated film is laminated, and the lubricating coated film is a film formed of a composition containing a hydrophilic polymer and polyisocyanate; a medical device using the medical lubricating member; and a method of producing the medical lubricating member.

公开(公告)号：US10441947B2

公开(公告)日：2019-10-15

申请号：US15232085

申请日：2016-08-09

Applicant: Ethicon, Inc.

Inventor： Duan Li Ou

IPC: A61L29/14 ,  B01J31/22 ,  A61L29/08 ,  A61L31/10 ,  C09D183/04 ,  A61L31/14 ,  C10M107/50 ,  C10M139/06 ,  B01J31/16 ,  C08G77/12 ,  C08G77/20 ,  C08L83/00 ,  B05D5/08

Abstract: Novel, lubricious coatings for medical devices are disclosed. The coatings provide improved lubricity and durability, and are readily applied in coating processes. The present invention is also directed to a novel platinum catalyst for use in such coatings. The catalyst provides for rapid curing, while inhibiting cross-linking at ambient temperatures, thereby improving the production pot life of the coatings.

公开(公告)号：US10441531B2

公开(公告)日：2019-10-15

申请号：US14442387

申请日：2013-11-12

Applicant: Bloodworks

Inventor： Dominic Chung ,  Jose Aron Lopez ,  Minhua Ling ,  Junmei Chen ,  Xiaoyun Fu

IPC: A61K38/00 ,  A61K9/00 ,  C07K14/755 ,  A61L29/08 ,  A61L29/04 ,  A61L31/14 ,  A61L31/16 ,  A61L31/10 ,  C07K14/775 ,  A61L29/14 ,  A61L29/16 ,  A61K47/42

Abstract: Compositions and methods are described for preventing or reducing protein loss due to protein aggregation, denaturation, and adsorption to surfaces. Also described are compositions and methods for preventing or reducing the fouling or clogging of medical devices that come into contact with blood, such as catheters. Also described are methods to treat diseases caused by activation of the microvasculature.