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    Intravascular Optical Coherence Tomography System with Pressure Monitoring Interface and Accessories
    91.
    发明申请
    Intravascular Optical Coherence Tomography System with Pressure Monitoring Interface and Accessories 审中-公开
    血管内光学相干断层扫描系统与压力监测接口和附件

    公开(公告)号：US20140187929A1

    公开(公告)日：2014-07-03

    申请号：US14151340

    申请日：2014-01-09

    Applicant: Joseph M. Schmitt ,  Christopher Petroff

    Inventor： Joseph M. Schmitt ,  Christopher Petroff

    IPC: A61B5/0215 ,  A61B5/00

    CPC classification number: A61B5/02154 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/02007 ,  A61B5/0215 ,  A61B5/6852 ,  A61B5/742

    Abstract: An optical coherence tomography system and method with integrated pressure measurement. In one embodiment the system includes an interferometer including: a wavelength swept laser; a source arm in communication with the wavelength swept laser; a reference arm in communication with a reference reflector; a first photodetector having a signal output; a detector arm in communication with the first photodetector, a probe interface; a sample arm in communication with a first optical connector of the probe interface; an acquisition and display system comprising: an A/D converter having a signal input in communication with the first photodetector signal output and a signal output; a processor system in communication with the A/D converter signal output; and a display in communication with the processor system; and a probe comprising a pressure sensor and configured for connection to the first optical connector of the probe interface, wherein the pressure transducer comprises an optical pressure transducer.

    Abstract translation: 光学相干断层扫描系统和集成压力测量方法。 在一个实施例中，系统包括干涉仪，包括：波长扫描激光; 与波长扫描激光器通信的源臂; 与参考反射器连通的参考臂; 具有信号输出的第一光电检测器; 与第一光电检测器连通的检测器臂，探针接口; 与所述探针接口的第一光学连接器连通的样品臂; 一种采集和显示系统，包括：具有与第一光电检测器信号输出通信的信号输入的信号输出的A / D转换器; 与A / D转换器信号输出通信的处理器系统; 以及与处理器系统通信的显示器; 以及探针，其包括压力传感器并且被配置为连接到所述探针接口的所述第一光学连接器，其中所述压力传感器包括光学压力传感器。

    Optical coherence tomography control systems and methods
    92.
    发明授权
    Optical coherence tomography control systems and methods 有权
    光学相干断层扫描控制系统和方法

    公开(公告)号：US08687201B2

    公开(公告)日：2014-04-01

    申请号：US13789839

    申请日：2013-03-08

    Applicant: Desmond Adler

    Inventor： Desmond Adler

    IPC: G01B11/02

    CPC classification number: G01B9/02091 ,  A61B5/0066 ,  A61B5/0084 ,  G01B9/02004 ,  G01B9/02067 ,  H01S3/0092 ,  H01S3/1062 ,  H01S3/1396 ,  H01S5/183

    Abstract: In part, the invention relates to methods, devices, and systems suitable for controlling a light source. The light source is configured for use in a data collection system such as an optical coherence tomography system. The light source can be controlled with a drive waveform. Linearizing and symmetrizing parameters of the light source such as forward and backward scan durations is achieved using a suitable drive waveform. Phase, amplitude, and other parameters for different harmonics of a fundamental wave can be identified that improve operating parameters such as the duty cycle and peak frequency matching between scans. The fundamental wave and one or more of such harmonics can be combined to generate the suitable drive wave form. The light source can include a tunable light source that includes or is in optical communication with a tunable filter.

    Abstract translation: 部分地，本发明涉及适于控制光源的方法，装置和系统。 光源被配置用于诸如光学相干断层摄影系统的数据采集系统中。 光源可以用驱动波形控制。 使用合适的驱动波形实现光源的线性化和对称性参数，如前进和后退扫描持续时间。 可以确定基波不同谐波的相位，幅度和其他参数，以提高扫描之间的占空比和峰值频率匹配等工作参数。 基波和这些谐波中的一个或多个可以组合以产生合适的驱动波形。 光源可以包括可调谐光源，其包括或者与可调谐滤光器光学通信。

    Lumen Morphology and Vascular Resistance Measurements Data Collection Systems, Apparatus and Methods
    93.
    发明申请
    Lumen Morphology and Vascular Resistance Measurements Data Collection Systems, Apparatus and Methods 有权
    流明形态和血管阻力测量数据收集系统，装置和方法

    公开(公告)号：US20130072805A1

    公开(公告)日：2013-03-21

    申请号：US13617441

    申请日：2012-09-14

    Applicant: Joseph M. Schmitt ,  Joel M. Friedman ,  Christopher Petroff ,  Amr Elbasiony

    Inventor： Joseph M. Schmitt ,  Joel M. Friedman ,  Christopher Petroff ,  Amr Elbasiony

    IPC: A61B5/00

    CPC classification number: A61B5/0066 ,  A61B5/02007 ,  A61B5/6852 ,  A61B2034/102 ,  A61F2/82 ,  G06T7/0012 ,  G06T2200/24 ,  G06T2207/10016 ,  G06T2207/10101 ,  G06T2207/30101

    Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

    Abstract translation: 一种自动定位在血管图像中的管腔边界在容器中的位置以及从测量血管直径的方法和装置。 从容器的直径和估计的血流速度，然后确定许多临床显着的生理参数，并且生成各种用户显示关注。 这些图像和参数的一个用途是帮助临床医生放置支架。 在一个实施例中，该系统使用这些测量来允许临床医生模拟支架的放置并确定放置的影响。 此外，从这些患者参数，然后执行各种患者治疗。

    Intensity Noise Reduction Methods and Apparatus for Interferometric Sensing and Imaging Systems
    96.
    发明申请
    Intensity Noise Reduction Methods and Apparatus for Interferometric Sensing and Imaging Systems 有权
    用于干涉测量和成像系统的强度降噪方法和装置

    公开(公告)号：US20110228280A1

    公开(公告)日：2011-09-22

    申请号：US13050410

    申请日：2011-03-17

    Applicant: Joseph M. Schmitt ,  Victor Grinberg

    Inventor： Joseph M. Schmitt ,  Victor Grinberg

    IPC: G01B9/02

    CPC classification number: G01B9/02055 ,  G01B9/02004 ,  G01B9/02044 ,  G01B9/02074 ,  G01B9/02083 ,  H03G3/3084 ,  H04B10/616 ,  H04B10/671

    Abstract: In part, aspects of the invention relate to methods, apparatus, and systems for intensity and/or pattern line noise reduction in a data collection system such as an optical coherence tomography system that uses an electromagnetic radiation source and interferometric principles. In one embodiment, the noise is intensity noise or line pattern noise and the source is a laser such as a swept laser. One or more attenuators responsive to one or more control signals can be used in conjunction with an analog or digital feedback network in one embodiment.

    Abstract translation: 部分地，本发明的方面涉及数据采集系统中的强度和/或图案线噪声降低的方法，装置和系统，例如使用电磁辐射源和干涉原理的光学相干断层摄影系统。 在一个实施例中，噪声是强度噪声或线图案噪声，并且源是诸如扫描激光器的激光器。 在一个实施例中，响应于一个或多个控制信号的一个或多个衰减器可以与模拟或数字反馈网络结合使用。

    Intravascular Measurement And Data Collections Systems
    98.
    发明申请
    Intravascular Measurement And Data Collections Systems 有权

    公开(公告)号：US20250082273A1

    公开(公告)日：2025-03-13

    申请号：US18954972

    申请日：2024-11-21

    Applicant: LightLab Imaging, Inc.

    Inventor： Joseph M. Schmitt ,  Chenyang Xu

    IPC: A61B5/00

    Abstract: A method and apparatus for determining properties of a tissue or tissues imaged by optical coherence tomography (OCT). In one embodiment the backscatter and attenuation of the OCT optical beam is measured and based on these measurements and indicium such as color is assigned for each portion of the image corresponding to the specific value of the backscatter and attenuation for that portion. The image is then displayed with the indicia and a user can then determine the tissue characteristics. In an alternative embodiment the tissue characteristics is classified automatically by a program given the combination of backscatter and attenuation values.

    Lumen morphology and vascular resistance measurements data collection systems apparatus and methods
    99.
    发明授权
    Lumen morphology and vascular resistance measurements data collection systems apparatus and methods 有权

    公开(公告)号：US12150738B2

    公开(公告)日：2024-11-26

    申请号：US18524893

    申请日：2023-11-30

    Applicant: LightLab Imaging, Inc.

    Inventor： Joseph M. Schmitt ,  Joel M. Friedman ,  Christopher Petroff ,  Amr Elbasiony

    IPC: A61B5/02 ,  A61B5/00

    Abstract: A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

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