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公开(公告)号：US20200268003A1
公开(公告)日：2020-08-27
申请号：US16794462
申请日：2020-02-19
Inventor： Ranjith Ramanathan , Gretchen G. Mafi , Deborah L. VanOverbeke
Abstract: According one embodiment, a post-harvest processing technology has been developed that enhances the red color of dark cutting beef to a near-normal or normal red color through the use, in one embodiment, of a Rosemary solution in a concentration of between 0.1% and 0.2% Rosemary which is applied to the beef, after which it is stored in a nitrite-embedded film packaging for a predetermined period of time. Various embodiments indicate that that nitrite-embedded packaging and, more particularly, nitrite-embedded packaging in combination with the use of pre-storage antioxidant wash, has the potential to improve surface color of dark-cutting beef.
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公开(公告)号：US10676423B2
公开(公告)日：2020-06-09
申请号：US16483636
申请日：2018-02-20
Inventor： Jimmie Dean Weaver , Kip Allen Teegardin , Amandeep Arora
IPC: C07C227/18 , C07C319/12 , C07D209/20 , C07D207/16 , C07D233/64 , C07C277/08
Abstract: Methods of synthesizing polyfluorinated amino acid derivatives are disclosed, along with polyfluorinated amino acid derivatives produced from said methods, as well as compositions containing same. The synthesis methods utilize an oxazolone and a perfluoroarene to produce the polyfluorinated amino acid derivatives.
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公开(公告)号：US20190262488A1
公开(公告)日：2019-08-29
申请号：US16409069
申请日：2019-05-10
Inventor： RAVIRAJSINH JADEJA , YEN-CON HUNG
Abstract: According to an embodiment, there is provided herein a method of using electrolyzed oxidizing water ice (EO ice) as a Cleaning-In-Place (CIP) method that reduces antimicrobial contamination. One embodiment is utilized in connection with beef grinders. In one embodiment, EO ice was prepared by freezing 200 mg/L free chlorine-containing EO water at 20° C. overnight. The EO ice and, optionally, EO ice/water mixture was then ground within an operating meat grinder. The EO ice treatment in combination with EO water has the potential to reduce cross-contamination and could serve as an easy to apply antimicrobial intervention to improve overall safety of ground beef.
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公开(公告)号：US20190256488A1
公开(公告)日：2019-08-22
申请号：US16404110
申请日：2019-05-06
Inventor： Jimmie Dean Weaver , Sameera SENAWEERA
IPC: C07D319/08 , C07D413/10 , C07D405/04 , C07D405/10
Abstract: This disclosure relates generally to the facile and selective mono-perfluoro and poly-fluoroarylation of Meldrum's acid to generate a versatile synthon for highly fluorinated alpha-phenyl acetic acid derivatives which provide straightforward access to fluorinated building blocks. The reaction takes place quickly and all products were isolated without the need for chromatography. An embodiment provides an alternative strategy to access alpha-arylated Meldrum's acids which avoids the need for aryl-Pb(IV) salts or diaryliodonium salts and provides access to the tertiary product which was not previously synthetically accessible. The synthetic versatility and utility of the Meldrum's acid products is demonstrated by subjecting the products to several derivatizations of the Meldrum's acid products as well as photocatalytic hydrodefluorination which provide access to difficult but valuable synthetic targets such as multifluorinated aromatics.
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公开(公告)号：US20190184601A1
公开(公告)日：2019-06-20
申请号：US16310570
申请日：2017-06-20
Inventor： Matthew Tyler LEY , Kristopher Jacob LEFLORE
CPC classification number: B28B23/0031 , B28B7/0094 , G01N33/383
Abstract: This system includes a concrete identification technology that is used in taking, testing, monitoring, and labeling concrete samples or members using custom labels called a tag. This tag comprises a series of corresponding labels, one for the outside of the form, and on for the inside of the form that becomes part of the concrete sample. These tags are physically bonded to the concrete specimen with only minimal impact on its shape and properties. In some embodiments the tags will contain a hook-and-loop or fiber type surface texture (protrusions) which is placed in the form with the protrusions facing the fresh concrete. The tag can also contain electronic circuitry to gather and track information about the concrete and the surrounding environment. This will eliminate the need to relabel the samples after demolding while also measuring a number of other parameters about the concrete and its performance.
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Patent Agency Ranking
公开(公告)号：US20190054057A1
公开(公告)日：2019-02-21
申请号：US16079730
申请日：2017-03-08
Applicant: THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY OFFICE OF INTELLECTUAL PROPERTY MANAGEMENT
Inventor： Guolong Zhang
IPC: A61K31/225 , A61K31/222 , A61K31/216 , A61K31/7076 , A23K20/158 , A23K20/153 , A23K20/111 , A23K50/75
Abstract: Provided herein are small-molecule compounds and combinations thereof that enhance the synthesis of animal endogenous genus host defense peptides, which display potent antimicrobial and immunomodulatory activities. They thus represent alternatives to antibiotics for disease control and prevention for use in animals and humans. Examples of the small molecule compounds include histone deacetylase inhibitors, mono- and disaccharide sugars, cyclic adenosine monophosphate (cAMP) signaling agonists, and cyclooxygenase -2 (COX-2) inhibitors. Synergistic combinations include short-chain fatty acids, their chemical analogs or histone deacetylase inhibitors with other fatty acids, sugars, cAMP signaling agonists, and/or COX-2 inhibitors.
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97.发明申请公开(公告)号：US20190041419A1
公开(公告)日：2019-02-07
申请号：US16057239
申请日：2018-08-07
Inventor： HISHAM FADLALLAH M. ABUELLA , SABIT EKIN , MURAT UYSAL
IPC: G01P3/36
CPC classification number: G01P3/36
Abstract: There is provided herein a visible light-based speed estimation method ViLDAR. By using the received light intensity of a vehicle's LED headlight, the vehicle speed can be accurately estimated for a wide range of incidence angle. Linear LS method is used in one embodiment of a speed estimation algorithm. The impact of system parameters on speed estimation error and the performance of algorithm for different speed and estimation duration are provided. Some embodiments operate best at a certain distances where the received light intensity (power) reading can provide estimation results with high accuracy, which distances are termed a reliable region of operation. In addition to speed estimation, potential applications of ViLDAR idea are ranging detection and collision avoidance for autonomous vehicles.
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98.发明申请公开(公告)号：US20180320146A1
公开(公告)日：2018-11-08
申请号：US16030259
申请日：2018-07-09
Inventor： Antonius G.P. Oomens
IPC: C12N7/00 , C07K14/005 , C12Q1/06
CPC classification number: C12N7/00 , A61K2039/5254 , A61K2039/5258 , C07K14/005 , C12N2760/18511 , C12N2760/18522 , C12N2760/18523 , C12N2760/18534 , C12N2760/18562 , C12Q1/06 , G01N2333/115 , G01N2500/00
Abstract: Highly antigenic yet safe vaccines against diseases caused by Paramyxoviridae viruses such as respiratory syncytial virus (RSV) are provided. The vaccines comprise attenuated Paramyxoviridae viruses with high antigenicity but which display impaired cell-to-cell transmission as a result of genetic manipulation of the gene encoding the matrix (M) protein. In the viruses, the M protein is absent or mutated to a less active form. Screening or assay systems and methods for evaluating the infectivity of mutant M proteins anf for identifying suitable M candidates for live-attenuated vaccine virus and VLP production, are also provided.
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99.发明申请公开(公告)号：US20180266957A1
公开(公告)日：2018-09-20
申请号：US15542519
申请日：2016-01-15
Inventor： Eduardo Gardenali Yukihara
CPC classification number: G01N21/6456 , A61B1/043 , G01N21/6428 , G02B21/002 , G06K9/40
Abstract: There is provided a method for correcting “pixel bleeding” caused by slow luminescence centers in laser scanning imaging (e.g., X-ray imaging using photostimulable phosphors and 2D dosimetry using optically stimulated luminescence). An embodiment uses a deconvolution procedure that takes into account the lifetime of the slow luminescence center and can be further constrained by the detection of fast and slow luminescence centers and combining line scans in opposite directions. An approach has been tested using simulated data and demonstrated experimentally by applying it to image reconstruction of two types of Al2O3 X-ray detector films (Al2O3:C and Al2O3:C,Mg), whose use in 2D dosimetry in conjunction with laser-scanning readout has so far been prevented by slow luminescence centers (35 ms lifetime from F-centers). We show that the algorithm allows the imaging using Al2O3 detectors 300 times faster than generally allowed considering the lifetime of the main luminescence centers.
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公开(公告)号：US10064862B2
公开(公告)日：2018-09-04
申请号：US15123030
申请日：2015-03-03
IPC: A61K31/522 , A61K31/517 , A61K31/4709 , A61K31/352 , A61K31/4196 , A61K31/422 , A61K31/4375 , A61K31/473 , A61K31/4743 , A61K31/4365 , A61K9/00
Abstract: Methods and compositions for preventing and/or treating viral infections are provided. The methods involve administering an agent that stabilizes or enhances Axin1 activity, e.g. and agent that inhibits tankyrase. Administration of the agent stimulates or increases interferon activity, thereby preventing or lessening at least one symptom of virus infection. The virus infection may be caused by a respiratory virus such as influenza vims.
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