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1.
公开(公告)号:US09328340B2
公开(公告)日:2016-05-03
申请号:US13762151
申请日:2013-02-07
Applicant: aTyr Pharma, Inc.
Inventor: Jeffry Dean Watkins , Alain Philippe Vasserot , Leslie Ann Greene , Ryan Andrew Adams , Kyle P. Chiang , Wei Zhang , Kristi Helen Piehl , Fei Hong , Alina He
IPC: A61K38/53 , C12N9/00 , A61K39/395 , A61K45/06
CPC classification number: A61K38/53 , A61K39/39541 , A61K45/06 , C12N9/93 , C12Y601/01021
Abstract: Inflammatory and other cellular response-modulating compositions are provided comprising aminoacyl-tRNA synthetase polypeptides, including active fragments and/or variants thereof. Also provided are methods of using such compositions in the treatment of conditions that benefit from the modulation of inflammation, such as inflammatory diseases or conditions.
Abstract translation: 提供包含氨基-tRNA合成酶多肽的炎症和其它细胞应答调节组合物,包括其活性片段和/或变体。 还提供了使用这些组合物来治疗受益于炎症疾病或病症等炎症调节的病症的方法。
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2.
公开(公告)号:US09540628B2
公开(公告)日:2017-01-10
申请号:US14541792
申请日:2014-11-14
Applicant: aTyr Pharma, Inc.
Inventor: Jeffry Dean Watkins , Alain Philippe Vasserot , Leslie Ann Greene , Ryan Andrew Adams , Kyle P. Chiang , Wei Zhang , Kristi Helen Piehl , Fei Hong , Alina He
IPC: C07H21/04 , C12N9/00 , A61K38/53 , A61K39/395 , A61K45/06
CPC classification number: A61K38/53 , A61K39/39541 , A61K45/06 , C12N9/93 , C12Y601/01021
Abstract: Inflammatory and other cellular response-modulating compositions are provided comprising aminoacyl-tRNA synthetase polypeptides, including active fragments and/or variants thereof. Also provided are methods of using such compositions in the treatment of conditions that benefit from the modulation of inflammation, such as inflammatory diseases or conditions.
Abstract translation: 提供包含氨基-tRNA合成酶多肽的炎症和其它细胞应答调节组合物,包括其活性片段和/或变体。 还提供了使用这些组合物来治疗受益于炎症疾病或病症等炎症调节的病症的方法。
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公开(公告)号:US20130273045A1
公开(公告)日:2013-10-17
申请号:US13762151
申请日:2013-02-07
Applicant: aTyr Pharma, Inc.
Inventor: Jeffry Dean Watkins , Alain Philippe Vasserot , Leslie Ann Greene , Ryan Andrew Adams , Kyle P. Chiang , Wei Zhang , Kristi Helen Piehl , Fei Hong , Alina He
CPC classification number: A61K38/53 , A61K39/39541 , A61K45/06 , C12N9/93 , C12Y601/01021
Abstract: Inflammatory and other cellular response-modulating compositions are provided comprising aminoacyl-tRNA synthetase polypeptides, including active fragments and/or variants thereof Also provided are methods of using such compositions in the treatment of conditions that benefit from the modulation of inflammation, such as inflammatory diseases or conditions.
Abstract translation: 提供包含氨基-tRNA合成酶多肽,包括活性片段和/或变体的炎症和其他细胞应答调节组合物。还提供了使用这些组合物治疗受益于炎症调节的病症的方法,例如炎性疾病 或条件。
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公开(公告)号:US09943577B2
公开(公告)日:2018-04-17
申请号:US15365079
申请日:2016-11-30
Applicant: aTyr Pharma, Inc.
Inventor: Jeffry Dean Watkins , Alain Philippe Vasserot , Leslie Ann Greene , Ryan Andrew Adams , Kyle P. Chiang , Wei Zhang , Kristi Helen Piehl , Fei Hong , Alina He
CPC classification number: A61K38/53 , A61K39/39541 , A61K45/06 , C12N9/93 , C12Y601/01021
Abstract: Inflammatory and other cellular response-modulating compositions are provided comprising aminoacyl-tRNA synthetase polypeptides, including active fragments and/or variants thereof. Also provided are methods of using such compositions in the treatment of conditions that benefit from the modulation of inflammation, such as inflammatory diseases or conditions.
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公开(公告)号:US20170202933A1
公开(公告)日:2017-07-20
申请号:US15365079
申请日:2016-11-30
Applicant: aTyr Pharma, Inc.
Inventor: Jeffry Dean Watkins , Alain Philippe Vasserot , Leslie Ann Greene , Ryan Andrew Adams , Kyle P. Chiang , Wei Zhang , Kristi Helen Piehl , Fei Hong , Alina He
CPC classification number: A61K38/53 , A61K39/39541 , A61K45/06 , C12N9/93 , C12Y601/01021
Abstract: Inflammatory and other cellular response-modulating compositions are provided comprising aminoacyl-tRNA synthetase polypeptides, including active fragments and/or variants thereof. Also provided are methods of using such compositions in the treatment of conditions that benefit from the modulation of inflammation, such as inflammatory diseases or conditions.
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6.
公开(公告)号:US20150140072A1
公开(公告)日:2015-05-21
申请号:US14541792
申请日:2014-11-14
Applicant: aTyr Pharma, Inc.
Inventor: Jeffry Dean Watkins , Alain Philippe Vasserot , Leslie Ann Greene , Ryan Andrew Adams , Kyle P. Chiang , Wei Zhang , Kristi Helen Piehl , Fei Hong , Alina He
IPC: C12N9/00
CPC classification number: A61K38/53 , A61K39/39541 , A61K45/06 , C12N9/93 , C12Y601/01021
Abstract: Inflammatory and other cellular response-modulating compositions are provided comprising aminoacyl-tRNA synthetase polypeptides, including active fragments and/or variants thereof. Also provided are methods of using such compositions in the treatment of conditions that benefit from the modulation of inflammation, such as inflammatory diseases or conditions.
Abstract translation: 提供包含氨基-tRNA合成酶多肽的炎症和其它细胞应答调节组合物,包括其活性片段和/或变体。 还提供了使用这些组合物来治疗受益于炎症疾病或病症等炎症调节的病症的方法。
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