公开(公告)号：US20240091767A1

公开(公告)日：2024-03-21

申请号：US18082087

申请日：2022-12-15

Applicant: SAMSUNG ELECTRONICS CO, LTD.

Inventor： Jae Hong LEE ,  Won Jong JUNG ,  Kak NAMKOONG ,  Hyeong Seok JANG ,  Jin Ha KIM ,  Hyung Jun YOUN

IPC: B01L3/00 ,  B01L7/00

CPC classification number: B01L3/502715 ,  B01L7/52 ,  B01L2300/0636 ,  B01L2300/0819 ,  B01L2300/12 ,  B01L2300/1861

Abstract: A gene amplification chip includes a chamber layer, a cover layer, a bottom layer, an inlet, and an outlet. The chamber layer has a first passage and through holes which are formed on one side of the first passage. The cover layer is disposed on one side of the chamber layer and has a cover channel formed to communicate with the first passage and the through holes, wherein the cover channel, the first passage and the through holes allow passage of liquids in a divided manner. The bottom layer is disposed on another side of the chamber layer and has a bottom channel formed to communicate with the first passage and the through holes. The inlet is formed in the cover layer and communicates with the cover channel. The outlet communicates with any one of the cover channel and the bottom channel.

公开(公告)号：US20230381772A1

公开(公告)日：2023-11-30

申请号：US17954559

申请日：2022-09-28

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Jae Hong LEE ,  Kak NAMKOONG ,  Hyeong Seok JANG ,  Won Jong JUNG ,  Hyung Jun YOUN

IPC: B01L3/00 ,  B01L7/00

CPC classification number: B01L3/5027 ,  B01L7/52 ,  B01L2200/10 ,  B01L2200/147 ,  B01L2300/1816 ,  B01L2300/0819

Abstract: A gene amplification chip may include: a cover layer having a solution inlet through which a sample solution to be injected; a chamber layer disposed on one surface of the cover layer, and having a chamber to receive the sample solution when the sample solution is injected through the solution inlet such that an amplification reaction of the sample solution occurs in the chamber; a bottom layer disposed on another surface of the chamber layer; and a photothermal film attached to an outer surface of the bottom layer, and configured to convert light into heat to heat the sample solution received in the chamber.

公开(公告)号：US20240280513A1

公开(公告)日：2024-08-22

申请号：US18224325

申请日：2023-07-20

Applicant: SAMSUNG ELECTRONICS CO., LTD. ,  SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Inventor： Jae Hong LEE ,  Jungwon PARK ,  Min-Ho KANG ,  Minyoung LEE ,  Hyeong Seok JANG ,  Won Jong JUNG ,  Jin Ha KIM ,  Kak NAMKOONG ,  Hyung Jun YOUN

IPC: G01N23/06 ,  B81B1/00 ,  B81C1/00 ,  G01N33/483

CPC classification number: G01N23/06 ,  B81B1/002 ,  B81C1/00071 ,  G01N33/483 ,  B81B2201/05 ,  B81B2203/033 ,  B81B2203/0338 ,  B81C2201/0132 ,  B81C2201/0181 ,  B81C2201/0198

Abstract: The present disclosure provides methods and apparatuses for biomaterial detection sensors. In some embodiments, a biomaterial detection sensor includes a membrane including a plurality of wells. Each of the plurality of wells is configured to encapsulate a biomaterial contained in a sample solution. A surface of the membrane is selectively modified into at least one of a hydrophilic surface and a hydrophobic surface. In some embodiments, a method of manufacturing a biomaterial detection sensor includes depositing a first membrane and a second membrane on respective surfaces of a wafer, forming a window by etching the first membrane and the first surface of the wafer, forming a plurality of wells on the second membrane, modifying a surface of the second membrane into at least one of a hydrophilic surface and a hydrophobic surface; and transferring a two-dimensional graphene oxide material onto a bottom of each of the plurality of wells.

公开(公告)号：US20230302447A1

公开(公告)日：2023-09-28

申请号：US17889085

申请日：2022-08-16

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Won Jong JUNG ,  Hyeong Seok JANG ,  Kak NAMKOONG ,  Hyung Jun YOUN ,  Jae Hong LEE

IPC: B01L3/00 ,  B01L7/00 ,  G01N15/06

CPC classification number: B01L3/502715 ,  B01L7/52 ,  G01N15/06 ,  B01L2300/0654 ,  B01L2300/0645 ,  B01L2300/1894 ,  B01L2300/1822 ,  B01L2300/0681 ,  G01N2015/0065

Abstract: An apparatus and method for bio-particle detection are provided. The apparatus for bio-particle detection includes: a bio-particle detection chip including a substrate having a plurality of through-hole groups, each through-hole group of the plurality of through-hole groups including through-holes which pass through the substrate from a first surface of the substrate toward an second surface of the substrate opposite to the first surface, and which are configured to accommodate a sample solution loaded therein; and a processor configured to determine a number of through-holes, among the through holes of at least one through-hole group of the plurality of through-hole groups, having a target material encapsulated therein, based on at least one of an electrical signal and an optical signal corresponding to the through-holes of the at least one through-hole group, and to estimate a concentration of the target material based on the determined number.

公开(公告)号：US20240219282A1

公开(公告)日：2024-07-04

申请号：US18202794

申请日：2023-05-26

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Hyeong Seok JANG ,  Won Jong JUNG ,  Jin Ha KIM ,  Kak NAMKOONG ,  Hyung Jun YOUN ,  Jae Hong LEE

IPC: G01N15/02

CPC classification number: G01N15/0205

Abstract: Provided is an apparatus configured to detect fine particles, including a fine particle trap including a plurality of through holes that are configured to trap the fine particles, a measurer including a light source configured to emit light to the plurality of through holes, and a detector configured to detect light scattered, reflected, or transmitted through the plurality of through holes and measure a spectrum, and a processor configured to estimate a number of the fine particles trapped in the plurality of through holes based on of the measured spectrum, wherein the plurality of through holes have a diameter equal to or less than 10 μm.