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1.发明申请公开(公告)号：US20100131023A1
公开(公告)日：2010-05-27
申请号：US12305894
申请日：2007-06-21
Applicant: Benedict James Costello , Marc Jensen , Mark Zdeblick , Jeremy Frank , Vladimer Gelfandbein , Lawrence Arne
Inventor： Benedict James Costello , Marc Jensen , Mark Zdeblick , Jeremy Frank , Vladimer Gelfandbein , Lawrence Arne
CPC classification number: C23C14/0641 , C04B35/56 , C04B35/5611 , C04B35/5626 , C04B35/58 , C04B38/0022 , C04B2111/00793 , C04B2111/0081 , C04B2111/00836 , C04B2111/00844 , C23C14/0635 , C23C14/0664 , C23C14/325 , H01J37/32055
Abstract: Implantable medical devices that include cathodic arc produced structures are provided. Cathodic arc produced structures of the invention may be thick, stress-free metallic structures that have configurations heretofore not available in implantable medical devices. In yet other embodiments, the structures may be crenulated or porous layers. Also provided are methods of producing implantable medical devices as well as systems for practicing the subject methods.
Abstract translation: 提供了包括阴极电弧产生结构的植入式医疗设备。 本发明的阴极电弧产生的结构可以是厚的，无应力的金属结构，其具有以前在植入式医疗装置中不可用的构造。 在其他实施例中，结构可以是经过弯曲的或多孔的层。 还提供了生产可植入医疗装置的方法以及用于实施本发明方法的系统。
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公开(公告)号：US07073387B2
公开(公告)日：2006-07-11
申请号：US11025795
申请日：2004-12-28
Applicant: Mark Zdeblick , Benedict James Costello
Inventor： Mark Zdeblick , Benedict James Costello
IPC: G01L7/08
CPC classification number: A61B5/0215 , A61B5/412 , A61B2562/02 , A61N1/3627 , A61N1/36564 , G01L9/0042 , G01L9/0055 , G01L9/045 , G01L9/065
Abstract: Implantable pressure sensors and methods for making and using the same. A feature of of at least some of the subject pressure sensors is that they are low-drift sensors. Additional features of representable pressure sensors include the presence of a compliant member mounted on a substrate in a manner such that the compliant member has first and second opposing exposed surfaces and is positioned at least proximal to the said pressure sensor's neutral plane. The subject pressure sensors find use in a variety of applications.
Abstract translation: 可植入压力传感器及其制造和使用方法。 至少一些目标压力传感器的特征在于它们是低漂移传感器。 可表现的压力传感器的附加特征包括以使得柔顺构件具有第一和第二相对的暴露表面并且至少位于所述压力传感器的中立平面附近的方式存在安装在基底上的顺应构件。 主题压力传感器可用于各种应用。
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3.发明授权公开(公告)号：US07007551B2
公开(公告)日：2006-03-07
申请号：US11025879
申请日：2004-12-28
Applicant: Mark Zdeblick , Benedict James Costello
Inventor： Mark Zdeblick , Benedict James Costello
IPC: G01L7/08
CPC classification number: A61B5/0215 , A61B5/412 , A61B2562/02 , A61N1/3627 , A61N1/36564 , G01L9/0042 , G01L9/0055 , G01L9/045 , G01L9/065
Abstract: Implantable pressure sensors and methods for making and using the same. A feature of of at least some of the subject pressure sensors is that they are low-drift sensors. Additional features of representative pressure sensors include the presence of first and second strain transducers that are associated with a compliant member so that their outputs respond oppositely to deflection of the compliant member resulting from differential pressure across the compliant member but respond similarly to deformation of a substrate on which the compliant member is mounted. The subject pressure sensors find use in a variety of applications.
Abstract translation: 可植入压力传感器及其制造和使用方法。 至少一些目标压力传感器的特征在于它们是低漂移传感器。 代表性的压力传感器的附加特征包括存在与柔性构件相关联的第一和第二应变传感器，使得它们的输出与穿过柔性构件的差压产生的柔性构件的偏转相反地反应，但是类似于基底的变形 其上安装有柔性构件。 主题压力传感器可用于各种应用。
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公开(公告)号：US07028550B2
公开(公告)日：2006-04-18
申请号：US11025657
申请日：2004-12-28
Applicant: Mark Zdeblick , Benedict James Costello
Inventor： Mark Zdeblick , Benedict James Costello
IPC: G01L7/08
CPC classification number: A61B5/0215 , A61B5/412 , A61B2562/02 , A61N1/3627 , A61N1/36564 , G01L9/0042 , G01L9/0055 , G01L9/045 , G01L9/065
Abstract: Implantable pressure sensors and methods for making and using the same. A feature of at least some of the subject pressure sensors is that they are low-drift sensors. Additional features of representative pressure sensors include the presence of at least one strain transducer that is fabricated from a stable gauge material. The subject pressure sensors find use in a variety of applications.
Abstract translation: 可植入压力传感器及其制造和使用方法。 至少一些目标压力传感器的特征在于它们是低漂移传感器。 代表性压力传感器的附加特征包括存在由稳定的规格材料制成的至少一个应变换能器。 主题压力传感器可用于各种应用。
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公开(公告)号：US07013734B2
公开(公告)日：2006-03-21
申请号：US11025876
申请日：2004-12-28
Applicant: Mark Zdeblick , Benedict James Costello
Inventor： Mark Zdeblick , Benedict James Costello
IPC: G01L7/08
CPC classification number: A61B5/0215 , A61B5/412 , A61B2562/02 , A61N1/3627 , A61N1/36564 , G01L9/0042 , G01L9/0055 , G01L9/045 , G01L9/065
Abstract: Implantable pressure sensors and methods for making and using the same. A feature of at least some of the subject pressure sensors is that they are low-drift sensors. Additional features of representative pressure sensors include the presence of at least one strain transducer that is fabricated from a stable gauge material. The subject pressure sensors find use in a variety of applications.
Abstract translation: 可植入压力传感器及其制造和使用方法。 至少一些目标压力传感器的特征在于它们是低漂移传感器。 代表性压力传感器的附加特征包括存在由稳定的规格材料制成的至少一个应变换能器。 主题压力传感器可用于各种应用。
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Patent Agency Ranking
公开(公告)号：US07066031B2
公开(公告)日：2006-06-27
申请号：US11025793
申请日：2004-12-28
Applicant: Mark Zdeblick , Benedict James Costello
Inventor： Mark Zdeblick , Benedict James Costello
IPC: G01L7/08
CPC classification number: A61B5/0215 , A61B5/412 , A61B2562/02 , A61N1/3627 , A61N1/36564 , G01L9/0042 , G01L9/0055 , G01L9/045 , G01L9/065
Abstract: Implantable pressure sensors and methods for making and using the same. A feature of at least some of the subject pressure sensors is that they are low-drift sensors. Additional features of representative pressure sensors include the presence of at least one strain transducer that is fabricated from a stable gauge material. The subject pressure sensors find use in a variety of applications.
Abstract translation: 可植入压力传感器及其制造和使用方法。 至少一些目标压力传感器的特征在于它们是低漂移传感器。 代表性压力传感器的附加特征包括存在由稳定的规格材料制成的至少一个应变换能器。 主题压力传感器可用于各种应用。
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7.发明申请公开(公告)号：US20100143232A1
公开(公告)日：2010-06-10
申请号：US12305910
申请日：2007-06-21
Applicant: Benedict James Costello , Jeremy Frank , Vladimier Gelfandbein
Inventor： Benedict James Costello , Jeremy Frank , Vladimier Gelfandbein
CPC classification number: C23C14/0641 , C04B35/56 , C04B35/5611 , C04B35/5626 , C04B35/58 , C04B38/0022 , C04B2111/00793 , C04B2111/0081 , C04B2111/00836 , C04B2111/00844 , C23C14/0635 , C23C14/0664 , C23C14/325 , H01J37/32055
Abstract: The present invention allows the relatively easy production of binary and ternary compounds of metals, including noble metals. Embodiments of the invention allow, for the first time, the production of novel compositions of metal compounds, such as thick, stress-free single-phase binary and ternary compositions of metals, and porous compositions of such compounds. As such, the present invention allows for the production of metal compounds and/or compositions of matter thereof that have not before been possible, thereby providing for important new materials that find use in a multitude of different applications, including medical device and non-medical device applications.
Abstract translation: 本发明允许相对容易地生产包括贵金属的金属二元和三元化合物。 本发明的实施方案首次允许生产金属化合物的新组合物，例如厚的，无应力的单相二元和三元金属组合物，以及这些化合物的多孔组合物。 因此，本发明允许生产尚未成为可能的金属化合物和/或其物质组合物，从而提供可用于多种不同应用的重要新材料，包括医疗器械和非医用 设备应用程序。
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8.发明授权公开(公告)号：US08036743B2
公开(公告)日：2011-10-11
申请号：US11909786
申请日：2006-03-31
Applicant: George M. Savage , Todd Thompson , Mark J. Zdeblick , Lawrence W. Arne , Olivier Colliou , Benedict James Costello , Fataneh A. Omidvar
Inventor： George M. Savage , Todd Thompson , Mark J. Zdeblick , Lawrence W. Arne , Olivier Colliou , Benedict James Costello , Fataneh A. Omidvar
IPC: A61N1/39
CPC classification number: A61N1/3627 , A61N1/08 , A61N1/36185 , A61N1/36564 , A61N1/36571 , A61N1/36578 , A61N1/3686 , A61N1/37247
Abstract: One embodiment of the present invention provides a system for automatically optimizing CRT procedures using a multi-electrode pacing lead. During operation, the system performs a first set of iterations to select one or more satellites on one or more pacing leads inserted in a patient. A pacing lead includes a plurality of pacing satellites, and a pacing satellite includes a plurality of electrodes that can be individually addressed and used for transmitting or detecting electric signals. The system then performs a second set of iterations to select one or more electrodes on the selected satellites. The system further performs a third set of iterations to select one or more timing configurations for pacing signals transmitted through one or more of the selected electrodes.
Abstract translation: 本发明的一个实施例提供一种用于使用多电极起搏引线自动优化CRT程序的系统。 在操作期间，系统执行第一组迭代以在插入患者体内的一个或多个起搏引线上选择一个或多个卫星。 起搏引线包括多个起搏卫星，并且起搏卫星包括多个电极，其可单独寻址并用于发送或检测电信号。 然后，系统执行第二组迭代以选择所选卫星上的一个或多个电极。 该系统进一步执行第三组迭代以选择一个或多个定时配置，用于通过一个或多个所选择的电极传输的起搏信号。
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公开(公告)号：US08961412B2
公开(公告)日：2015-02-24
申请号：US12238345
申请日：2008-09-25
Applicant: Hooman Hafezi , Benedict James Costello , Timothy L. Robertson , Maria Casillas Holen
Inventor： Hooman Hafezi , Benedict James Costello , Timothy L. Robertson , Maria Casillas Holen
IPC: A61B5/07 , A61B5/00 , H04B13/00 , A61B5/145 , H01Q1/22 , H01Q1/27 , H01Q9/16 , H01B1/00 , H04B3/00 , H01Q1/00
CPC classification number: A61B5/073 , A61B5/0002 , A61B5/0028 , A61B5/028 , A61B5/14539 , A61B5/14546 , A61B2562/02 , A61B2562/162 , A61B2562/182 , H01Q1/2208 , H01Q1/273 , H01Q9/16 , H04B13/005 , Y10S128/902
Abstract: Virtual dipole signal amplification for in-body devices, such as implantable and ingestible devices, is provided. Aspects of the in-body deployable antennas of the invention include antennas configured to go from a first configuration to a second configuration following placement in a living body, e.g., via ingestion or implantation. Embodiments of the in-body devices are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.
Abstract translation: 提供了诸如可植入和可摄取装置的体内装置的虚拟偶极子信号放大。 本发明的体内可展开天线的方面包括配置成在放置在生物体中（例如通过摄取或植入）之后从第一配置转变为第二配置的天线。 身体内装置的实施例被配置为在与目标生理部位接触时发出可检测信号。 还提供了制造和使用本发明的装置的方法。
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10.发明申请Automated Optimization of Multi-Electrode Pacing for Cardiac Resynchronization 有权用于心脏再同步的多电极起搏的自动优化公开(公告)号：US20080294218A1
公开(公告)日：2008-11-27
申请号：US11909786
申请日：2006-03-31
Applicant: George M. Savage , Todd Thompson , Mark J. Zdeblick , Lawrence W. Arne , Olivier Colliou , Benedict James Costello , Fataneh A. Omidvar
Inventor： George M. Savage , Todd Thompson , Mark J. Zdeblick , Lawrence W. Arne , Olivier Colliou , Benedict James Costello , Fataneh A. Omidvar
IPC: A61N1/06
CPC classification number: A61N1/3627 , A61N1/08 , A61N1/36185 , A61N1/36564 , A61N1/36571 , A61N1/36578 , A61N1/3686 , A61N1/37247
Abstract: One embodiment of the present invention provides a system for automatically optimizing CRT procedures using a multi-electrode pacing lead. During operation, the system performs a first set of iterations to select one or more satellites on one or more pacing leads inserted in a patient. A pacing lead includes a plurality of pacing satellites, and a pacing satellite includes a plurality of electrodes that can be individually addressed and used for transmitting or detecting electric signals. The system then performs a second set of iterations to select one or more electrodes on the selected satellites. The system further performs a third set of iterations to select one or more timing configurations for pacing signals transmitted through one or more of the selected electrodes.
Abstract translation: 本发明的一个实施例提供一种用于使用多电极起搏引线自动优化CRT程序的系统。 在操作期间，系统执行第一组迭代以在插入患者体内的一个或多个起搏引线上选择一个或多个卫星。 起搏引线包括多个起搏卫星，并且起搏卫星包括多个电极，其可单独寻址并用于发送或检测电信号。 然后，系统执行第二组迭代以选择所选卫星上的一个或多个电极。 该系统进一步执行第三组迭代以选择一个或多个定时配置，用于通过一个或多个所选择的电极发射的起搏信号。
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