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公开(公告)号：US20220257567A1
公开(公告)日：2022-08-18
申请号：US17625327
申请日：2021-04-27
Inventor： Sang Yup LEE , Woo Dae JANG , Seungtaek KIM , Sangeun JEON
IPC: A61K31/4184 , A61K31/519 , A61K45/06 , A61K31/444
Abstract: The present invention relates to a pharmaceutical composition for preventing or treating coronavirus disease 2019, and more specifically to a pharmaceutical composition for preventing or treating coronavirus disease 2019 found by drug repositioning technology using drug virtual screening technology. The pharmaceutical composition for preventing or treating coronavirus disease 2019 according to the present invention is a composition obtained by finding new uses for drugs, which have already been proven effective, for preventing or treating coronavirus disease 2019 by drug repositioning technology. The pharmaceutical composition is useful because it has significantly lower side effects than new drugs and can be rapidly applied to clinical practice.
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公开(公告)号：US20240102068A1
公开(公告)日：2024-03-28
申请号：US18263127
申请日：2022-01-27
Inventor： Sang Yup LEE , Dongsoo YANG , Woo Dae JANG
CPC classification number: C12P19/44 , C12N9/0004 , C12N9/1025 , C12N9/1288 , C12N9/16 , C12N9/93 , C12Y207/08007 , C12Y301/04052 , C12Y604/01002
Abstract: The present invention relates to novel C-glycosyltransferase variants and a use thereof. The C-glycosyltransferase variants according to the present invention have improved glycosidic bond-forming ability as compared with wild-type C-glycosyltransferase, and thus can increase the glycoside production effects of polyketide groups and pseudo-natural products, particularly type I, II, III polyketide, nonribosomal peptides, phenylpropanoids, and other aromatic natural products, and thus can be useful for the preparation of a drug, a food additive, a nutritional supplement, and the like containing a C-glycoside compound as a constituent ingredient.
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