公开(公告)号：US20250003949A1

公开(公告)日：2025-01-02

申请号：US18739556

申请日：2024-06-11

Applicant: Hamamatsu Photonics K.K.

Inventor： Tokio TAKAGI ,  Toyohiko YAMAUCHI ,  Tatsuo DOUGAKIUCHI ,  Yoichi KAWADA ,  Yoshiyuki SHIMIZU ,  Gen TAKEBE

IPC: G01N33/483 ,  G01N1/28 ,  G01N1/30 ,  G01N21/64

Abstract: A cell sample measurement apparatus includes a sample stage for placing an object cell sample containing a plurality of cells cultured on a culture dish, an evaluation light irradiation unit for irradiating N irradiation regions set by dividing a culture region in the object cell sample with evaluation light having a wavelength in a mid-infrared region with irradiation amounts different from each other, a dead cell number measurement unit for measuring a dead cell number generated according to the irradiation amount of the evaluation light in each of the N irradiation regions, and a culture state analysis unit for obtaining, for the object cell sample, an object correlation between the irradiation amount of the evaluation light and the dead cell number for the N irradiation regions serving as an index of evaluation of a culture state of the object cell sample.

公开(公告)号：US20250002836A1

公开(公告)日：2025-01-02

申请号：US18739573

申请日：2024-06-11

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Tokio TAKAGI ,  Toyohiko YAMAUCHI ,  Tatsuo DOUGAKIUCHI ,  Yoichi KAWADA ,  Yoshiyuki SHIMIZU ,  Gen TAKEBE

IPC: C12M1/34 ,  C12M1/00 ,  G01N1/30 ,  G01N21/25

Abstract: A cell sample evaluation apparatus includes an evaluation light irradiation unit for irradiating an irradiation region set in a culture region of a plurality of cells in an object cell sample with evaluation light having a wavelength in a mid-infrared region under a predetermined irradiation condition, a dead cell number measurement unit for measuring a dead cell number generated according to an irradiation amount of the evaluation light in the irradiation region of the object cell sample, and a culture state analysis unit for evaluating a culture state of the object cell sample by obtaining an object correlation between the irradiation amount of the evaluation light and the dead cell number for the object cell sample and comparing a reference correlation between the irradiation amount of the evaluation light and the dead cell number for a reference cell sample and the object correlation.