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公开(公告)号：US11090304B2
公开(公告)日：2021-08-17
申请号：US16402538
申请日：2019-05-03
Applicant: Amgen Inc.
Inventor： John Gordon Allen , Jennifer Rebecca Allen , Ana Elena Minatti , Qiufen Xue , Ryan Paul Wurz , Christopher M. Tegley , Alexander J. Pickrell , Thomas T. Nguyen , Vu Van Ma , Patricia Lopez , Longbin Liu , David John Kopecky , Michael J. Frohn , Ning Chen , Jian Jeffrey Chen , Aaron C. Siegmund , Albert Amegadzie , Nuria A. Tamayo , Shon Booker , Clifford Goodman , Mary Walton , Nobuko Nishimura , Youngsook Shin , Jonathan D. Low , Victor J. Cee , Anthony B. Reed , Hui-Ling Wang , Brian Alan Lanman
IPC: A61K31/517 , A61P35/00 , A61K31/4985 , A61K39/395 , C07D403/04 , C07D471/04
Abstract: Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.
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Patent Agency Ranking
公开(公告)号：US10519146B2
公开(公告)日：2019-12-31
申请号：US15984855
申请日：2018-05-21
Applicant: Amgen Inc.
Inventor： Brian Alan Lanman , Jian Chen , Anthony B. Reed , Victor J. Cee , Longbin Liu , David John Kopecky , Patricia Lopez , Ryan Paul Wurz , Thomas T. Nguyen , Shon Booker , Nobuko Nishimura , Youngsook Shin , Nuria A. Tamayo , John Gordon Allen , Jennifer Rebecca Allen
IPC: C07D471/04 , C07D487/04 , C07D403/04 , C07D401/04 , C07D475/00 , A61K31/496 , A61K31/519 , A61P35/00 , C07D417/04 , A61K38/07 , C07D487/08 , C07D417/12 , C07D513/04 , C07D487/10 , C07D239/80 , C07D401/14 , C07D237/34 , A61K31/416 , A61K31/55 , A61K31/454 , A61K31/517 , A61K31/502 , A61K31/5025 , A61K31/7068 , C07D275/04
Abstract: Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.
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公开(公告)号：US12083121B2
公开(公告)日：2024-09-10
申请号：US17579359
申请日：2022-01-19
Applicant: AMGEN INC.
Inventor： John Gordon Allen , Brian Alan Lanman , Jian Chen , Anthony B. Reed , Victor J. Cee , Longbin Liu , Patricia Lopez , Ryan Paul Wurz , Thomas T. Nguyen , Shon Booker , Jennifer Rebecca Allen , Margaret Chu-Moyer , Albert Amegadzie , Ning Chen , Clifford Goodman , Jonathan D. Low , Vu Van Ma , Ana Elena Minatti , Nobuko Nishimura , Alexander J. Pickrell , Hui-Ling Wang , Youngsook Shin , Aaron C. Siegmund , Kevin C. Yang , Nuria A. Tamayo , Mary Walton , Qiufen Xue
IPC: C07D241/04 , A61K31/519 , A61K31/551 , A61K39/395 , A61P35/00
CPC classification number: A61K31/519 , A61K31/551 , A61K39/39558 , A61P35/00
Abstract: Provided herein are KRAS G12C inhibitors, such as
composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.-
公开(公告)号：US11766436B2
公开(公告)日：2023-09-26
申请号：US17363878
申请日：2021-06-30
Applicant: Amgen Inc.
Inventor： John Gordon Allen , Jennifer Rebecca Allen , Ana Elena Minatti , Qiufen Xue , Ryan Paul Wurz , Christopher M. Tegley , Alexander J. Pickrell , Thomas T. Nguyen , Vu Van Ma , Patricia Lopez , Longbin Liu , David John Kopecky , Michael J. Frohn , Ning Chen , Jian Jeffrey Chen , Aaron C. Siegmund , Albert Amegadzie , Nuria A. Tamayo , Shon Booker , Clifford Goodman , Mary Walton , Nobuko Nishimura , Youngsook Shin , Jonathan D. Low , Victor J. Cee , Anthony B. Reed , Hui-Ling Wang , Brian Alan Lanman
IPC: A61K31/517 , A61P35/00 , A61K31/4985 , A61K39/395 , C07D403/04 , C07D471/04
CPC classification number: A61K31/517 , A61K31/4985 , A61K39/39558 , A61P35/00 , C07D403/04 , C07D471/04
Abstract: Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.
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公开(公告)号：US11285156B2
公开(公告)日：2022-03-29
申请号：US16438349
申请日：2019-06-11
Applicant: Amgen Inc.
Inventor： John Gordon Allen , Brian Alan Lanman , Jian Chen , Anthony B. Reed , Victor J. Cee , Longbin Liu , Patricia Lopez , Ryan Paul Wurz , Thomas T. Nguyen , Shon Booker , Jennifer Rebecca Allen , Margaret Chu-Moyer , Albert Amegadzie , Ning Chen , Clifford Goodman , Jonathan D. Low , Vu Van Ma , Ana Elena Minatti , Nobuko Nishimura , Alexander J. Pickrell , Hui-Ling Wang , Youngsook Shin , Aaron C. Siegmund , Kevin C. Yang , Nuria A. Tamayo , Mary Walton , Qiufen Xue
IPC: A61K31/497 , C07D241/04 , A61K31/519 , A61K31/551 , A61K39/395 , A61P35/00
Abstract: Provided herein are KRAS G12C inhibitors, such as composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.
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公开(公告)号：US11905281B2
公开(公告)日：2024-02-20
申请号：US17031607
申请日：2020-09-24
Applicant: Amgen Inc.
Inventor： Brian Alan Lanman , Jian Chen , Anthony B. Reed , Victor J. Cee , Longbin Liu , David John Kopecky , Patricia Lopez , Ryan Paul Wurz , Thomas T. Nguyen , Shon Booker , Nobuko Nishimura , Youngsook Shin , Nuria A. Tamayo , John Gordon Allen , Jennifer Rebecca Allen
IPC: C07D471/04 , C07D213/82 , C07D417/04 , A61K38/07 , C07D487/08 , C07D417/12 , C07D513/04 , C07D487/10 , C07D487/04 , C07D401/04 , C07D239/80 , C07D401/14 , C07D237/34 , C07D403/04 , A61K31/496 , A61K31/416 , A61K31/55 , A61K31/454 , A61K31/519 , A61K31/502 , A61K31/517 , A61K31/5025 , A61P35/00 , A61K31/7068 , C07D275/04 , C07D475/00
CPC classification number: C07D417/04 , A61K31/416 , A61K31/454 , A61K31/496 , A61K31/502 , A61K31/5025 , A61K31/517 , A61K31/519 , A61K31/55 , A61K31/7068 , A61K38/07 , A61P35/00 , C07D237/34 , C07D239/80 , C07D275/04 , C07D401/04 , C07D401/14 , C07D403/04 , C07D417/12 , C07D471/04 , C07D475/00 , C07D487/04 , C07D487/08 , C07D487/10 , C07D513/04
Abstract: Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.
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