公开(公告)号：US20210093789A1

公开(公告)日：2021-04-01

申请号：US17036556

申请日：2020-09-29

Applicant: AMGEN INC.

Inventor： Christian Plambech ,  Matias Melander ,  Bjarke Lykke Ludvig Svendsen ,  Joshua Jay Dudman ,  Michael Sorensen ,  Margaux Frances Boyaval ,  Avon Kuo

IPC: A61M5/315 ,  A61M5/20

Abstract: Drug delivery devices and related arrangements are disclosed. A drug delivery device may include a housing having an opening, a drug storage container including a delivery member with an insertion end configured to extend at least partially through the opening, and a plunger. A drive mechanism may be included for driving the plunger in a distal direction to expel a drug from the drug storage container through the delivery member upon activation. The drug delivery device may additionally include a guard moveably disposed adjacent to the opening and operably coupled to the drive mechanism for activation of the drive mechanism. A lock may be selectively engageable with the guard to limit movement of the guard in the proximal direction. An indicator may be coupled to the drive mechanism to generate an audible signal during drug delivery, and to cease generating the audible signal when drug delivery is complete.

公开(公告)号：US12102808B2

公开(公告)日：2024-10-01

申请号：US17036556

申请日：2020-09-29

Applicant: AMGEN INC.

Inventor： Christian Plambech ,  Matias Melander ,  Bjarke Lykke Ludvig Svendsen ,  Joshua Jay Dudman ,  Michael Sorensen ,  Margaux Frances Boyaval ,  Avon Kuo

IPC: A61M5/315 ,  A61M5/20 ,  A61M5/32

CPC classification number: A61M5/3157 ,  A61M5/2033 ,  A61M5/3204 ,  A61M2205/581

Abstract: Drug delivery devices and related arrangements are disclosed. A drug delivery device may include a housing having an opening, a drug storage container including a delivery member with an insertion end configured to extend at least partially through the opening, and a plunger. A drive mechanism may be included for driving the plunger in a distal direction to expel a drug from the drug storage container through the delivery member upon activation. The drug delivery device may additionally include a guard moveably disposed adjacent to the opening and operably coupled to the drive mechanism for activation of the drive mechanism. A lock may be selectively engageable with the guard to limit movement of the guard in the proximal direction. An indicator may be coupled to the drive mechanism to generate an audible signal during drug delivery, and to cease generating the audible signal when drug delivery is complete.

公开(公告)号：US20210369982A1

公开(公告)日：2021-12-02

申请号：US17256249

申请日：2019-07-23

Applicant: AMGEN INC.

Inventor： Margaux Frances Boyaval ,  Brian Stonecipher ,  Avon Kuo ,  James Chan ,  Lisa Nugent

IPC: A61M5/42 ,  A61M5/32 ,  A61M5/20

Abstract: Delivery devices for administering drugs are disclosed. An example apparatus, includes a body including: a handle in which a syringe assembly is to be disposed; a base having a bottom face to be disposed adjacent a user; and an absorbent material attached to the bottom face, the absorbent material structured to hold a fluid to be released onto the user prior to or during an injection procedure.

公开(公告)号：US20210260279A1

公开(公告)日：2021-08-26

申请号：US17256241

申请日：2019-07-11

Applicant: AMGEN INC.

Inventor： Margaux Frances Boyaval ,  Brian Stonecipher ,  Avon Kuo ,  Lisa Nugent

IPC: A61M5/142 ,  A61M5/162

Abstract: Drug delivery devices are described that provide hybrid forms with optional gripping functionalities. For example, the devices can include a grip portion on a skin contact surface with a release liner disposed thereon. A user can operate the devices with the release liner disposed on the grip portion or can remove the release liner so that the grip portion is able to aid users in orienting and supporting the device during an injection operation.

公开(公告)号：US20250108172A1

公开(公告)日：2025-04-03

申请号：US18891521

申请日：2024-09-20

Applicant: AMGEN INC.

Inventor： Margaux Frances Boyaval ,  Brian Stonecipher ,  Avon Kuo ,  James Chan ,  Lisa Nugent

IPC: A61M5/32 ,  A61M5/20 ,  A61M5/31

Abstract: Drug delivery devices are described that provide hybrid forms with gripping and stability functionalities, such as a grip portion on a skin contact surface. In some versions, the drug delivery devices can include a cap having a release liner such that removal of the cap exposes the grip portion. In some versions, the drug delivery devices include a retractable needle guard having the grip portion extending therearound.

公开(公告)号：US11590277B2

公开(公告)日：2023-02-28

申请号：US16488120

申请日：2018-03-06

Applicant: AMGEN INC.

Inventor： Brian Stonecipher ,  Margaux Frances Boyaval ,  James Chan ,  Avon Kuo ,  Allan Lee Cameron ,  Maxwell Franklin Bischoff ,  Gregg Allen Flender

IPC: A61M5/14 ,  A61M5/142

Abstract: A wearable drug delivery device includes an injector having a housing, a reservoir, a needle or cannula, a drive mechanism for urging drug product out of the reservoir, through the needle or cannula, and to a patient, and an activator mechanism disposed on a surface of the housing for activating the drive mechanism. An activation prevention mechanism is coupled to the injector housing and/or activation prevention mechanism to prevent inadvertent actuation of the activator mechanism.

公开(公告)号：US20190381238A1

公开(公告)日：2019-12-19

申请号：US16488120

申请日：2018-03-06

Applicant: AMGEN INC.

Inventor： Brian Stonecipher ,  Margaux Frances Boyaval ,  James Chan ,  Avon Kuo ,  Allan Lee Cameron ,  Maxwell Franklin Bischoff ,  Gregg Allen Flender

IPC: A61M5/14 ,  A61M5/142

Abstract: A wearable drug delivery device includes an injector having a housing, a reservoir, a needle or cannula, a drive mechanism for urging drug product out of the reservoir, through the needle or cannula, and to a patient, and an activator mechanism disposed on a surface of the housing for activating the drive mechanism. An activation prevention mechanism is coupled to the injector housing and/or activation prevention mechanism to prevent inadvertent actuation of the activator mechanism.

公开(公告)号：US20240390599A1

公开(公告)日：2024-11-28

申请号：US18789085

申请日：2024-07-30

Applicant: AMGEN INC.

Inventor： Christian Plambech ,  Matias Melander ,  Bjarke Lykke Ludvig Svendsen ,  Joshua Jay Dudman ,  Michael Sorensen ,  Margaux Frances Boyaval ,  Avon Kuo

IPC: A61M5/315 ,  A61M5/20 ,  A61M5/32

Abstract: Drug delivery devices and related arrangements are disclosed. A drug delivery device may include a housing having an opening, a drug storage container including a delivery member with an insertion end configured to extend at least partially through the opening, and a plunger. A drive mechanism may be included for driving the plunger in a distal direction to expel a drug from the drug storage container through the delivery member upon activation. The drug delivery device may additionally include a guard moveably disposed adjacent to the opening and operably coupled to the drive mechanism for activation of the drive mechanism. A lock may be selectively engageable with the guard to limit movement of the guard in the proximal direction. An indicator may be coupled to the drive mechanism to generate an audible signal during drug delivery, and to cease generating the audible signal when drug delivery is complete.

公开(公告)号：US12115360B2

公开(公告)日：2024-10-15

申请号：US17256243

申请日：2019-07-22

Applicant: AMGEN INC.

Inventor： Margaux Frances Boyaval ,  Brian Stonecipher ,  Avon Kuo ,  James Chan ,  Lisa Nugent

IPC: A61M5/32 ,  A61M5/20 ,  A61M5/31

CPC classification number: A61M5/3204 ,  A61M5/20 ,  A61M2005/2013 ,  A61M2005/208 ,  A61M2005/3107

Abstract: Drug delivery devices are described that provide hybrid forms with gripping and stability functionalities, such as a grip portion on a skin contact surface. In some versions, the drug delivery devices can include a cep having a release liner such that removal of the cap exposes the grip portion. In some versions, the drug delivery devices include a retractable needle guard having the grip portion extending therearound.

公开(公告)号：US12042645B2

公开(公告)日：2024-07-23

申请号：US17256249

申请日：2019-07-23

Applicant: AMGEN INC.

Inventor： Margaux Frances Boyaval ,  Brian Stonecipher ,  Avon Kuo ,  James Chan ,  Lisa Nugent

IPC: A61M5/42 ,  A61M5/20 ,  A61M5/32

CPC classification number: A61M5/422 ,  A61M5/20 ,  A61M5/2033 ,  A61M5/3202 ,  A61M2005/2013 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2205/0205 ,  A61M2205/10 ,  A61M2205/586

Abstract: Delivery devices for administering drugs are disclosed. An example apparatus, includes a body including: a handle in which a syringe assembly is to be disposed; a base having a bottom face to be disposed adjacent a user; and an absorbent material attached to the bottom face, the absorbent material structured to hold a fluid to be released onto the user prior to or during an injection procedure.