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公开(公告)号：US20230008122A1
公开(公告)日：2023-01-12
申请号：US17855383
申请日：2022-06-30
Applicant: Alcon Inc.
Inventor： John Alfred Campin , Martin Gründig , Victor Manuel Hernandez , George Hunter Pettit , Mark Andrew Zielke , Daniil Nekrassov
Abstract: A system for selecting a preferred intraocular lens for implantation into an eye includes a controller having a processor and a tangible, non-transitory memory. The controller is configured to obtain diagnostic data of the eye, and obtain historical data composed of historical sets of patient data. The controller is configured to analyze individual risk factors based on the diagnostic data and obtain a weighted combination of the individual risk factors. A respective satisfaction metric for the plurality of intraocular lenses is generated based on the historical data. A preferred intraocular lens may be selected based in part on the respective satisfaction metric and the weighted combination. A visual simulation for each of the plurality of intraocular lenses may be performed, based in part on the diagnostic data. The visual simulation may incorporate an impact of the tear film data.
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公开(公告)号：US20210369106A1
公开(公告)日：2021-12-02
申请号：US17330327
申请日：2021-05-25
Applicant: Alcon Inc.
Inventor： John Alfred Campin , Brant Gillen , Martin Gründig , Robert Moore , George Hunter Pettit , Mark Andrew Zielke
Abstract: A system and method for selecting an intraocular lens, for implantation into an eye, includes a controller having a processor and a tangible, non-transitory memory on which instructions are recorded. The controller is configured to selectively execute a machine learning model trained with a training dataset. Execution of the instructions by the processor causes the controller to obtain pre-operative objective data for the patient, including one or more anatomic eye measurements. The controller is configured to obtain pre-operative questionnaire data for the patient, including at least one personality trait. The pre-operative objective data and the pre-operative questionnaire data are entered as respective inputs to the machine learning model. A predicted subjective outcome score for the patient is generated as an output of the machine learning model. The intraocular lens is selected based in part on the predicted subjective outcome score.
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公开(公告)号：US20250143565A1
公开(公告)日：2025-05-08
申请号：US18934491
申请日：2024-11-01
Applicant: Alcon Inc.
Inventor： Chad P. Byers , Mark Andrew Zielke , Christopher Sean Mudd
Abstract: A system and method for visualizing an eye using an optical coherence tomography (“OCT”) device includes a controller having a processor and a tangible, non-transitory memory on which instructions are recorded. The OCT device produces an OCT beam defined by an OCT beam axis. The controller is adapted to receive a first dataset captured with the OCT beam axis at a first tilt angle from a first visual axis. The controller is adapted to receive a second dataset captured with the OCT beam axis at a second tilt angle from a second visual axis. A plurality of lens segments is generated based on the first dataset and the second dataset. The controller is adapted to generate a lens profile based in part on the plurality of lens segments.
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公开(公告)号：US20250113993A1
公开(公告)日：2025-04-10
申请号：US18987705
申请日：2024-12-19
Applicant: Alcon Inc.
Inventor： George Hunter Pettit , Daniil Nekrassov , Peter Zieger , Martin Gründig , Horia Grecu , Mark Andrew Zielke , John Alfred Campin
Abstract: An ophthalmic system for generating an ocular model of an eye includes an optical coherence tomography (OCT) device, an aberrometer, and a computer. The OCT device detects OCT light reflected from the eye. The aberrometer detects aberrometer light reflected from the eye. The computer generates the ocular model of the eye according to the reflected OCT light. The ocular model includes parameters describing the eye. The parameters include lens parameters that describe the lens of the eye. The computer determines an OCT-based wavefront according to the ocular model, determines an aberrometer-based wavefront according to the reflected aberrometer light, and compares the OCT-based and the aberrometer-based wavefronts. If the wavefronts differ beyond a predefined tolerance, the computer adjusts one or more values assigned to the parameters until the wavefronts satisfy the predefined tolerance. At least one adjusted value is assigned to a lens parameter.
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公开(公告)号：US12207871B2
公开(公告)日：2025-01-28
申请号：US17574667
申请日：2022-01-13
Applicant: Alcon Inc.
Inventor： George Hunter Pettit , Daniil Nekrassov , Peter Zieger , Martin Gründig , Horia Grecu , Mark Andrew Zielke , John Alfred Campin
Abstract: An ophthalmic system for generating an ocular model of an eye includes an optical coherence tomography (OCT) device, an aberrometer, and a computer. The OCT device detects OCT light reflected from the eye. The aberrometer detects aberrometer light reflected from the eye. The computer generates the ocular model of the eye according to the reflected OCT light. The ocular model includes parameters describing the eye. The parameters include lens parameters that describe the lens of the eye. The computer determines an OCT-based wavefront according to the ocular model, determines an aberrometer-based wavefront according to the reflected aberrometer light, and compares the OCT-based and the aberrometer-based wavefronts. If the wavefronts differ beyond a predefined tolerance, the computer adjusts one or more values assigned to the parameters until the wavefronts satisfy the predefined tolerance. At least one adjusted value is assigned to a lens parameter.
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Patent Agency Ranking
6.发明申请公开(公告)号：US20220331092A1
公开(公告)日：2022-10-20
申请号：US17722921
申请日：2022-04-18
Applicant: Alcon Inc.
Inventor： John Alfred Campin , Horia Grecu , George Hunter Pettit , Mark Andrew Zielke , Peter Zieger
Abstract: Certain aspects of the present disclosure provide techniques for performing surgical ophthalmic procedures, such as cataract surgeries. An example method generally includes generating, using one or more measurement devices, one or more data points associated with measurements of one or more anatomical parameters for an eye to be treated. Using one or more trained machine learning models, one or more recommendations are generated including one or more IOL parameters for the IOL to be used in the cataract surgery based, at least in part, on the one or more data points. The machine learning models are trained based on at least one historical data set of data points associated with measurements of anatomical parameters mapped to treatment data and treatment result data associated with each historical patient. The one or more IOL parameters comprise one or more of an IOL type, an IOL power, or IOL placement information for implanting the IOL in the eye.
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公开(公告)号：US12089894B2
公开(公告)日：2024-09-17
申请号：US17501894
申请日：2021-10-14
Applicant: ALCON INC.
Inventor： George Hunter Pettit , Mark Andrew Zielke , Victor Manuel Hernandez , Philip Matthew McCulloch
CPC classification number: A61B3/0025 , A61B3/0008 , A61B3/103 , A61B3/112
Abstract: A system for predicting post-operative vignetting in an eye of a subject includes a controller having a processor and a tangible, non-transitory memory on which instructions are recorded. The controller is in communication with a diagnostic module adapted to store pre-operative anatomic data of the eye as an eye model. The system includes a projection module and a ray tracing module selectively executable by the controller. The projection module is adapted to determine imputed post-operative variables of the eye based at least partially on the pre-operative anatomic data and the intraocular lens. The ray tracing module is adapted to calculate propagation of light through the eye. The ray tracing module is executed to determine a light distribution for respective visual field angles across a predefined field of view. The controller is configured to determine one or more post-operative vignetting parameters based at least partially on the light distribution.
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公开(公告)号：US12070270B2
公开(公告)日：2024-08-27
申请号：US17507659
申请日：2021-10-21
Applicant: Alcon Inc.
Inventor： John Alfred Campin , Martin Gründig , Armin Haupt , George Hunter Pettit , Mark Andrew Zielke
CPC classification number: A61B3/113 , A61B3/0025
Abstract: A method for assessing a lens capsule stability condition in an eye of a human patient includes directing electromagnetic energy in a predetermined spectrum onto a pupil of the eye, via an energy source, concurrently subsequent to a movement of the eye causing eye saccades to occur therein. The method also includes acquiring images of the eye indicative of the eye saccades using an image capture device, and computing, via the ECU, a motion curve of the lens capsule using the images. Additionally, the method includes extracting time-normalized lens capsule oscillation traces based on the motion curve via the ECU, and then model-fitting the lens capsule oscillation traces via the ECU to thereby assess the lens capsule instability condition. An automated system for performing an embodiment of the method is also disclosed herein, including the energy source, image capture device, and ECU.
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公开(公告)号：US11998445B2
公开(公告)日：2024-06-04
申请号：US16905738
申请日：2020-06-18
Applicant: Alcon Inc.
Inventor： Mark Andrew Zielke
IPC: A61F2/16
CPC classification number: A61F2/167 , A61F2/1678 , A61F2002/1683 , A61F2002/16905
Abstract: Systems, methods, and devices for inserting an intraocular lens (IOL) assembly into an eye may be provided. An apparatus for delivery of a lens component into an eye may include a housing. The apparatus may further include a plunger at least partially disposed in the housing, wherein the housing comprises an elongated portion and a viscoelastic soft tip at a distal end of the elongated portion, wherein the viscoelastic soft tip has a storage modulus of about 1 megapascal (MPa) to about 300 MPa and a loss module of about 1 MPa to about 300 MPa. The apparatus may further include a drive mechanism operatively coupled to plunger and configured to cause the plunger to translate in the housing. The apparatus may further include a nozzle operatively coupled to the housing through which the plunger delivers the lens component into the eye.
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公开(公告)号：US20210007841A1
公开(公告)日：2021-01-14
申请号：US16905738
申请日：2020-06-18
Applicant: Alcon Inc.
Inventor： Mark Andrew Zielke
IPC: A61F2/16
Abstract: Systems, methods, and devices for inserting an intraocular lens (IOL) assembly into an eye may be provided. An apparatus for delivery of a lens component into an eye may include a housing. The apparatus may further include a plunger at least partially disposed in the housing, wherein the housing comprises an elongated portion and a viscoelastic soft tip at a distal end of the elongated portion, wherein the viscoelastic soft tip has a storage modulus of about 1 megapascal (MPa) to about 300 MPa and a loss module of about 1 MPa to about 300 MPa. The apparatus may further include a drive mechanism operatively coupled to plunger and configured to cause the plunger to translate in the housing. The apparatus may further include a nozzle operatively coupled to the housing through which the plunger delivers the lens component into the eye.
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