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公开(公告)号：US12053631B2
公开(公告)日：2024-08-06
申请号：US17318824
申请日：2021-05-12
申请人： ELECTROCORE, INC
发明人： Bruce J. Simon , Joseph P. Errico
CPC分类号： A61N1/36021 , A61B5/394 , A61B5/4035 , A61B5/4041 , A61B5/4803 , A61B5/4836 , A61B5/7264 , A61B5/7267 , A61N1/0456 , A61N1/36031 , A61N1/36034 , A61B5/02405 , A61B2090/3941 , A61N1/40
摘要： Methods for treating medical disorders, such as migraine or other primary headaches, or fibromyalgia, by electrical stimulation of a nerve. The method comprises applying a first stimulus to a patient having a medical condition and measuring a first baseline physiological response from the patient. An electrical impulse is applied to a nerve within the patient and second stimulus is applied to the patient. A second physiological response evoked by the second stimulus is measured and compared to the first baseline physiological response. The methods may be used to optimize the placement of a stimulator, to test whether a patient is a suitable candidate for treatment using nerve stimulation, and/or to select the stimulation parameters that optimize acute or chronic treatment.
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公开(公告)号：US20240216682A1
公开(公告)日：2024-07-04
申请号：US18396958
申请日：2023-12-27
申请人： ElectroCore, Inc.
发明人： Jeckin Shah , Tanja Martin , Mike Romaniw , Muhammad Basit Qari
CPC分类号： A61N1/36031 , A61N1/0456 , A61N1/0496 , A61N1/36034
摘要： Systems, devices and methods are provided for delivering energy impulses (and/or fields) to bodily tissues for therapeutic purposes. A system for stimulating a nerve within a patient comprises a stimulator having an electrode configured for contacting the outer skin surface at, or near the target location and an energy source coupled to the stimulator, The energy source is configured to generate at least one electrical impulse and to transmit the electrical impulse transcutaneously from the electrode through the outer skin surface of the patient to a selected nerve in the patient adjacent to, or near, the target location. The system further comprises a software application configured for downloading onto a user interface. The software application controls parameters of the stimulator, which may be based on a physiological parameter of the patient and/or user status information related to the effectiveness of the therapy.
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公开(公告)号：US11839764B2
公开(公告)日：2023-12-12
申请号：US17346266
申请日：2021-06-13
申请人： ELECTROCORE, INC
发明人： Joseph P. Errico , Steven Mendez , Bruce J. Simon
CPC分类号： A61N1/36021 , A61N1/0456 , A61N1/3603 , A61N1/36025 , A61N1/36034 , A61N1/3756 , A61N1/3787 , A61N1/37217 , H04M1/21 , A61B5/0071 , A61B5/066 , A61B5/6898 , A61B5/7425 , H04M2250/12
摘要： Systems and methods are disclosed that allow a patient to self-treat a medical condition, such as migraine headache and trigeminal neuralgia and the like, by noninvasive electrical stimulation of nerves of the head, particularly supraorbital, supratrochlear, infraorbital, and mental nerves in the vicinity of their foramen or notch. The system comprises a stimulator having one or more electrodes that apply electrical impulses transcutaneously through the patient's skin to the targeted nerve. The stimulator may be coupled to a handheld mobile device, such as a smartphone, for receiving a treatment regimen to treat the medical condition. The system is designed to address problems that arise particularly during self-treatment, when a medical professional is not present.
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公开(公告)号：US20230277838A1
公开(公告)日：2023-09-07
申请号：US18092392
申请日：2023-01-02
申请人： ELECTROCORE, INC
发明人： J. P. Errico , Bruce J. Simon , Peter Staats
CPC分类号： A61N1/0456 , A61N1/0492 , A61N1/36007 , A61N1/36021 , A61N1/36034
摘要： Devices, systems and methods are provided for symptoms in patients, such as postoperative symptoms following major surgery and/or for treating patients in critical or intensive care. A device includes a patch having an adhesive surface for adhering to an outer skin surface of the patient and comprising one or more electrodes. An energy source is wirelessly coupled to the electrodes and configured to generate at least one electrical impulse and to wirelessly transmit the at least one electrical impulse transcutaneously from the electrodes through the outer skin surface of the patient to a selected nerve in the patient according to a stimulation protocol. The stimulation protocol includes administering at least one dose of about sixty seconds to about 5 minutes each day for a plurality of days. The doses may be administered before and after the patient’s surgery, or while the patient is being treating in intensive care.
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公开(公告)号：US20230201569A1
公开(公告)日：2023-06-29
申请号：US18117542
申请日：2023-03-06
申请人： ELECTROCORE, INC.
发明人： Bruce J. Simon , Joseph P. Errico , John T. Raffle
CPC分类号： A61N1/0456 , H04R25/505 , H04R25/305 , H04R25/70 , A61N1/36021 , A61N1/40 , A61N2/008 , A61N2/02 , A61N1/36034 , A61N1/36014 , A61N1/36053 , A61N1/36075 , A61N2/006
摘要： Vagal nerve stimulation devices and methods are provided for treating medical conditions, such as conditions associated with insufficient dopamine and/or endogenous opioids in the brain. A device includes one or more electrodes having a contact surface for contacting an outer skin surface of a patient and an energy source coupled to the electrodes. The energy source generates one or more electrical impulses and transmits the electrical impulses to the electrodes and transcutaneously through the outer skin surface of the patient at or near a vagus nerve. The one or more electrical impulses is sufficient to modulate the vagus nerve and release dopamine and/or endogenous opioids in a brain of the patient.
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公开(公告)号：US11684778B2
公开(公告)日：2023-06-27
申请号：US17002347
申请日：2020-08-25
申请人： ElectroCore, Inc.
IPC分类号： A61N1/36 , G16H40/63 , G16H10/65 , G16H40/40 , G16H20/10 , A61N1/02 , G06K7/14 , G06K7/10 , A61N1/04 , G16H20/30
CPC分类号： A61N1/36034 , A61N1/025 , A61N1/0456 , G06K7/10366 , G06K7/1413 , G06K7/1417 , G16H10/65 , G16H20/10 , G16H20/30 , G16H40/40 , G16H40/63
摘要： A system includes a medical device comprising a reader and a processor, and a storage medium containing a content. The reader is configured to read the content from the storage medium such that the processor switches the medical device from a first mode to a second mode based on the content. The processor or the reader is configured to interface with the storage medium based on the processor switching the medical device from the first mode to the second mode such that the content of the storage medium is deleted or scrambled. Once the content in the storage medium is erased or scrambled, it is no longer usable by the medical device until additional content has been loaded or programmed into the storage medium.
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公开(公告)号：US20230154605A1
公开(公告)日：2023-05-18
申请号：US18099159
申请日：2023-01-19
申请人： ELECTROCORE, INC
CPC分类号： G16H40/63 , G06Q20/202 , G16H50/20 , G16H20/13 , G06Q20/20 , G06K7/1417
摘要： A medical device, such as a neurostimulator, is provided that includes a housing, a power supply, a signal generator and one or more electrodes coupled to the housing. The signal generator is configured to apply one or more electrical impulses to the one or more electrodes for a period of time, the period of time being defined as a single dose. A memory is coupled to the housing and stores a first content corresponding to a time period that has elapsed and a second content corresponding to a number of single doses that have been emitted by the signal generator. The device is configured to switch from an activated mode and a deactivated mode upon a first occurrence of either a specific number of single doses have been emitted by the signal generator or a specific time period has elapsed.
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公开(公告)号：US20230113505A1
公开(公告)日：2023-04-13
申请号：US18079853
申请日：2022-12-12
申请人： ELECTROCORE, INC
发明人： Bruce J. Simon , Joseph P. Errico , John T. Raffle
摘要： Methods and devices are disclosed for the non-invasive treatment of autoimmune diseases or disorders through the delivery of energy to target nervous tissue, particularly the vagus nerve.. A device for treating an autoimmune disease or disorder comprises one or more electrodes having a contact surface configured for contacting an anterior portion of an outer skin surface of a neck of a patient and an energy source coupled to the electrodes. The energy source is configured to generate one or more electrical impulses and to transmit the electrical impulses to the electrodes and transcutaneously through the anterior portion of the outer skin surface of the neck of the patient at or near a vagus nerve. The electrical impulses are sufficient to modulate the vagus nerve and to inhibit inflammation and treat the disorder.
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公开(公告)号：US11581090B2
公开(公告)日：2023-02-14
申请号：US16229299
申请日：2018-12-21
申请人： ElectroCore, Inc.
摘要： A system includes: a processor; a memory coupled to the processor, wherein the memory stores a first content; a medical device coupled to the processor; and a reader coupled to the processor, wherein the reader is configured to read a second content from a storage medium other than the memory such that the processor switches the medical device from a first mode to a second mode based on the first content corresponding to the second content.
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公开(公告)号：US20220378359A1
公开(公告)日：2022-12-01
申请号：US17874364
申请日：2022-07-27
申请人： ELECTROCORE, INC
发明人： Bruce J. Simon , Joseph P. Errico
摘要： Systems and methods for remote therapy and patient monitoring are provided. A method comprises contacting an outer skin surface of a patient with a contact surface of a stimulator and transmitting an electrical impulse from the stimulator transcutaneously through the outer skin surface to a nerve within the patient. Data related to parameters of the electrical impulse applied to the nerve is stored and transmitted to a remote source. The data may include duration of treatment, amplitude of the electrical impulse, compliance with a prescribed therapy regimen or other relevant data related to the therapy. The method may further include collecting patient status data, such as symptoms of a medical condition (e.g., severity of a headache) before, during and/or after stimulation. The patient status data is correlated with the treatment data to monitor compliance and/or the effectiveness of the therapy.
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