发明授权
- 专利标题: Azetidinyl diamides as monoacylglycerol lipase inhibitors
- 专利标题(中): 氮杂环丁烷二酰胺作为单酰基甘油脂肪酶抑制剂
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申请号: US13867372申请日: 2013-04-22
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公开(公告)号: US08962607B2公开(公告)日: 2015-02-24
- 发明人: Haiyan Bian , Kristen Chevalier , Jose Clemente , Peter J Connolly , Christopher Flores , Shu-Chen Lin , Li Liu , John Mabus , Mark Macielag , Mark M McDonnell , Philip M Pitis , Yue-Mei Zhang , Sui-Po Zhang , Bin Zhu
- 申请人: Janssen Pharmaceutica NV
- 申请人地址: BE Beerse
- 专利权人: Janssen Pharmaceutica NV
- 当前专利权人: Janssen Pharmaceutica NV
- 当前专利权人地址: BE Beerse
- 代理商 Thomas J. Dodd
- 主分类号: A61K31/496
- IPC分类号: A61K31/496 ; A61K31/55 ; A61K31/5377 ; A61K31/519 ; A61K31/506 ; A61K31/541 ; C07D405/12 ; C07D417/14 ; C07D409/14 ; C07D411/14 ; C07D471/04 ; C07D495/04 ; C07D491/048 ; C07D413/14 ; C07D403/10 ; C07D205/04 ; C07D401/10 ; C07D401/12 ; C07D403/12 ; C07D403/14 ; C07D417/12 ; C07D409/06 ; C07D417/06 ; C07D403/06 ; C07D409/12 ; C07D401/14 ; C07D403/04
摘要:
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, Z, R1, and s are defined herein.
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