Invention Grant
- Patent Title: Optimized FC variants
- Patent Title (中): 优化的FC变体
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Application No.: US13257502Application Date: 2010-03-19
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Publication No.: US08742074B2Publication Date: 2014-06-03
- Inventor: Christian Behrens , Sylvie Jorieux , Abdelhakim Kharrat , Khalil Bouayadi , Philippe Mondon , Celine Monnet-Mars
- Applicant: Christian Behrens , Sylvie Jorieux , Abdelhakim Kharrat , Khalil Bouayadi , Philippe Mondon , Celine Monnet-Mars
- Applicant Address: FR Les Ulis
- Assignee: Laboratoire Francais du Fractionnement et des Biotechnologies
- Current Assignee: Laboratoire Francais du Fractionnement et des Biotechnologies
- Current Assignee Address: FR Les Ulis
- Agency: Foley & Lardner LLP
- Priority: EP09305250 20090320
- International Application: PCT/EP2010/053644 WO 20100319
- International Announcement: WO2010/106180 WO 20100923
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07H21/04 ; C12N15/00 ; C12N5/00 ; C12N1/20 ; C12P21/04
Abstract:
A variant of a parent polypeptide including an Fc region, which variant exhibits increased binding to FcRn as compared to the parent polypeptide and includes at least one amino acid modification in the Fc region.
Public/Granted literature
- US20120009188A1 OPTIMIZED FC VARIANTS Public/Granted day:2012-01-12
Information query
