- 专利标题: Expression of human milk proteins in transgenic plants
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申请号: US10639835申请日: 2003-08-12
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公开(公告)号: US07417178B2公开(公告)日: 2008-08-26
- 发明人: Ning Huang , Raymond L. Rodriguez , Frank E. Hagie
- 申请人: Ning Huang , Raymond L. Rodriguez , Frank E. Hagie
- 申请人地址: US CA Sacramento
- 专利权人: Ventria Bioscience
- 当前专利权人: Ventria Bioscience
- 当前专利权人地址: US CA Sacramento
- 代理机构: Perkins Coie LLP
- 代理商 Susan J. Myers Fitch; Peter J. Denlinger
- 主分类号: C12N15/82
- IPC分类号: C12N15/82 ; A01H5/00 ; C07H21/04
摘要:
The invention is directed to seed and seed extract compositions containing levels of a human milk protein between 3-40% or higher of the total protein weight of the soluble protein extractable from the seed. Also disclosed is a method of producing the seed with high levels of extractable human milk protein. The method includes transforming a monocotyledonous plant with a chimeric gene having a protein-coding sequence encoding a protein normally present in human milk under the control of a seed maturation-specific promoter. The method may further includes a leader DNA sequence encoding a monocot seed-specific transit sequence capable to target a linked milk protein to a storage body.
公开/授权文献
- US20040111766A1 Expression of human milk proteins in transgenic plants 公开/授权日:2004-06-10
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