Invention Grant
- Patent Title: Polypeptide conjugates with extended circulating half-lives
- Patent Title (中): 具有延长的循环半衰期的多肽缀合物
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Application No.: US10487025Application Date: 2002-08-09
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Publication No.: US07186797B2Publication Date: 2007-03-06
- Inventor: Theodore R. West , Thomas J McMurry , Stephane Dumas , Andrew Kolodziej
- Applicant: Theodore R. West , Thomas J McMurry , Stephane Dumas , Andrew Kolodziej
- Applicant Address: US MA Lexington
- Assignee: Epix Pharmaceuticals, Inc.
- Current Assignee: Epix Pharmaceuticals, Inc.
- Current Assignee Address: US MA Lexington
- Agency: Fish & Richardson P.C.
- International Application: PCT/US02/25323 WO 20020809
- International Announcement: WO03/013573 WO 20030220
- Main IPC: C07K1/113
- IPC: C07K1/113 ; C07K2/00 ; C07K14/435
Abstract:
The present invention relates to compounds and methods for synthesizing compounds wherein the compounds exhibit extended circulating half-life in the blood. The increase in circulating half-life is achieved by conjugating polypeptides to binding groups that exhibit high affinity for human serum albumin.
Public/Granted literature
- US20040254119A1 Polypeptide conjugates with extended circulating half-lives Public/Granted day:2004-12-16
Information query
