发明授权
- 专利标题: 6,7-oxygenated steroids and uses related thereto
- 专利标题(中): 6,7-氧合类固醇及其相关用途
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申请号: US893575申请日: 1997-07-10
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公开(公告)号: US6046185A公开(公告)日: 2000-04-04
- 发明人: David L. Burgoyne , Yaping Shen , John M. Langlands , Christine Rogers , Joseph H.-L. Chau , Edward Piers , Hassan Salari
- 申请人: David L. Burgoyne , Yaping Shen , John M. Langlands , Christine Rogers , Joseph H.-L. Chau , Edward Piers , Hassan Salari
- 申请人地址: CAX Richmond CAX Vancouver CAX Alberta
- 专利权人: Inflazyme Pharmaceuticals Ltd.,The University of British Columbia,The University of Alberta
- 当前专利权人: Inflazyme Pharmaceuticals Ltd.,The University of British Columbia,The University of Alberta
- 当前专利权人地址: CAX Richmond CAX Vancouver CAX Alberta
- 主分类号: A61K31/56
- IPC分类号: A61K31/56 ; C07J1/00 ; C07J3/00 ; C07J7/00 ; C07J9/00 ; C07J13/00 ; C07J17/00 ; C07J21/00 ; C07J31/00 ; C07J41/00 ; C07J51/00 ; C07J71/00
摘要:
Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have oxygen substitution at C6 and C7, and some have specific stereochemistries such as 6.alpha. and 7.beta. oxygen substitution, and an alpha hydrogen at the 5 position in addition to having 6.alpha. and 7.beta. oxygen substitution. Steroids having 3,4-epoxy functionality are also disclosed. In addition, steroids having C17 pyran and .delta.-lactone functionality, with oxygen substitution at C6 and C7, or at C15, of the steroid nucleus, are disclosed.
公开/授权文献
- US4204829A Catalytic combustion process and system 公开/授权日:1980-05-27
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