发明授权
- 专利标题： Aminopyridine compounds
- 专利标题（中）： 氨基吡啶化合物
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申请号： US53869申请日： 1993-04-29
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公开(公告)号： US5371086A公开(公告)日： 1994-12-06
- 发明人: Tadahiro Takemoto , Masahiro Eda , Mitsuyoshi Hihara , Takehiro Okada , Hiroshi Sakashita , Miyuki Eiraku , Chikara Fukaya , Norifumi Nakamura , Masanori Sugiura , Sumio Matzno , Maki Goda , Yasumi Uchida
- 申请人： Tadahiro Takemoto , Masahiro Eda , Mitsuyoshi Hihara , Takehiro Okada , Hiroshi Sakashita , Miyuki Eiraku , Chikara Fukaya , Norifumi Nakamura , Masanori Sugiura , Sumio Matzno , Maki Goda , Yasumi Uchida
- 申请人地址： JPX Osaka
- 专利权人： The Green Cross Corporation
- 当前专利权人： The Green Cross Corporation
- 当前专利权人地址： JPX Osaka
- 优先权： JPX3-76777 19910315
- 主分类号： C07D213/75
- IPC分类号： C07D213/75 ; C07D213/76 ; C07D213/77 ; C07D213/81 ; C07D213/84 ; C07D213/89 ; C07D405/12 ; C07D413/12 ; A61K31/495 ; A61K31/54 ; C07D211/56 ; C07D401/00
摘要：
An aminopyridine compound represented by the formula: ##STR1## wherein n represents 0 or 1; Z represents .dbd.S, .dbd.NCN or .dbd.CHNO.sub.2 ; R.sub.1 represents --NR.sub.3 R.sub.4, --NHNR.sub.3 R.sub.4, --NHCONHR.sub.3 or --NHSO.sub.2 R.sub.3 ; R.sub.2 represents H, or substituted or unsubstituted alkyl; R.sub.3 and R.sub.4, which may be the same or different, represent H, substituted or unsubstituted alkyl, aryl, substituted or unsubstituted acyl or alkoxycarbonyl group; and R.sub.3 and R.sub.4 may form a heterocyclic ring together with a nitrogen atom to which R.sub.3 and R.sub.4 are bound, through another heteroatom or without it; an optical isomer thereof or art acid salt thereof, which is excellent in pharmacological effect and repressed in side effects as a drug for circulatory diseases.
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