Invention Application
- Patent Title: FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE
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Application No.: US15899021Application Date: 2018-02-19
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Publication No.: US20180238912A1Publication Date: 2018-08-23
- Inventor: Jeffrey DZUBAY , Kyle Gee , Vladimir Martin , Aleksey Rukavishnikov , Daniel Beacham
- Applicant: LIFE TECHNOLOGIES CORPORATION
- Main IPC: G01N33/84
- IPC: G01N33/84 ; C09B11/24 ; C07K1/13 ; C09B7/00 ; C09B11/12 ; C09B11/28 ; C09B57/00 ; G01N31/22 ; G01N33/50 ; G01N33/58 ; C09K11/06 ; C07D311/82 ; C07D311/90 ; C07D405/12 ; C07D413/04 ; C07D491/22 ; C07D209/14 ; C07F5/02 ; C09B69/00 ; G01N33/80
Abstract:
A new class of pH sensitive fluorescent dyes and assays relating thereto are described. The dyes and assays are particularly suited for biological applications including phagocytosis and monitoring intracellular processes. The pH sensitive fluorescent dyes of the present invention include compounds of Formula I: wherein the variables are described throughout the application.
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