Invention Application
US20120172402A1 INDUCTION OF ALPHA HELIX CONFORMATIONS IN PROTEINS AND PEPTIDES
有权
诱导蛋白质和蛋白质中的ALPHA HELIX一致性
- Patent Title: INDUCTION OF ALPHA HELIX CONFORMATIONS IN PROTEINS AND PEPTIDES
- Patent Title (中): 诱导蛋白质和蛋白质中的ALPHA HELIX一致性
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Application No.: US13383266Application Date: 2010-07-09
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Publication No.: US20120172402A1Publication Date: 2012-07-05
- Inventor: Hans-Günther Schmalz , Ronald Kuhne , Verena Hack , Cédric Reuter
- Applicant: Hans-Günther Schmalz , Ronald Kuhne , Verena Hack , Cédric Reuter
- Applicant Address: DE Berlin DE Koln
- Assignee: FORSCHUNGSVERBUND BERLIN E.V.,UNIVERSITAT ZU KOLN
- Current Assignee: FORSCHUNGSVERBUND BERLIN E.V.,UNIVERSITAT ZU KOLN
- Current Assignee Address: DE Berlin DE Koln
- Priority: DE102009032902.1 20090710
- International Application: PCT/EP2010/004213 WO 20100709
- Main IPC: A61K31/429
- IPC: A61K31/429 ; C07K1/107 ; C40B50/00 ; C40B40/10 ; C07D498/18 ; C07D487/18 ; A61K31/424 ; A61K31/407 ; A61P35/00 ; A61P25/28 ; A61P31/12 ; A61P31/04 ; C07K2/00 ; C07K14/00 ; C07D513/18
Abstract:
Substituted tricyclic diproline analogues of the formula (I): wherein the variables are as defined herein. Also disclosed are methods for the production thereof, the use thereof for the induction of an alpha-helix conformation in peptides and/or proteins, pharmaceuticals containing said compounds, methods for the production of a peptide library containing said compounds, and peptide libraries containing said compounds.
Public/Granted literature
- US08815932B2 Induction of alpha helix conformations in proteins and peptides Public/Granted day:2014-08-26
Information query
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