Invention Application
- Patent Title: OLIGOSACCHARIDE MODIFICATION AND LABELING OF PROTEINS
- Patent Title (中): 蛋白质的寡糖修饰和标记
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Application No.: US13007506Application Date: 2011-01-14
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Publication No.: US20110207171A1Publication Date: 2011-08-25
- Inventor: Brian Agnew , Schuyler B. CORRY , Kyle R. GEE
- Applicant: Brian Agnew , Schuyler B. CORRY , Kyle R. GEE
- Applicant Address: US CA Carlsbad
- Assignee: LIFE TECHNOLOGIES CORPORATION
- Current Assignee: LIFE TECHNOLOGIES CORPORATION
- Current Assignee Address: US CA Carlsbad
- Main IPC: C12P33/00
- IPC: C12P33/00 ; C12P21/00 ; C07K16/00 ; C12N9/96
Abstract:
The present invention generally relates to methods of functionalizing proteins, particularly antibodies, at oligosaccharide linkages, methods of humanizing antibodies by modifying glycosylation, as well as to novel antibodies linked to modified oligosaccharides. The invention further relates to kits that may be used to produce the antibodies of the invention.
Public/Granted literature
- US08785212B2 Oligosaccharide modification and labeling of proteins Public/Granted day:2014-07-22
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