Invention Application
- Patent Title: The Use of Novel Coumarins as Glutathione and Thiol Labels
- Patent Title (中): 使用新型香豆素作为谷胱甘肽和硫醇标签
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Application No.: US12666256Application Date: 2008-07-24
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Publication No.: US20110045503A1Publication Date: 2011-02-24
- Inventor: Kyle Gee , Michael Janes , Iain Johnson , Hee Chol Kang
- Applicant: Kyle Gee , Michael Janes , Iain Johnson , Hee Chol Kang
- Applicant Address: US CA Carlsbad
- Assignee: LIFE TECHNOLOGIES CORPORATION
- Current Assignee: LIFE TECHNOLOGIES CORPORATION
- Current Assignee Address: US CA Carlsbad
- International Application: PCT/US2008/071085 WO 20080724
- Main IPC: G01N33/52
- IPC: G01N33/52 ; C07D471/06

Abstract:
Fluorescent quinolizinocoumarin compounds substituted with electrophilic reactive groups that bind thiol compounds are described. The compounds are useful in detecting oxidative stress and processes associated therewith in live cells.
Public/Granted literature
- US08981100B2 Use of novel coumarins as glutathione and thiol labels Public/Granted day:2015-03-17
Information query
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