- 专利标题： Synthetic single domain antibody
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申请号： US17190626申请日： 2021-03-03
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公开(公告)号： US11866484B2公开(公告)日： 2024-01-09
- 发明人: Aurelien Olichon , Sandrine Moutel , Franck Perez
- 申请人： INSERM (Institut National de la Sante et de la Recherche Medicale) , Institut Curie , Universite Paul Sabatier Toulouse III , Centre National de la Recherche Scientifique (CNRS)
- 申请人地址： FR Paris
- 专利权人： INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE),INSTITUT CURIE,UNIVERSITE PAUL SABATIER TOULOUSE III,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
- 当前专利权人： INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE),INSTITUT CURIE,UNIVERSITE PAUL SABATIER TOULOUSE III,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
- 当前专利权人地址： FR Paris; FR Paris; FR Toulouse; FR Paris
- 代理机构： WC&F IP
- 优先权： EP 191444 2013.11.04
- 主分类号： C40B50/06
- IPC分类号： C40B50/06 ; C07K16/00 ; C07K16/32 ; C07K16/44 ; C40B40/08 ; C07K16/40 ; C40B40/10
摘要：
The invention relates to the identification of a highly stable single domain antibody scaffold (hs2dAb) and its use in generating synthetic single domain antibody library (hs2dAb-L1). The invention also relates to antigen-binding proteins comprising said stable single domain antibody scaffold and their uses, in particular as therapeutics.
公开/授权文献
- US20210347855A1 Synthetic Single Domain Antibody 公开/授权日：2021-11-11
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