Provided is an electrostatic discharge protection circuit, including a first resistor, a first transistor, a second resistor, and a second transistor. The first resistor has a first end coupled to a first power rail. The first transistor has a first end coupled to the first power rail, and a control end of the first transistor is coupled to a second end of the first resistor. The second resistor is coupled between a second end of the first transistor and a second power rail. The second transistor has a first end coupled to the first power rail, a control end of the second transistor is coupled to the second end of the first transistor, and a second end of the second transistor is coupled to the second power rail.