- 专利标题： Engineered purine nucleoside phosphorylase variant enzymes
-
申请号： US16460025申请日： 2019-07-02
-
公开(公告)号： US11162105B2公开(公告)日： 2021-11-02
- 发明人: Scott J. Novick , Nikki Dellas , Vesna Mitchell , Da Duan , Jovana Nazor , Oscar Alvizo , Auric Anthony Sowell-Kantz , Jeffrey C. Moore , Mark Huffman , Agustina Rodriguez-Granillo , Deeptak Verma , Nicholas M. Marshall , Jay Russell , Keith A. Canada
- 申请人： Codexis, Inc.
- 申请人地址： US CA Redwood City
- 专利权人： Codexis, Inc.
- 当前专利权人： Codexis, Inc.
- 当前专利权人地址： US CA Redwood City
- 代理机构： Codexis, Inc.
- 主分类号： C12N15/63
- IPC分类号： C12N15/63
摘要：
The present invention provides engineered purine nucleoside phosphorylase (PNP) enzymes, polypeptides having PNP activity, and polynucleotides encoding these enzymes, as well as vectors and host cells comprising these polynucleotides and polypeptides. Methods for producing PNP enzymes are also provided. The present invention further provides compositions comprising the PNP enzymes and methods of using the engineered PNP enzymes. The present invention finds particular use in the production of pharmaceutical compounds.
公开/授权文献
信息查询
IPC分类:
