A home therapy entry, modification and reporting system includes a website configured to display therapy entry, modification and reporting information and a system hub configured to manage a flow of the information between the website and a plurality of home therapy machines. The website specifically includes a therapy prescription screen configured to specify supplies needed at the patient's home or dwelling for operation with one of the home therapy machines, a device program screen configured to set parameters by which at least one of the home therapy machines operates to perform the home therapy on the patient, and a clinician dashboard screen including a list of patients and a notification associated with at least one of the listed patients, the notification indicating whether a predefined treatment condition or alert occurred during the home therapy.