The invention discloses an axle box end cover positioning and centering mechanism for a gauge-changeable bogie. The axle box end cover positioning and centering mechanism for the gauge-changeable bogie comprises a positioning and centering end cover mounting seat, a positioning and centering end cover and a centering roller assembly; four end cover U-shaped grooves are formed in the axle box end cover positioning and centering mechanism for the gauge-changeable bogie; the positioning and centering end cover mounting seat is connected with a locking sleeve bolt of a wheel pair locking mechanismthrough a positioning and centering end cover mounting seat mounting hole; a positioning and centering end cover mounting threaded hole mounted together with the positioning and centering end cover is formed in the positioning and centering end cover mounting seat; the centering roller assembly is mounted on the positioning and centering end cover; and the centering roller assembly rolls on an assorted gauge-changeable driving rail. The axle box end cover positioning and centering mechanism for the gauge-changeable bogie is used for transverse positioning and centering in the gauge changing process and applicable to an end surface driving type gauge-changeable bogie gauge changing device.