The invention discloses a high-precision assembly process for multi-point compression-type large-scale equipment. The high-precision assembly process comprises the following steps: separation; primarymeasurement; transferring; secondary measurement; position and posture adjustment; and assembly. Through the precise cooperation between auxiliary measuring tools and compression seats, the positionsand postures of all compression points can be measured by using a laser tracker; through the comparison and analysis of two sets of data, the position degree coordination data of all the compressionpoints can be finally acquired as well as the position and posture adjustment degrees of all the compression seats can be provided; through the position and posture adjustment degrees, all the compression seats can be adjusted in pact at a time; and accordingly, the multi-point compression-type large-scale equipment can be loaded in place at a time under the premise that the loading precision requirement is met. By adoption of the high-precision assembly process disclosed by the invention, the multi-point compression-type large-scale equipment can be loaded in place at a time under the premisethat the mounting precision is guaranteed, and the requirements for reducing the operation complexity and the operation risk as well as improving the loading efficiency can be met.