The invention relates to a driving fatigue judgment method based on a driver electrocardiogram RR interval. The method comprises the steps of acquiring a driver electrocardiosignal and extracting an electrocardiogram RR interval; according to a stationary model based on the electrocardiogram RR interval, calculating a corresponding sequence structure residual error; according to a first-order autocorrelation model, calculating autoregression residual errors of an autoregression residual error sequence corresponding to all moments; according to a GARCH (1,1) model of a condition variance, calculating condition variances of a condition variance sequence corresponding to all the moments; according to the condition variance corresponding to the current moment, judging whether a fatigue grade of a driver changes or not. According to the driving fatigue judgment method based on the driver electrocardiogram RR interval, the problem in the prior art is solved that fatigue driving judgment subjectivity is too high and judgment standards are different due to individual difference, and the method has high objectivity and general applicability.