The invention discloses an adjustment locking mechanism for spatial attitude of a suspended type large-scale member, comprising a portal type steel frame and a servo car arranged in the horizontal plane. Lifting motors are arranged on a cross beam of the portal type steel frame, the lifting motors are connected with suspension points on the member through arranged tightwires and lift the upper part of the member, the servo car is connected with a supporting point on the member and supports the lower part of the member, and the spatial attitude of the member is adjusted by adjusting the length extended by the tightwires. The member is provided with a limit point, a limit mechanism for limiting lateral displacement of the limit point is arranged between the limit point and the portal type steel frame, and/or a positioning mechanism is arranged between the servo car and the horizontal plane. The invention has the advantages of simple design, low cost, easy implementation and high reliability; and the attitude positioning requirements of the member can be greatly improved by arranging the limit mechanism and/or the positioning mechanism so as to improve the attitude measuring accuracy of the member.