公开(公告)号：US4614823A

公开(公告)日：1986-09-30

申请号：US607832

申请日：1984-07-11

申请人： Curtis L. Kirkemo ,  Mohammed T. Shipchandler

发明人： Curtis L. Kirkemo ,  Mohammed T. Shipchandler

IPC分类号： C07D493/10 ,  C07J41/00 ,  G01N33/74 ,  C07D239/62 ,  C07D473/08 ,  C07D493/12

CPC分类号： C07D493/10 ,  C07J41/0016 ,  G01N33/74

摘要： This disclosure relates to a method and reagents for determining ligands in biological fluids such as serum, plasma, spinal fluid, amnionic fluid and urine. This disclosure also relates to a novel class of tracer compounds employed as reagents in fluorescence polarization immunoassays.

摘要翻译： 本公开涉及用于测定生物流体如血清，血浆，脊髓液，羊膜液和尿液中配体的方法和试剂。 本公开还涉及在荧光偏振免疫测定中用作试剂的新型示踪剂化合物。

公开(公告)号：US20180055778A1

公开(公告)日：2018-03-01

申请号：US15677286

申请日：2017-08-15

申请人： UPSHER-SMITH LABORATORIES, LLC

发明人： Sarah Michelle Betterman ,  Jaidev Srinivas Tantry ,  Laura Marie Patrick

IPC分类号： A61K9/50 ,  A61K31/7048 ,  A61K9/48 ,  A61K31/357 ,  A61K9/16 ,  C07D493/14 ,  A61K9/28 ,  C07D311/02 ,  C07D493/12

CPC分类号： A61K9/50 ,  A61K9/16 ,  A61K9/28 ,  A61K9/2866 ,  A61K9/4891 ,  A61K9/5047 ,  A61K31/357 ,  A61K31/7048 ,  C07D311/02 ,  C07D493/12 ,  C07D493/14 ,  Y10S514/963 ,  Y10S514/964

摘要： An extended-release topiramate capsule that includes a capsule shell containing a single population of coated particles; wherein each coated particle includes a core and a coating thereon; wherein each particle core includes a homogeneous mixture comprising topiramate throughout its core; and wherein the coating includes one or more release controlling agent(s).

公开(公告)号：US20080207747A1

公开(公告)日：2008-08-28

申请号：US11631506

申请日：2005-07-05

申请人： Masaaki Nakai ,  Yuko Fukui ,  Sumio Asami ,  Fumio Hashimoto

发明人： Masaaki Nakai ,  Yuko Fukui ,  Sumio Asami ,  Fumio Hashimoto

IPC分类号： C07D311/04 ,  C07D493/12 ,  A61K31/365 ,  A61K31/352 ,  A61P3/06

CPC分类号： A61K36/82 ,  A23F3/163 ,  A23L2/52 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/352 ,  A61K31/353 ,  C07D311/62 ,  C07D493/14 ,  A23V2250/21 ,  A23V2250/214 ,  A23V2200/332 ,  A23V2200/326

摘要： The present invention provides lipase inhibitors containing flavan-3-ol monomers or acylates thereof derived from teas as well as foods and beverages and medicines containing said inhibitors. More specifically, the present invention provides lipase inhibitors containing at least one of flavan-3-ol monomers represented by the formula: wherein R1 and R3 independently represent H or OH, R2 represents H, R4 represents H, G, 3MeG or p-cou, R5 represents H or G, R4′ and R5′ independently represent H or G, R4″ represents H or G, and G, 3MeG and p-cou respectively represent the groups of the formulae: or acylates thereof; as well as foods and beverages and medicines containing said lipase inhibitors.

摘要翻译： 本发明提供了含有衍生自茶的黄烷-3-醇单体或其酰化物以及含有所述抑制剂的食品和饮料以及药物的脂肪酶抑制剂。 更具体地，本发明提供了含有下式所示的黄烷-3-醇单体中的至少一种的脂肪酶抑制剂：其中R 1和R 3独立地表示H或OH R 2代表H，R 4代表H，G，3MeG或对 - 可可，R 5代表H或G，R _{4 <＆gt;和R 5'独立地表示H或G，R 4'表示H或G，并且G，3MeG和p-cou分别表示 下式的基团：或其酰化物; 以及含有所述脂肪酶抑制剂的食品和饮料和药物。}

公开(公告)号：US20040072252A1

公开(公告)日：2004-04-15

申请号：US10679368

申请日：2003-10-07

发明人： Brooks Edwards ,  Irena Bronstein ,  Zhixian Wang

IPC分类号： G01N033/53 ,  C07D417/14 ,  C07D493/12

CPC分类号： C07D417/04 ,  C07D277/62 ,  C07D493/04 ,  C07F9/65512 ,  C07F9/65586 ,  C09K9/02 ,  G01N33/582

摘要： Chemiluminescent heteroaryl substituted benzothiazole 1,2-dioxetane compounds capable of producing light energy when decomposed are provided. These chemiluminescent compounds are represented by the general formula: 1 The heteroaryl substituent Y can be, for example, a pyridyl group or a benzothiazolyl group. The heteroaryl substituted benzothiazole compounds are substantially stable at room temperature. Kits including the heteroaryl substituted dioxetane compounds as well as methods for using these compounds for detecting the presence of one or more analytes in a sample are also provided.

摘要翻译： 提供了能够在分解时产生光能的化学发光的杂芳基取代的苯并噻唑1,2-二氧杂环丁烷化合物。 这些化学发光化合物由通式表示：杂芳基取代基Y可以是例如吡啶基或苯并噻唑基。 杂芳基取代的苯并噻唑化合物在室温下基本稳定。 还提供了包括杂芳基取代的二恶丁环化合物的试剂盒以及使用这些化合物检测样品中一种或多种分析物的存在的方法。

公开(公告)号：US4143139A

公开(公告)日：1979-03-06

申请号：US819471

申请日：1977-07-27

申请人： Jasjit S. Bindra

发明人： Jasjit S. Bindra

IPC分类号： A61K31/325 ,  A61K31/35 ,  A61K31/352 ,  A61K31/353 ,  A61K31/44 ,  A61K31/443 ,  A61K31/445 ,  A61K31/495 ,  A61K31/535 ,  A61P1/04 ,  A61P9/12 ,  A61P25/04 ,  A61P25/20 ,  A61P29/00 ,  A61P37/06 ,  C07C37/055 ,  C07C39/15 ,  C07C43/205 ,  C07C45/00 ,  C07D213/30 ,  C07D303/22 ,  C07D311/16 ,  C07D311/18 ,  C07D311/20 ,  C07D311/22 ,  C07D311/74 ,  C07D311/80 ,  C07D311/92 ,  C07D405/06 ,  C07D493/12

CPC分类号： C07D213/30 ,  C07C37/055 ,  C07C43/2055 ,  C07C45/00 ,  C07C45/004 ,  C07D303/22 ,  C07D311/16 ,  C07D311/18 ,  C07D311/20 ,  C07D311/22 ,  C07D311/80

摘要： 9-Hydroxydibenzo[b,d]pyrans useful as analgesics, hypotensives, immunosuppressants, tranquilizers; as anti-secretory and anti-anxiety drugs; intermediates therefor and derivatives thereof having the formulae ##STR1## wherein R is hydrogen or alkanoyl having from one to five carbon atoms; R.sub.1 is hydrogen, alkanoyl having from one to five carbon atoms or --CO--(CH.sub.2).sub.P --NR.sub.2 R.sub.3 wherein p is 0 or an integer from 1 to 4; each of R.sub.2 and R.sub.3 when taken individually is hydrogen or alkyl having from one to four carbon atoms; R.sub.2 and R.sub.3 when taken together with the nitrogen to which they are attached form a 5- or 6-membered heterocyclic ring selected from piperidino, pyrrolo, pyrrolidino, morpholino and N-alkylpiperazino having from one to four carbon atoms in the alkyl group;Each of R.sub.4 and R.sub.5 is hydrogen, methyl or ethyl;R.sub.0 is oxo or alkylenedioxy having from two to four carbon atoms;Z is(a) alkylene having from one to nine carbon atoms;(b) --(alk.sub.1).sub.m --X--(alk.sub.2).sub.n --wherein each of (alk.sub.1) and (alk.sub.2) has from 1 to 9 carbon atoms, with the proviso that the summation of carbon atoms in (alk.sub.1) plus (alk.sub.2) is not greater than 9;Each of m and n is 0 or 1;X is O, S, SO or SO.sub.2 ; andW is methyl, phenyl, p-chlorophenyl, p-fluorophenyl, pyridyl, piperidyl, cycloalkyl having from 3 to 7 carbon atoms, or monosubstituted cycloalkyl wherein the substituent is phenyl, p-chlorophenyl or p-fluorophenyl;With the proviso that when W is methyl, Z is--(alk.sub.1).sub.m --X---(alk.sub.2).sub.n --.

公开(公告)号：US20240262782A1

公开(公告)日：2024-08-08

申请号：US18404138

申请日：2024-01-04

申请人： ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD.

发明人： Jin-Man KIM ,  Seung-Hoon YOO ,  Hong-Se OH ,  Su-Hyun LEE ,  So-Mi PARK ,  Dong-Hyung LEE ,  Hyun-Woo KANG

IPC分类号： C07C211/54 ,  C07D209/88 ,  C07D307/91 ,  C07D333/76 ,  C07D493/12 ,  C09K11/06 ,  H10K85/60

CPC分类号： C07C211/54 ,  C07D209/88 ,  C07D307/91 ,  C07D333/76 ,  C07D493/12 ,  C09K11/06 ,  H10K85/622 ,  H10K85/626 ,  H10K85/633 ,  H10K85/636 ,  H10K85/654 ,  H10K85/6574 ,  H10K85/658 ,  C07C2603/40 ,  C09K2211/1014

摘要： The present disclosure relates to an organic electroluminescent compound and an organic electroluminescent device comprising the same. By comprising the organic electroluminescent compound according to the present disclosure as an organic electroluminescent material, an organic electroluminescent device having long lifespan characteristics can be provided.

公开(公告)号：US20110101319A1

公开(公告)日：2011-05-05

申请号：US12922635

申请日：2009-02-27

申请人： Takayuki Fukumatsu ,  Ikumi Ichihashi ,  Hiroshi Miyazaki ,  Atsushi Oda

发明人： Takayuki Fukumatsu ,  Ikumi Ichihashi ,  Hiroshi Miyazaki ,  Atsushi Oda

IPC分类号： H01L51/54 ,  C07D487/12 ,  C07D493/12

CPC分类号： H01L51/5088 ,  C07D487/04 ,  C07D493/14 ,  H01L51/005 ,  H01L51/0053 ,  H01L51/5048 ,  H01L2251/552

摘要： Provided are a hole-injecting material for an organic electroluminescent device (organic EL device) exhibiting high luminous efficiency at a low voltage and having greatly improved driving stability, and an organic EL device using the material. The hole-injecting material for an organic EL device is selected from benzenehexacarboxylic acid anhydrides, benzenehexacarboxylic acid imides, or N-substituted benzenehexacarboxylic acid imides. Further, the organic EL device has at least one light-emitting layer and at least one hole-injecting layer between an anode and a cathode arranged opposite to each other, and includes the above-mentioned hole-injecting material for an organic EL device in the hole-injecting layer. The organic EL device may contain a hole-transporting material having an ionization potential (IP) of 6.0 eV or less in the hole-injecting layer or a layer adjacent to the hole-injecting layer.

摘要翻译： 提供一种用于低电压且显着提高驱动稳定性的高发光效率的有机电致发光器件（有机EL器件）的空穴注入材料和使用该材料的有机EL器件。 用于有机EL器件的空穴注入材料选自苯六羧酸酐，苯六羧酸酰亚胺或N-取代苯六羧酸酰亚胺。 此外，有机EL器件具有至少一个发光层和在彼此相对布置的阳极和阴极之间的至少一个空穴注入层，并且包括上述用于有机EL器件的空穴注入材料 空穴注入层。 有机EL器件可以在空穴注入层或与空穴注入层相邻的层中含有电离电位（IP）为6.0eV以下的空穴传输材料。

公开(公告)号：US07521474B2

公开(公告)日：2009-04-21

申请号：US11494229

申请日：2006-07-27

申请人： Amy E. Wright ,  Shirley A. Pomponi ,  Peter J. McCarthy ,  Ying Chen ,  Ross E. Longley

发明人： Amy E. Wright ,  Shirley A. Pomponi ,  Peter J. McCarthy ,  Ying Chen ,  Ross E. Longley

IPC分类号： A61K31/335 ,  C07D325/04 ,  C07D493/12

CPC分类号： C07D493/18

摘要： The subject invention provides novel compositions of biologically active macrolide compounds which can advantageously be used in blocking cellular proliferation, treatment of cancer, treatment of fungal infections and control of spoilage of food, cosmetic and other consumer items.

摘要翻译： 本发明提供生物活性大环内酯化合物的新组合物，其可有利地用于阻断细胞增殖，治疗癌症，治疗真菌感染和控制食品，化妆品和其它消费品的腐败。

公开(公告)号：US07115756B2

公开(公告)日：2006-10-03

申请号：US10875670

申请日：2004-06-23

申请人： Amy E. Wright ,  Shirley A. Pomponi ,  Peter J. McCarthy ,  Ying Chen ,  Ross E. Longley

发明人： Amy E. Wright ,  Shirley A. Pomponi ,  Peter J. McCarthy ,  Ying Chen ,  Ross E. Longley

IPC分类号： C07D325/04 ,  C07D493/12

CPC分类号： C07D493/18

摘要： The subject invention provides novel compositions of biologically active macrolide compounds which can advantageously be used in blocking cellular proliferation, treatment of cancer, treatment of fungal infections and control of spoilage of food, cosmetic and other consumer items.

公开(公告)号：US4018795A

公开(公告)日：1977-04-19

申请号：US596110

申请日：1975-07-16

申请人： Earl Dan Flickinger ,  Charles Merlyn Buess

发明人： Earl Dan Flickinger ,  Charles Merlyn Buess

IPC分类号： C07D319/08 ,  C07D493/12

CPC分类号： C10M5/00

摘要： Compositions of matter having two ring nuclei composed of 6 carbon atoms essentially superimposed in fixed parallel planes with respect to each other and process of preparing the same. The compositions may be advantageously employed in lubricating grease.

摘要翻译： 具有由相对于彼此固定的平行平面重叠的6个碳原子构成的具有两个环核的物质组合物及其制备方法。 组合物可有利地用于润滑油脂中。