公开(公告)号：US3751413A

公开(公告)日：1973-08-07

申请号：US3751413D

申请日：1972-06-22

申请人： SCHRAVEN E ,  STACHEL A ,  NITZ R ,  STACHEL L ,  RESAG K ,  BEYERLE R

发明人： STACHEL A ,  SCHRAVEN E ,  NITZ R ,  RESAG K ,  STACHEL L ,  BEYERLE R

IPC分类号： C07D253/08 ,  C07D55/08

CPC分类号： C07D253/08 ,  Y10S514/929

摘要： THE PRESENT INVENTEION PERTAINS TO NEW, PHARMACOLOGICALLY VALUABLE BASICALLY SUBSTITUTED 1,2,3-BENZOTRIAZINE-4(3H)-ONE DERIVATIVES HAVING EXCELLENT CORONARY DILATOR PROPERTIES AND WHICH HAVE THE STRUCTURAL FORMULA

3-(((R3)M-PHENYL)-COO-CH(-CH2-R'')-CH2-),(R1)N-1,2,3-BENZO-

TRIAZIN-4(3H)-ONE

WHEREIN R'' IS A RADICAL SELECTED FROM THE GROUP CONSISTING OF N,N - DI - LOWER-ALKYLAMINO, N-LOWER-ALKYL-N-ALLYLAMINO, N-LOWER-ALKYL-N-(METHOXY-LOWER-ALKYL)-AMINO, N-LOWER-ALKYL-N-(DIETHYLAMINO-LOWER-ALKYL)-AMINO AND N-LOWER-ALKYL-N-BENZYL-AMINO,LOWER ALKYL MEANING ALKYL HAVING 1 TO 4 CARBON ATOMS, SAID RADICAL BEING BOUND VIA IS NITROGEN ATOM, R1 IS A LOIWER ALKOXY GROUP HAVING 1-4 CARBON ATOMS WHICH MAY BE IN THE 6,7 OR 6,7,8-POSITION, R2 IS AN ALKOXY GROUP HAVING 1-4 CARBON ATOMS, M IS AN INTEGER SELECTED FROM 1,2 AND 3, AND N IS AN INTEGER SELECTED FROM THE GROUP CONSISTING OF 2 AND 3 AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF.

公开(公告)号：US3471489A

公开(公告)日：1969-10-07

申请号：US3471489D

申请日：1968-07-29

申请人： DOW CHEMICAL CO

发明人： RIGTERINK RAYMOND H

IPC分类号： C07D253/08 ,  C07D55/08 ,  A01N9/22 ,  A61K27/00

CPC分类号： C07D253/08

公开(公告)号：US3479357A

公开(公告)日：1969-11-18

申请号：US3479357D

申请日：1967-10-20

申请人： SEARLE & CO

发明人： WAGNER HANS A

IPC分类号： C07D403/04 ,  C07D403/14 ,  C07D55/08 ,  C07D57/18

CPC分类号： C07D403/04 ,  C07D403/14 ,  Y10S514/925

公开(公告)号：US3420829A

公开(公告)日：1969-01-07

申请号：US3420829D

申请日：1966-05-12

申请人： BAYER AG

发明人： LORENZ WALTER

IPC分类号： A01N57/08 ,  C07F9/6521 ,  C07D55/08

CPC分类号： A01N57/08 ,  C07F9/65218

公开(公告)号：US3759907A

公开(公告)日：1973-09-18

申请号：US3759907D

申请日：1972-06-22

申请人： CASSELLA FARBWERKE MAINKUR AG

发明人： STACHEL A ,  NITZ R ,  RESAG K ,  STACHEL I ,  BEYERLE R ,  SCHRAVEN E

IPC分类号： C07D253/08 ,  C07D55/08

CPC分类号： C07D253/08 ,  Y10S514/929

摘要： THE PRESNET INVENTION PERTAINS TO NEW, PHARMACOLOGICALLY VALUABLE BASICALLY SUBSTITUTED 1,2,3-BENZOTHIAZINE4(3H)-ONE DERIVATIVES HAVING EXCELLENT CORONARY DILATOR PROERTIES AND WHICH HAVE THE STRUCTURAL FORMULA

3-((R2)M-C6H4-COO-CH(-CH2-R'')-CH2-),4-(O=),(R1)N-3,4-

DIHYDRO-1,2,3-BENZOTHIAZINE

WHEREIN R'' IS A N-METHYL-N-CYCLOALKYLAMINO RADICAL, CYCLOALKYL HAVING 3-6 CARBON ATOMS, SAID RADICAL BEING BOUND VIA ITS NITROGEN ATOM; R1 IS A LOWER ALKOXY GROUP HAVING 1-4 CARBON ATOMS WHICH MAY BE IN THE 6,7 OR 6,7,8-POSITION; R2 IS AN ALKOXY GROUP HAVING 1-4 CARBON ATOMS; M IS AN INTEGER SELECTED FROM 1, 2 AND 3; AND N IS AN INTEGER SELECTED FROM THE GROUP CONSISTING OF 2 AND 3 AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF.

公开(公告)号：US3721670A

公开(公告)日：1973-03-20

申请号：US3721670D

申请日：1971-04-05

申请人： MORTON NORWICH PRODUCTS INC

发明人： WRIGHT G ,  YU C

IPC分类号： C07D215/42 ,  C07D471/04 ,  C07D55/08

CPC分类号： C07D471/04 ,  C07D215/42

摘要： NOVEL 3-SUBSTITUTED-AS-TRIAZINO(5,6-C)QUINOLINES OF THE FORMULA:

3-R-AS-TRIAZINO(5,6-C)QUINOLINE

WHEREIN R IS CHLORO, AMINO, 2-HYDROXYETHYLAMINO, METHOXY, OR DIALLYLAMINO ARE USEFUL AS ANTIFUNGAL AGENTS.

公开(公告)号：US3622578A

公开(公告)日：1971-11-23

申请号：US3622578D

申请日：1969-04-01

申请人： DOW CHEMICAL CO

发明人： RIGTERINK RAYMOND H

IPC分类号： A01N57/16 ,  C07D253/08 ,  C07F9/6521 ,  C07D55/08

CPC分类号： C07D253/08 ,  A01N57/16 ,  C07F9/65218

摘要： Alkylthio-, alkylsulfinyl- and alkylsulfonyl-substituted S-((4oxo-1,2,3-benzotriazin-3(4H)-yl)methyl) phosphorothioates and phosphorodithioates of the formula

AND METHODS EMPLOYING AND COMPOSITIONS COMPRISING THESE SUBSTITUTED PHOSPHOROTHIOATES AND SUBSTITUTED PHOSPHORODITHIOATES FOR CONTROLLING PARASITES, ESPECIALLY ARTHROPOD PESTS SUCH AS INSECTS AND ARACHNIDS. In the above and succeeding formulas in the present specification and claims, Z represents oxygen or sulfur; R represents loweralkylthio, loweralkylsulfinyl or loweralkylsulfonyl; and each R'' independently represents loweralkyl.

公开(公告)号：US3772279A

公开(公告)日：1973-11-13

申请号：US3772279D

申请日：1972-07-24

申请人： SANDOZ AG

发明人： KATHAWALA F

IPC分类号： C07C243/38 ,  C07D253/08 ,  C07D55/08

CPC分类号： C07D253/08 ,  C07C243/38

摘要： DISCLOSED ARE COMPOUNDS OF THE CLASS OF 4-OXO-1,2,3BENZOTRIAZINE-3-PROPIONIC ACIDS AND ESTERS THEREOF, E.G. 6CHLORO-4-OXO-1,2,3-BENZOTRIAZINE-3-B-PROPIONIC ACID ETHYL ESTER. THE COMPOUNDS HAVE PHARMACOLOGICAL ACTIVITY IN ANIMALS, E.G. ANTI-INFLAMMATORY ACTIVITY. THE COMPOUNDS MAY BE PREPARED, FOR EXAMPLE, BY ADDITION TO THE CORRESPONDING 3-UNSUBSTITUTED COMPOUNDS AND BY REACTION OF AN ANTHRANIL AMIDE WITH SODIUM NITRITE AND A STRONG INORGANIC ACID, E.G. SULFURIC ACID. THE ACID FORMS ARE PREFERABLY PREPARED FROM THE ESTERS IN A KNOWN MANNER.

公开(公告)号：US3757019A

公开(公告)日：1973-09-04

申请号：US3757019D

申请日：1972-06-22

申请人： CASSELLA FARBWERKE MAINKUR AG

发明人： STACHEL A ,  NITZ R ,  RESAG K ,  STACHEL I ,  BEYERLE R ,  SCHRAVEN E

IPC分类号： C07D253/08 ,  C07D55/08

CPC分类号： C07D253/08 ,  Y10S514/929

摘要： THE PRESENT INVENTION PERTAINS TO NEW, PHARMACOLOGICALLY VALUABLE BASICALLY SUBSTITUTED 1,2,3-BENZOTRIAZINE4(3H)-ONE DERIVATIVES HAVING EXCELLENT CORONARY DILATORY PROPERTIES AND WHICH HAVE THE STRUCTURAL FORMULA

4-(O=),3-((R2)M-C6H4-COO-CH(-CH2-R'')-CH2-),(R1)N-3,4-

DIHYDRO-1,2,3-BENZOTRIAZINE

WHEREIN R'' IS A RADICAL SELECTED FROM THE GROUP CONSISTING OF N-METHYLPIPERAZINO, N-PHENYPIPERAZINO AND N-TRIMETHOXYBENZOXYETHYLPIPERAZINO, SAID RADICAL BEING BOUND VIA A NITROGEN ATOM; R1 IS A LOWER ALKOXY GROUP HAVING 1-4 CARBON ATOMS WHICH MAY BE IN THE 6,7 OR 6,7,8-POSITION; R2 IS AN ALKOXY HAVING 1-4 CARBON ATOMS; M IS AN INTEGER SELECTED FORM 1,2 AND 3; AND N IS AN INTEGER SELECTED FROM THE GROUP CONSISTING OF 2 AND 3 AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF.

公开(公告)号：US3586680A

公开(公告)日：1971-06-22

申请号：US3586680D

申请日：1969-06-25

申请人： BAYER AG

发明人： MEISER WERNER ,  EUE LUDWIG ,  HACK HELMUTH ,  TIMMLER HELMUT ,  WEGLER RICHARD

IPC分类号： C07D253/06 ,  A01N43/707 ,  C07C281/18 ,  C07D253/075 ,  C07D55/08

CPC分类号： C07D253/075 ,  A01N43/707 ,  C07C281/18

摘要： 5-IMINO-1,2,4-TRIAZINES, I.E. 3-(ALKYLMERCAPTO, ALKYLAMINO AND DIALKYLAMINO)-4-(ALKYL AND AMINO)-5-IMINO-6-(OPTIONALLY CHLORO SUBSTITUTED)-PHENYL-1,2,4-TRIAZINES, WHICH POSSESS HERBICIDAL PROPERTIES, AND WHICH MAY BE PRODUCED BY CONVENTIONAL METHODS.