公开(公告)号：US4744812A

公开(公告)日：1988-05-17

申请号：US707190

申请日：1985-03-04

Applicant: Adolf Parg ,  Bruno Wuerzer ,  Gerhard Hamprecht

Inventor： Adolf Parg ,  Bruno Wuerzer ,  Gerhard Hamprecht

IPC: C07C309/63 ,  A01N43/08 ,  C07C43/29 ,  C07C43/295 ,  C07C43/315 ,  C07C59/66 ,  C07C67/00 ,  C07C69/708 ,  C07C69/712 ,  C07C201/00 ,  C07C205/38 ,  C07C205/42 ,  C07C205/59 ,  C07C235/06 ,  C07C255/37 ,  C07C255/53 ,  C07C271/06 ,  C07C301/00 ,  C07C307/02 ,  C07C317/00 ,  C07C317/04 ,  C07C317/22 ,  C07C317/46 ,  C07C323/20 ,  C07C323/52 ,  C07C323/56 ,  C07C323/60 ,  C07C323/67 ,  C07C327/22 ,  C07C333/02 ,  C07D307/12 ,  C07D317/24 ,  C07D339/06 ,  C07F7/18 ,  C07F9/09 ,  C07F9/165 ,  C07F9/24 ,  C07C143/68 ,  C07C147/06 ,  C07C147/14

CPC classification number: C07F9/2429 ,  C07C205/38 ,  C07C205/42 ,  C07C205/44 ,  C07C255/00 ,  C07C317/00 ,  C07C323/00 ,  C07C323/52 ,  C07C327/22 ,  C07C43/295 ,  C07C43/315 ,  C07C59/66 ,  C07D307/12 ,  C07D317/24 ,  C07D339/06 ,  C07F7/1852 ,  C07F9/094 ,  C07F9/1653

Abstract: Substituted diphenyl ethers of the formula ##STR1## where Z.sub.1, Z.sub.2 and Z.sub.3 are hydrogen, halogen, nitro, cyano, carboxyl, alkyl, haloalkyl, alkoxy, haloalkoxy, alkylmercapto, haloalkylmercapto, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl or haloalkylsulfonyl, Z.sub.4 is hydrogen, cyano, alkyl, alkoxy, acetoxy or alkylmercapto, Y is hydrogen, halogen, cyano or nitro, X is oxygen, sulfur, sulfinyl or sulfonyl, and A is hydrogen, unsubstituted or substituted alkyl ##STR2## and can also be sulfonyl ##STR3## when X is oxygen, and, when Z.sub.4 is alkoxy or alkylmercapto, can also be a methylene chain --(CH.sub.2).sub.m -- by which the radicals Z.sub.4 --CH--X-- are bonded to form a ring, R.sub.1 is hydrogen, methyl, ethyl or n-propyl, R.sub.2 is cyano, methoxy, ethoxy or ##STR4## where B is OH, ONa, O--alkyl, unsubstituted or substituted phenoxy, --NH.sub.2, --NH--alkyl or --N(alkyl).sub.2, n is 1, 2 or 3, R.sub.3 and R.sub.4 are hydrogen, halogen, methyl, nitro, cyano, methoxy, carboxyl, trifluoromethyl or an O-propionic acid methyl ester group, R.sub.5 is methyl, ethyl, propyl, chloromethyl, dichloromethyl, trichloromethyl, methoxymethyl, phenyl, nitro-substituted phenyl, alkyl-substituted phenyl or .alpha.-2,4-dichlorophenoxyethyl, R.sub.6 and R.sub.7 are hydrogen, alkyl, alkoxyalkyl, dihalophenyl, cyclohexyl or methoxy, R.sub.8, R.sub.9 and R.sub.10 are methyl, ethyl, n-propyl or n-butyl, R.sub.11 and R.sub.12 are methoxy, ethoxy, thiomethyl, thioethyl, thio-n-propyl, N,N-dimethylamino or N,N-diethylamino, R.sub.13 is methyl, ethyl, phenyl or trifluoromethyl, R.sub.14 and R.sub.15 are hydrogen, methyl, ethyl, n-propyl, isopropyl, n-butyl, n-hexyl, n-heptyl, methoxy, ethoxy or isopropoxy, and m is 2 or 3; and herbicides containing these compounds.

Abstract translation: 下式的取代的二苯醚其中Z1，Z2和Z3是氢，卤素，硝基，氰基，羧基，烷基，卤代烷基，烷氧基，卤代烷氧基，烷基巯基，卤代烷基巯基，烷基亚磺酰基，卤代烷基亚磺酰基，烷基磺酰基或卤代烷基磺酰基，Z4是氢 氰基，烷基，烷氧基，乙酰氧基或烷基巯基，Y是氢，卤素，氰基或硝基，X是氧，硫，亚磺酰基或磺酰基，A是氢，未取代或取代的烷基， 并且当X是氧时也可以是磺酰基，并且当Z4是烷氧基或烷基巯基时，也可以是基团Z4-CH-X-被键合形成的亚甲基链 - （CH 2）m - 环，R 1是氢，甲基，乙基或正丙基，R 2是氰基，甲氧基，乙氧基或者其中B是OH，ONa，O-烷基，未取代或取代的苯氧基，-NH 2，-NH-烷基或 -N（烷基）2，n为1,2或3，R3和R4为氢，卤素，甲基，硝基，氰基，甲氧基，羧基，三氟甲基或O-丙酸甲酯 酯基，R5是甲基，乙基，丙基，氯甲基，二氯甲基，三氯甲基，甲氧基甲基，苯基，硝基取代的苯基，烷基取代的苯基或α-2,4-二氯苯氧基乙基，R6和R7是氢，烷​​基，烷氧基烷基，二卤代苯基 ，环己基或甲氧基，R8，R9和R10是甲基，乙基，正丙基或正丁基，R11和R12是甲氧基，乙氧基，硫代甲基，硫代乙基，硫代正丙基，N，N-二甲基氨基或N，N - 二乙基氨基，R 13是甲基，乙基，苯基或三氟甲基，R 14和R 15是氢，甲基，乙基，正丙基，异丙基，正丁基，正己基，正庚基，甲氧基，乙氧基或异丙氧基，m是 2或3; 和含有这些化合物的除草剂。

公开(公告)号：US4704467A

公开(公告)日：1987-11-03

申请号：US940995

申请日：1986-12-12

Applicant: Peter K. Wehrenberg

Inventor： Peter K. Wehrenberg

IPC: C07C20060101 ,  C07C317/44 ,  C07C149/40 ,  C07C147/14 ,  C07C147/107

CPC classification number: C07C317/00 ,  C07C323/00

Abstract: A method of preparing a compound of the formula ##STR1## wherein R is alkyl, R.sub.1 is alkyl or aryl and X is halogen or nitro comprising reacting ##STR2## wherein R and X are as defined above with a mercaptan having the formula R-SH in the presence of an inorganic base, a phase transfer catalyst and a non-polar aprotic solvent.

Abstract translation: 一种制备下式化合物的方法，其中R是烷基，R 1是烷基或芳基，X是卤素或硝基，其中R和X如上所定义，与具有式R-SH的硫醇反应 在无机碱，相转移催化剂和非极性非质子溶剂的存在下进行。

公开(公告)号：US4419523A

公开(公告)日：1983-12-06

申请号：US262576

申请日：1981-05-11

Applicant: Ferenc M. Pallos ,  Edmund J. Gaughan

Inventor： Ferenc M. Pallos ,  Edmund J. Gaughan

IPC: C07D319/06 ,  C07F9/38 ,  C07C147/14

CPC classification number: C07D319/06 ,  C07F9/3808

Abstract: N-(substituted benzenesulfonyl) carbamates as new compositions of matter useful as active herbicidal antidotes to protect against and decrease crop injury when used with a thiocarbamate herbicide when applied in various methods; improved herbicidal compositions and utility of said compositions to protect against and decrease phytotoxic crop injury when employing thiocarbamate herbicides and a two-part herbicide system comprising a first-part of one or more thiocarbamate herbicide and a second part of an effective antidote therefor compound said antidote compounds of the class N-benzene sulfonyl carbamates having the formula ##STR1## wherein X is hydrogen, bromo, chloro, methoxy, trifluoromethyl, and methyl; n is an integer from 1 to 3 inclusive, provided that when X is bromo, trifluoromethyl, or methoxy, n is 1; and R is selected from alkyl, haloalkyl wherein halo is chloro or fluoro, alkenyl, haloalkenyl and wherein halo is chloro, alkynyl, trifluoroacetamidomethyl, dialkylamino cyanoalkylthioalkyl, phosphonomethyl, lower alkyl substituted phenyl, 4-chlorophenylthiomethyl, alkoxyalkyl, alkylthioalkyl, cyanoalkyl, alkoxycarbonylalkyl, formamidoalkyl, alkoxycarbonylalkenyl, alkylcarbonylalkyl, 1,3-dioxacyclohexane-5,5-methylene, phenyl, chlorophenyl, benzyl, 4-chlorobenzyl, 4-methoxybenzyl, 3-pyridylmethyl, phenoxyethyl, 3-phenylpropyn-2-yl, methylthioacetimino, acetone imino and benzaldimino.This is a division, of application Ser. No. 108,889, filed Dec. 31, 1979 U.S. Pat. No. 4,293,701 which is a division of Ser. No. 721,721 Sept. 13, 1976, U.S. Pat. No. 4,230,874; which in turn is a continuation-in-part of Ser. No. 619,114 Oct. 2, 1975, abandoned.

Abstract translation: N-（取代的苯磺酰基）氨基甲酸酯作为活性除草剂的新组合物，用于当以各种方法施用时用于与硫代氨基甲酸酯除草剂一起使用时防止和减少作物损伤; 改进的除草组合物和所述组合物在使用硫代氨基甲酸酯除草剂时防止和减少植物毒性作物损伤的效用以及包含一种或多种硫代氨基甲酸酯除草剂的第一部分的两部分除草剂系统和其中一种有效解毒剂的第二部分化合物所述解毒剂 具有式“IMAGE”的N-苯磺酰基氨基甲酸酯类化合物，其中X是氢，溴，氯，甲氧基，三氟甲基和甲基; n为1〜3的整数，条件是当X为溴，三氟甲基或甲氧基时，n为1; 其中卤素为氯或氟，烯基，卤代烯基，其中卤素为氯，炔基，三氟乙酰胺基甲基，二烷基氨基氰基烷基硫代烷基，膦酰基甲基，低级烷基取代的苯基，4-氯苯硫基甲基，烷氧基烷基，烷硫基烷基，氰基烷基，烷氧羰基烷基， 甲酰氨基烷基，烷氧基羰基烯基，烷基羰基烷基，1,3-二氧杂环己烷-5,5-亚甲基，苯基，氯苯基，苄基，4-氯苄基，4-甲氧基苄基，3-吡啶基甲基，苯氧基乙基，3-苯基丙炔-2-基，甲硫基乙酰亚氨基， 和苯达拉霉素。

公开(公告)号：US4227013A

公开(公告)日：1980-10-07

申请号：US35705

申请日：1979-05-03

Applicant: Howard C. Haas ,  Robert D. Moreau

Inventor： Howard C. Haas ,  Robert D. Moreau

IPC: C07C317/04 ,  C07C69/34 ,  C07C102/00 ,  C07C147/14

CPC classification number: C07C317/04

Abstract: A process for preparing polyfunctional methylene-bridged compounds is disclosed. A difunctional methylene-bridged compound having acidic protons and having the formula X--CH.sub.2 --X is reacted with an alkali metal in the presence of a disubstituted formamide to provide a methylene-bridged polyfunctional compound having the formula ##STR1## wherein X is an electron-withdrawing group such as --CONH.sub.2, --COOR or --SO.sub.2 R where R is alkyl. The polyfunctional compounds prepared by the process of the present invention are useful in the production of metal complexing or sequestering agents, acidulents, cross-linking agents for polymeric reactions and in applications where a polyfunctional compound is desirably employed.

Abstract translation: 公开了制备多官能亚甲基桥接化合物的方法。 具有酸性质子且具有式X-CH 2 -X的双官能亚甲基桥接化合物在二取代甲酰胺存在下与碱金属反应，得到具有下式的亚甲基桥连多官能化合物，其中X是电子 - 取代基如-CONH 2，-COOR或-SO 2 R，其中R是烷基。 通过本发明的方法制备的多官能化合物可用于生产金属络合剂或螯合剂，酸性剂，聚合反应的交联剂和期望使用多官能化合物的应用。

公开(公告)号：US4199531A

公开(公告)日：1980-04-22

申请号：US840806

申请日：1977-10-11

Applicant: Shinji Terao ,  Kaneyoshi Kato

Inventor： Shinji Terao ,  Kaneyoshi Kato

IPC: C07C37/055 ,  C07C39/19 ,  C07C39/225 ,  C07C46/00 ,  C07C46/02 ,  C07C46/06 ,  C07C46/10 ,  C07C50/28 ,  C07C317/18 ,  C07D303/22 ,  C07D303/24 ,  C07D303/32 ,  C07C147/06 ,  C07C43/22 ,  C07C147/14

CPC classification number: C07D303/22 ,  C07C317/18 ,  C07C37/055 ,  C07C46/00 ,  C07C46/02 ,  C07C46/06 ,  C07C46/10 ,  C07C50/28 ,  C07D303/24 ,  C07D303/32

Abstract: A novel method for producing hydroquinone and quinone derivatives by a regio- and stereo-specific coupling reaction of hydroquinone derivative having a terminal activated (poly)prenyl side chain with a prenyl derivative. This method can provide in good yield various hydroquinone and quinone derivatives having any prenyl length of the side chain.

Abstract translation: 一种通过具有末端活化（聚）异戊烯基侧链与异戊烯基衍生物的氢醌衍生物的区域和立体特异性偶合反应制备氢醌和醌衍生物的新方法。 该方法可以很好地提供具有侧链的任何异戊烯基长度的各种氢醌和醌衍生物。

公开(公告)号：US4064178A

公开(公告)日：1977-12-20

申请号：US701383

申请日：1976-06-30

Applicant: George G. Ecke

Inventor： George G. Ecke

IPC: A01N41/10 ,  C07C317/00 ,  C07C317/14 ,  C07C147/14 ,  A01N9/14

CPC classification number: C07C323/00 ,  A01N41/10 ,  C07C317/00

Abstract: Bis(4-chlorophenyl)methyl methyl sulfoxide which effectively controls the harmful effects upon plants of plant pests, particularly Mexican Bean Beetle and Southern Army Worm, as well as certain fungi and bacteria is disclosed; as well as, the method of controlling the harmful effects of plant pests with the compound.

Abstract translation: 披露了有效控制植物害虫特别是墨西哥豆甲虫和南方虫虫对植物有害影响的双（4-氯苯基）甲基甲基亚砜，以及某些真菌和细菌; 以及用化合物控制植物害虫的有害影响的方法。

公开(公告)号：US3897492A

公开(公告)日：1975-07-29

申请号：US37132973

申请日：1973-06-18

Applicant: STAUFFER CHEMICAL CO

Inventor： TILLES HARRY ,  MACDONALD ALAN A

IPC: A01N47/08 ,  C07C67/00 ,  C07C325/00 ,  C07C333/02 ,  C07C381/00 ,  C07C381/14 ,  C07C103/76 ,  C07C147/14

Abstract: Intermediate compounds and the process of manufacturing herbicidally active sulfoxide and sulfone compounds are described herein. The intermediate compounds have the following generic formula:

WHEREIN R is selected from the group consisting of halophenyl, phenalkyl, substituted phenalkyl, wherein said substituents can be selected from halogen, alkyl and haloalkyl; R1 and R2 can be the same or different and can be selected from the group consisting of lower alkyl, cycloalkyl, alkenyl, alkynyl and benzyl. The active compounds are made by reacting the intermediate compound with an oxidizing agent.

Abstract translation: 本文描述了中间体化合物和制备除草活性亚砜和砜化合物的方法。 中间体化合物具有以下通式：

公开(公告)号：US3896168A

公开(公告)日：1975-07-22

申请号：US36967673

申请日：1973-06-13

Applicant: STAUFFER CHEMICAL CO

Inventor： TILLES HARRY

IPC: C07C333/02 ,  C07C103/32 ,  C07C147/14

CPC classification number: C07C333/02

Abstract: Intermediate compounds useful for manufacturing herbicidally active sulfoxide compounds are described herein. The compounds have the following generic formula:

wherein R and R1 are lower alkyl; and R2 can be selected from the group consisting of phenyl and benzyl.

公开(公告)号：US3773838A

公开(公告)日：1973-11-20

申请号：US3773838D

申请日：1972-02-29

Applicant: INST PRZEMYSLU ORGANICZEGO

Inventor： ANDRUSKI R ,  JEDRASKA M ,  LICHTENSZTEJN H ,  LESZCZYNSKI Z

IPC: C07C317/04 ,  C07C20060101 ,  C07C317/00 ,  C07C147/14

CPC classification number: C07C317/00

Abstract: A METHOD OF PREPARING DIMETHYLSULPHOXIDE BY OXIDIZING DIMETHYL SULPHIDE BY HIGH CONCENTRATED (70-100%) SOLUTIONS OF ORGANIC HYDROPEROXIDES E.G. ISOPROPYLBENZENEHYDROPEROXIDE OR ETHYLBENZENE HYDROPEROXIDE. THE PROCESS IS CARRIED OUT AT TEMPERATURES OF 20* -80* C. IN A TWOPHASE SYSTEM; THE FIRST PHASE IS AN AQUEOUS SOLUTION (1-8 MOLES H2O/MOL DMS) WITH AN ACID REACTION IN WHICH THE HYDROGEN ION CONCENTRATION IS FROM 10-6 TO 1 G./DM.3 SOLUTION, WHILE THE SECOND PHASE IS AN ORGANIC PHASE. EXTRACTION OF DIMETHYLSUPHOXIDE FROM THE REACTION SOLUTION IS EFFECTED BY THE AQUEOUS PHASE AND ANY REMAINING DIMETHYLSULPHOXIDE IN THE ORGANIC PHASE IS OBTAINED BY MEANS OF WASHING WITH AN AQUEOUS SOLUTION OF THE SAME HYDROGEN ION CONCENTRATION AS BEFORE. THE EXTRACTS ARE DISTILLATED UNDER REDUCED PRESSURE GIVING PURE DIMETHYLSULPHOXIDE. THE RAFFINATE IS A READY PRODUCT OR CAN SERVE AS A RAW MATERIAL FOR FURTHER SYNTHESES.

公开(公告)号：US3737455A

公开(公告)日：1973-06-05

申请号：US3737455D

申请日：1971-01-21

Applicant: MERCK & CO INC

Inventor： SHEN T ,  JONES H ,  FORDICE M

IPC: A61K31/185 ,  C07C45/45 ,  C07C49/697 ,  C07C313/00 ,  C07C317/00 ,  C07C317/14 ,  C07D207/08 ,  C07D295/08 ,  C07D317/72 ,  C07C147/14

CPC classification number: C07D207/08 ,  C07C45/455 ,  C07C49/697 ,  C07C317/00 ,  C07C323/00 ,  C07C2602/08 ,  C07D317/72 ,  Y10S514/825

Abstract: NEW SUBSTITUTED INDENE ACIDS AND NON-TOXIC PHARMACEUTICALLY ACCEPTABLE AMIDES, ESTERS AND SALTS DERIVED THEREFROM. THE SUBSTITUTED INDENE ACIDS DISCLOSED HEREIN HAVE ANTI-INFLAMMATORY, ANTI-PYRETIC AND ANALGESIC ACTIVITY. ALSO INCLUDED HEREIN ARE METHODS OF PREPARING SAID INDENE ACID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS HAVING SAID INDENE ACID COMPOUNDS AS AN ACTIVE INGREDIENT AND METHODS OF TREATING INFLAMMATION BY ADMINISTERING THESE PARTICULAR COMPOSITIONS TO PATIENTS.