公开(公告)号：US08509903B2

公开(公告)日：2013-08-13

申请号：US12479067

申请日：2009-06-05

Applicant: Randall York ,  Scott Kokones ,  Keith Carlton ,  Alan Greszler

Inventor： Randall York ,  Scott Kokones ,  Keith Carlton ,  Alan Greszler

IPC: A61N1/36 ,  A61N1/3605 ,  A61N1/36014 ,  A61N1/40

CPC classification number: A61N1/36103 ,  A61N1/0534 ,  A61N1/0551 ,  A61N1/3605 ,  A61N1/36067 ,  A61N1/36082 ,  A61N1/3615

Abstract: Methods of neuromodulation in a live mammalian subject, such as a human patient. The method comprises applying an electrical signal to a target site in the nervous system, such as the brain, where the electrical signal comprises a series of pulses. The pulses includes a waveform shape that is more energy-efficient as compared to a corresponding rectangular waveform. Non-limiting examples of such energy-efficient waveforms include linear increasing, linear decreasing, exponential increasing, exponential decreasing, and Gaussian waveforms. Also described are apparatuses for neuromodulation and software for operating such apparatuses.

Abstract translation: 活体哺乳动物受试者（例如人类患者）中神经调节的方法。 该方法包括将电信号施加到诸如脑的神经系统中的目标部位，其中电信号包括一系列脉冲。 脉冲包括与对应的矩形波形相比更节能的波形形状。 这种能量效率波形的非限制性实例包括线性增加，线性递减，指数增加，指数减小和高斯波形。 还描述了用于神经调节的装置和用于操作这种装置的软件。