公开(公告)号：US09351817B1

公开(公告)日：2016-05-31

申请号：US14979579

申请日：2015-12-28

Applicant: Hee-Kyoung Woo

Inventor： Hee-Kyoung Woo

IPC: A61M5/307 ,  A61C19/08 ,  A61M5/30 ,  A61N5/067

CPC classification number: A61M5/3007 ,  A61M5/30

Abstract: Disclosed herein is a dental anesthetic injection device. The dental anesthetic injection device includes a laser generator, a pressure generator filled with a liquid for generating pressure, which expands due to a laser emitted by the laser generator, an anesthetic container which contains an anesthetic for dental use, a separation film disposed between the pressure generator and the anesthetic container and formed to be elastically deformable to transfer expansion energy of the pressure generator to the anesthetic container, and a replacement nozzle detachably coupled with the anesthetic container to be replaceable depending on an oral environment and configured to jet the anesthetic of the anesthetic container toward an oral cavity.

Abstract translation: 本文公开了一种牙科麻醉注射装置。 牙科麻醉注射装置包括激光发生器，填充有用于产生压力的液体的压力发生器，其由于激光发生器发射的激光而膨胀，包含用于牙科用途的麻醉剂的麻醉容器， 压力发生器和麻醉容器，并且形成为可弹性变形以将压力发生器的膨胀能量传递到麻醉容器;以及替换喷嘴，其与所述麻醉容器可拆卸地联接以根据口腔环境而被替换，并且构造成喷射麻醉剂 麻醉容器朝向口腔。

公开(公告)号：US09138535B2

公开(公告)日：2015-09-22

申请号：US13262553

申请日：2010-07-20

Applicant: Kathryn A. Bertleson ,  Justin M. Crank

Inventor： Kathryn A. Bertleson ,  Justin M. Crank

IPC: A61M5/307 ,  A61M5/145 ,  A61M37/00 ,  A61M5/30 ,  A61M5/34 ,  A61M25/00

CPC classification number: A61M25/0069 ,  A61M5/145 ,  A61M5/30 ,  A61M5/348 ,  A61M25/001 ,  A61M37/00 ,  A61M2025/0079 ,  A61M2205/502

Abstract: A needleless fluid injection system (100) including an injection console (102), an injection chamber in operative communication with the console, an injectate shaft (104) in operative communication with the console, which has an injection lumen extending from a proximal end to a distal end of the shaft, and at least one injection orifice extending through a wall of the injection lumen proximate the distal end of the shaft. The injection lumen can include a sealing cap (40) at its distal end.

Abstract translation: 一种无针注射系统（100），包括注射控制台（102），与控制台可操作地连通的注射室，与控制台可操作地连通的注射轴（104），其具有从近端延伸到 所述轴的远端以及至少一个注射孔，其延伸穿过所述注射腔的靠近所述轴的远端的壁。 注射腔可在其远端包括密封帽（40）。

公开(公告)号：US20120089114A1

公开(公告)日：2012-04-12

申请号：US13269421

申请日：2011-10-07

Applicant: Brian D. Hemond ,  Ian W. Hunter ,  Andrew J. Taberner ,  Dawn M. Wendell ,  N. Catherine Hogan

Inventor： Brian D. Hemond ,  Ian W. Hunter ,  Andrew J. Taberner ,  Dawn M. Wendell ,  N. Catherine Hogan

IPC: A61M5/31 ,  A61M5/307

CPC classification number: A61M5/30 ,  A61M5/24 ,  A61M5/46 ,  A61M5/486 ,  A61M2205/3331 ,  A61M2205/3358 ,  A61M2205/3368 ,  A61M2205/50 ,  A61M2205/8287

Abstract: A method for injecting a substance through a biological body surface includes providing a needle-free transdermal transport device configured to inject the substance through the surface. The substance is injected into the biological body with the transport device while a parameter of the injection is sensed and a servo-controller is used to dynamically adjust at least one injection characteristic based on the sensed parameter. The substance is injected for (i) a first time period during which a first portion of a volume of the substance is injected at a first injection pressure, and (ii) a second time period during which a remainder of the volume of the substance is injected at a second injection pressure. A viscosity of the substance may be determined, and a pressure calculated for injecting the substance based on the viscosity. The substance may be injected with the transport device by using the calculated pressure.

Abstract translation: 通过生物体表面注入物质的方法包括提供构造成通过所述表面注入物质的无针透皮输送装置。 当感测到注射的参数并且使用伺服控制器基于所感测的参数来动态地调整至少一个喷射特性时，将物质与输送装置一起注入生物体。 注射物质（i）在第一时间段期间，以第一注射压力注射物质的体积的第一部分，以及（ii）第二时间段，其中物质的剩余体积为 在第二注射压力下注射。 可以确定物质的粘度，并计算基于粘度注入物质的压力。 物质可以通过使用计算的压力与输送装置一起注入。

公开(公告)号：US20090234276A1

公开(公告)日：2009-09-17

申请号：US11792141

申请日：2005-12-01

Applicant: Warren L. Toles ,  Kevin Toles ,  Jules Poiron

Inventor： Warren L. Toles ,  Kevin Toles ,  Jules Poiron

IPC: A61M5/307

CPC classification number: G01F11/026 ,  A61M5/204 ,  A61M5/2053 ,  A61M5/30

Abstract: The present invention provides a needle-free injection device for delivering a medicament under pressure into an animal or human. The injection device includes an actuating device comprising: a gas tight chamber; a piston and rod assembly slidably received in the chamber and movable between a forward position and a rearward position; a gas charge in the chamber for urging the piston and rod assembly to the forward position; means for moving said piston and rod assembly against said gas charge into the rearward position; and a trigger for releasably retaining the piston and assembly in the rearward position. Also provided is a method and kit for using the device to administer a liquid through the skin of an animal or human.

Abstract translation: 本发明提供了一种用于将药物在压力下输送到动物或人体中的无针注射装置。 注射装置包括致动装置，其包括：气密室; 活塞和杆组件可滑动地容纳在腔室中并且可以在前进位置和后部位置之间移动; 在室中的气体装料，用于将活塞和杆组件推向前方位置; 用于使所述活塞和杆组件抵靠所述气体进料向后移动的装置; 以及用于将活塞和组件可释放地保持在向后位置的触发器。 还提供了一种用于使用该装置通过动物或人的皮肤施用液体的方法和试剂盒。

公开(公告)号：US06024724A

公开(公告)日：2000-02-15

申请号：US34226

申请日：1998-03-04

Applicant: Young Gyu Lee

Inventor： Young Gyu Lee

IPC: A61M5/142 ,  A61J1/05 ,  A61M5/14 ,  A61M5/152 ,  A61M5/307 ,  A61M37/00

CPC classification number: A61M5/152 ,  A61M2005/1405

Abstract: A liquid medicine injection device have a two-way injection amount controller. A collapsible tube is expanded with liquid medicine and forcibly discharges the medicine without allowing the medicine to remain in the tube due to the pressure of the fully expanded tube, thus preventing waste of the expensive medicine. The device, via the two-way injection amount controller, normally injects a primarily controlled amount of medicine into a patent at a steady rate and selectively and temporarily allows confluent medicine to join the primarily controlled amount of medicine in accordance with a patient's condition without giving additional syringe pain to the patient.

Abstract translation: 液体药物注射装置具有双向注射量控制器。 可折叠管用液体药物膨胀，并强制排出药物，而不会由于充分膨胀的管的压力而将药物保留在管中，从而防止昂贵药物的浪费。 该装置通过双向注射量控制器通常以稳定的速率将主要受控量的药物注入专利中，并且选择性地并且临时允许汇合的药物根据患者的状况加入主要控制量的药物而不给予 额外的注射器对患者的疼痛。

公开(公告)号：US5865796A

公开(公告)日：1999-02-02

申请号：US767374

申请日：1996-12-16

Applicant: Dennis E. McCabe

Inventor： Dennis E. McCabe

IPC: C12N15/09 ,  A61K48/00 ,  A61M5/20 ,  A61M5/28 ,  A61M5/30 ,  A61M5/307 ,  A61M5/31 ,  C12M1/00 ,  C12M3/00 ,  C12N15/63

CPC classification number: A61M5/3015 ,  C12M35/00 ,  A61M2005/005 ,  A61M5/2053

Abstract: A gas driven apparatus for accelerating particles coated with a genetic material into a target comprises a reservoir for releasably retaining a gas at a sufficiently high pressure to detach the particles from the surface of a sample cartridge and to carry the particles through the apparatus toward the target. When leaving the apparatus, the particles entrained in the gas stream pass through a substantially conical exit nozzle which causes the pattern of distribution of the particles to greatly expand. Methods for using the apparatus and for preparing the sample cartridges are also described.

Abstract translation: 用于将涂覆有遗传物质的颗粒加速到靶中的气体驱动装置包括用于以足够高的压力可释放地保持气体的储存器，以将颗粒从样品盒的表面分离并将颗粒通过装置运送到目标 。 当离开设备时，夹带在气流中的颗粒通过基本上圆锥形的出口喷嘴，其导致颗粒分布的图案大大地膨胀。 还描述了使用该设备和准备样品盒的方法。

公开(公告)号：US20120225094A1

公开(公告)日：2012-09-06

申请号：US13508930

申请日：2010-11-09

Applicant: Ira Sanders

Inventor： Ira Sanders

IPC: A61K39/08 ,  A61M5/00 ,  A61P11/00 ,  A61M5/307

CPC classification number: A61K38/4886

Abstract: Disclosed herein are compositions of neurotoxins and methods of their use for the treatment of sleep disordered breathing. In one embodiment of the present invention, a method of treating sleep breathing disorders comprising administering a therapeutically effective amount of Clostridia neurotoxin (CnT) or light chain thereof to a mammal in need thereof is disclosed.

Abstract translation: 本文公开了神经毒素的组合物及其用于治疗睡眠紊乱呼吸的方法。 在本发明的一个实施方案中，公开了一种治疗睡眠呼吸障碍的方法，包括向有需要的哺乳动物施用治疗有效量的梭菌神经毒素（CnT）或其轻链。

公开(公告)号：US20120157965A1

公开(公告)日：2012-06-21

申请号：US13257555

申请日：2010-03-19

Applicant: Paul Wotton ,  Peter L. Sadowski ,  John William Hayes

Inventor： Paul Wotton ,  Peter L. Sadowski ,  John William Hayes

IPC: A61M5/20 ,  A61M5/307

CPC classification number: A61M5/30 ,  A61K9/0019 ,  A61K9/0087 ,  A61K31/519 ,  A61K31/568 ,  A61M5/178 ,  A61M5/2033 ,  A61M5/3202 ,  A61M5/326 ,  A61M2005/2013 ,  A61M2005/2073 ,  A61M2005/3247

Abstract: Injection systems comprising a powered injector and one or more hazardous agents are disclosed.

Abstract translation: 公开了包括动力注射器和一种或多种危险剂的注射系统。

公开(公告)号：US20120095435A1

公开(公告)日：2012-04-19

申请号：US13269322

申请日：2011-10-07

Applicant: Ian W. Hunter ,  Andrew J. Taberner ,  N. Catherine Hogan

Inventor： Ian W. Hunter ,  Andrew J. Taberner ,  N. Catherine Hogan

IPC: A61M5/307

CPC classification number: A61M5/30 ,  A61M5/19 ,  A61M5/3015 ,  A61M5/427 ,  A61M37/0069 ,  A61M2205/332 ,  A61M2205/3331 ,  A61M2205/3561 ,  A61M2205/3584 ,  A61M2205/583

Abstract: A method for transferring a solid body across a surface of a biological body includes (i) applying an electrical input to a controllable electromagnetic actuator; (ii) producing with the electromagnetic actuator a mechanical force corresponding to the electrical input; and (iii) applying the mechanical force to a reservoir coupled at one end to a nozzle, the mechanical force producing a pressure within the reservoir, a magnitude of the pressure varying with the mechanical force and causing ejection of a fluid from the reservoir to drive the solid body into the biological body. A method for delivering a substance to a target body includes (i) positioning a needle-free injector proximate to a surface of the target body; (ii) injecting the substance into the target body; and (iii) while injecting, moving the needle-free injector along the surface, thereby sweeping the surface.

Abstract translation: 用于将固体转移到生物体的表面上的方法包括（i）将电输入施加到可控制的电磁致动器; （ii）用电磁致动器产生对应于电输入的机械力; 并且（iii）将机械力施加到在一端连接到喷嘴的储存器，所述机械力产生储存器内的压力，所述压力的大小随着机械力而变化并且使流体从储存器喷射到驱动 固体进入生物体。 将物质输送到目标体的方法包括：（i）将无针注射器定位在目标体的表面附近; （ii）将物质注入目标体内; 和（iii）在注射的同时沿着表面移动无针注射器，从而扫掠表面。

公开(公告)号：US20120065615A1

公开(公告)日：2012-03-15

申请号：US13232820

申请日：2011-09-14

Applicant: BROOKS BOYD ,  Jeffrey A. Schuster

Inventor： BROOKS BOYD ,  Jeffrey A. Schuster

IPC: A61M5/307

CPC classification number: A61M5/3007 ,  A61K31/404 ,  A61K39/395 ,  A61M5/30

Abstract: A needle free injector system and a method for delivering a formulation using this system are disclosed. The method comprises actuating a needle free injector to pressurize a liquid formulation and force the formulation through an orifice in a skin puncture phase followed by injection of the formulation during a delivery phase. The skin puncture phase is defined by a pressure profile vs. time curve after actuation which has a main pressure peak with a maximum pressure. The delivery phase occurs at a lower pressure than the maximum pressure of the main peak pressure. The device may have one or more orifices and pressurizing the formulation during the puncture phase and delivery phase to extrude the formulation through each orifice is structured so as to improve characteristics of needle free delivery.

Abstract translation: 公开了一种无针注射器系统和使用该系统递送制剂的方法。 该方法包括致动无针注射器以对液体制剂加压并迫使制剂穿过皮肤穿刺阶段中的孔口，然后在递送阶段期间注射制剂。 皮肤穿刺阶段由致动后的压力曲线与时间曲线限定，其具有最大压力的主压力峰值。 输送阶段发生在比主峰值压力的最大压力更低的压力下。 该装置可以具有一个或多个孔并且在穿刺阶段期间对制剂加压并且输送阶段以通过每个孔挤出制剂，以便改善无针送递的特性。