公开(公告)号：US06626893B2

公开(公告)日：2003-09-30

申请号：US09742885

申请日：2000-12-21

申请人： Rudolph W. Frey ,  James H. Burkhalter ,  Gary P. Gray ,  Neil Zepkin ,  George Richard Downes, Jr. ,  John E. McWhirter

发明人： Rudolph W. Frey ,  James H. Burkhalter ,  Gary P. Gray ,  Neil Zepkin ,  George Richard Downes, Jr. ,  John E. McWhirter

IPC分类号： A61F9007

CPC分类号： A61B3/113 ,  A61B2017/00694 ,  A61F9/008 ,  A61F9/00804 ,  A61F2009/00846 ,  A61F2009/00872 ,  A61F2009/00897

摘要： An ophthalmic laser system includes a laser beam delivery system and an eye tracker responsive to movement of the eye operable with a laser beam delivery system for ablating corneal material of the eye through placement of laser beam shot on a selected area of the cornea of the eye. The shots are fired in a sequence and pattern such that no laser shots are fired at consecutive locations and no consecutive shots overlap. The pattern is moved in response to the movement of the eye.

摘要翻译： 眼科激光系统包括激光束传送系统和眼睛跟踪器，其响应眼睛的运动，可操作的激光束传送系统用于通过放置在眼睛的角膜的选定区域上的激光束的放射来消除眼睛的角膜材料 。 射击以序列和图案被点燃，使得在连续的位置没有激光射击，并且没有连续的镜头重叠。 该图案响应于眼睛的移动而移动。

公开(公告)号：US06599305B1

公开(公告)日：2003-07-29

申请号：US09586273

申请日：2000-06-02

申请人： Vladimir Feingold

发明人： Vladimir Feingold

IPC分类号： A61F9007

CPC分类号： A61F2/1451 ,  A61F9/0133

摘要： A method and apparatus for correcting vision, including a corneal-pocket keratome device to create a corneal pocket and a lens to be inserted and retained in the corneal pocket to effect correction. The corneal-pocket keratome includes a drive unit having cutting head elements which contact the subject eye during corneal pocket formation. The cutting head elements may be removeable and may be disposable. The cutting head elements include a corneal restraint device, which may be a positioning ring to position an eyeball with the cornea protruding through the ring; a keratome blade assembly with a corneal-pocket blade; and may also include an applanation shoe surface to restrain the cornea, in addition or instead of the positioning ring. The applanation shoe may be pivotable away from the surgical area. The corneal-pocket blade may include a guide which travels with the blade. The blade assembly oscillates laterally while extending forward into the cornea to form the pocket, and the amplitude of the lateral oscillation is preferably increased as the blade goes beyond an opening incision into the cornea. Lenses for this invention preferably include a feature to impede accidental lens movement after the lens is disposed within the corneal pocket, which may be a swelling after insertion or a circumferential irregularity. Lenses may be of Fresnel or non-Fresnel type, and may employ annular changes in the index of refraction of the lens material, as well as changes in refractive shape which may be annular or not, to effect variations in focal length for relieving presbyopia, astigmatism, and combinations of those as well as myopia and hyperopia. Drive control and vacuum for the positioning ring are provided under user command by a control unit having user inputs.

摘要翻译： 一种用于矫正视力的方法和装置，包括角膜袋角膜成像装置，以产生角膜囊和待插入并保留在角膜袋中的透镜以进行矫正。 角膜囊角膜角膜包括具有切割头元件的驱动单元，其在角膜袋形成期间接触被检眼。 切割头元件可以是可移除的并且可以是一次性的。 切割头元件包括角膜约束装置，角膜约束装置可以是定位环，用于通过环突出角膜来定位眼球; 具有角膜袋刀片的角膜组件刀片组件; 并且还可以包括压平鞋表面以限制角膜，另外或代替定位环。 压扁鞋可以远离手术区域枢转。 角膜袋刀片可以包括与刀片一起行进的引导件。 叶片组件在向前延伸到角膜中而横向摆动以形成袋，并且横向振动的幅度优选地随刀片超过开口切口进入角膜而增加。 用于本发明的镜片优选地包括在透镜设置在角膜囊内之后阻止意外透镜移动的特征，其可以在插入之后膨胀或周向不规则。 透镜可以是菲涅尔或非菲涅尔型，并且可以采用透镜材料的折射率的环形变化以及可以是环形的或不是环形的折射形状的变化，以实现焦距的变化以减轻老视， 散光，以及这些以及近视和远视的组合。 由用户输入的控制单元在用户命令下提供定位环的驱动控制和真空。

公开(公告)号：US06562026B2

公开(公告)日：2003-05-13

申请号：US09852388

申请日：2001-05-09

申请人： Herrmann J. Glockler

发明人： Herrmann J. Glockler

IPC分类号： A61F9007

CPC分类号： A61F9/008 ,  A61B90/20 ,  A61F9/00804 ,  A61F2009/00872

摘要： The invention provides improved structures, systems, and methods for supporting the optical elements of a microscope relative to the optical train of a laser surgery system. As the field of view of the microscope is substantially fully determined by the position of the objective lens, the laser delivery optics and the microscope can be aligned with a target location of the patient's eye by accurately aligning just the objective lens with the delivery optics. By structurally separating the objective lens from the other optical components of the microscope, and by maintaining accurate alignment between the objective lens and the laser delivery optics with a simple, tight-tolerance support structure, the remaining optical components of the microscope can be allowed to “float” relative to the objective lens with a looser-tolerance without degrading the operator's ability to align, observe, and optically direct an ophthalmic laser procedure.

公开(公告)号：US06551336B2

公开(公告)日：2003-04-22

申请号：US09750151

申请日：2000-12-29

申请人： Masahiro Sugimura

发明人： Masahiro Sugimura

IPC分类号： A61F9007

CPC分类号： A61F9/013

摘要： A corneal surgical apparatus for incising a cornea of a patient's eye in a layered form includes: a blade; a rotating shaft; a bearing rotatably supporting the rotating shaft; a transmitting mechanism which converts rotation of the rotating shaft about a rotation center axis into oscillation in a direction perpendicular to the rotation center axis and transmits the oscillation to the blade; and a preventing mechanism which prevents moisture component from penetrating or infiltrating into a clearance between the rotating shaft and the bearing by controlling the rotation of the rotating shaft.

摘要翻译： 用于以分层形式切割患者眼睛的角膜的角膜手术装置包括：刀片; 旋转轴; 可旋转地支撑旋转轴的轴承; 传递机构，其将旋转轴的旋转绕旋转中心轴转动成与所述旋转中心轴垂直的方向振动，并将振动传递到所述叶片; 以及通过控制旋转轴的旋转来防止水分成分渗入或渗透到旋转轴和轴承之间的间隙中的防止机构。

公开(公告)号：US06824541B2

公开(公告)日：2004-11-30

申请号：US10233062

申请日：2002-08-30

申请人： Dmitri Boutoussov ,  Colette Cozean

发明人： Dmitri Boutoussov ,  Colette Cozean

IPC分类号： A61F9007

CPC分类号： H01S3/1022 ,  B23K26/0622 ,  H01S3/092 ,  H01S3/1024 ,  H01S3/1608 ,  H01S2302/00

摘要： A non Q-switched erbium laser operating on the I11/2→I13/2 transition produces laser output pulses characterized by a single spike containing approximately 90% of the energy, rather than a series of multiple spikes. The laser includes an optical gain medium with erbium being the lasing species, such as an erbium doped YAG rod. The gain medium is pumped with a flashlamp, with the voltage applied to the flashlamp and the duration of the applied voltage being carefully controlled to produce the single spike laser output. Depending upon the operating conditions, the full width half maximum (FWHM) of the spikes can be varied between 0.1 and 10 microseconds. The output of the erbium has fewer than 10 transverse modes. Output from the erbium laser may be directed onto corneal tissue in a preferred corneal sculpting procedure, in which the ablation rate is limited to no more than about 3 microns per laser pulse.

摘要翻译： 在I11 / 2-> I13 / 2转换器上工作的非Q开关铒激光器产生激光输出脉冲，其特征在于包含大约90％的能量的单个尖峰，而不是一系列多个尖峰。 激光器包括具有铒作为激光物质的光学增益介质，例如掺铒YAG棒。 增益介质用闪光灯泵浦，电压施加到闪光灯，并且小心地控制施加电压的持续时间以产生单个尖峰激光输出。 根据操作条件，尖峰的全宽度半最大值（FWHM）可以在0.1到10微秒之间变化。 铒的输出具有少于10个横向模式。 来自铒激光器的输出可以以优选的角膜雕刻方法被引导到角膜组织上，其中每个激光脉冲将烧蚀速率限制在不超过约3微米。

公开(公告)号：US06702809B1

公开(公告)日：2004-03-09

申请号：US09172976

申请日：1998-10-14

申请人： Carl F. Knopp ,  Jerzy Orkiszewski ,  Jan Wysopal ,  Hanna J. Hoffman

发明人： Carl F. Knopp ,  Jerzy Orkiszewski ,  Jan Wysopal ,  Hanna J. Hoffman

IPC分类号： A61F9007

CPC分类号： B23K26/04 ,  A61B3/113 ,  A61B2017/00694 ,  A61F9/008 ,  A61F9/00804 ,  A61F2009/0035 ,  A61F2009/00846 ,  A61F2009/00872 ,  B23K26/043 ,  B23K26/705

摘要： A method, apparatus and system for a transverse tracker is described that can greatly improve the accuracy, speed, range, reliability, versatility, safety, and efficacy of interventions such as laser microsurgery, particularly ophthalmic surgery, and industrial micromachining. The instrument and system disclosed are applicable to those situations wherein the positioning accuracy of laser lesions is critical, and/or whenever precise operations on a target or series of targets subject to random movement during a procedure are to be effected. The present invention provides means for stabilizing the motion of targets in a plane perpendicular to the axial direction, thus allowing an imaging system, diagnostics illumination, and/or laser beam to maintain a lock on the target area, regardless of its movement. The invention also provides means for recording eye movements in real time and in which data can be stored and manipulated for the purpose of compensating for lateral target motion by either hardware or software means. Unique attributes provided in the tracking system include means for (1) sensing contrast in recognizable large scale boundaries such as the change between the cornea/sclera interface (limbus), thereby to determine the absolute location and orientation of these boundaries, all without having to resort to digital sampling techniques and (2) dual mode operation of an electronic control system compatible with all analog technologies, thereby substantially increasing the speed of operations over other, comparable digital method. The tracking system of the invention is at least comprised of illumination sources, imaging optics, a sensor such as a position-sensitive detector, a movable optical element such as a mirror, a two-dimensional logic board, and a dedicated microprocessor, including appropriate signal processing firmware and software. Additional optics can be incorporated to provide interface with other assemblies such as depth tracking, target viewing and/or laser surgery subsystems. The system of the invention affords considerable flexibility in selecting particular components such as the illuminators, detectors and servo devices, which, in turn, allows broad application of this system to tracking tasks in diverse medical surgical, diagnostic, and industrial settings.

公开(公告)号：US06702807B2

公开(公告)日：2004-03-09

申请号：US09949085

申请日：2001-09-10

申请人： Gholam A. Peyman

发明人： Gholam A. Peyman

IPC分类号： A61F9007

CPC分类号： A61F2/145 ,  A61F2/1451 ,  A61F9/00812 ,  A61F9/00819 ,  A61F9/013 ,  A61F2009/00872 ,  A61F2009/0088

摘要： A method of correcting the refractive error in a cornea of an eye, including forming a flap in the surface of the cornea, and moving the flap to expose first and second internal surfaces of the cornea. An implant is positioned adjacent the first internal surface, at least a portion of the implant having refractive properties and held adjacent the first internal surface using a tool. At least a portion of the implant is ablated with a light emitting device, when the implant is positioned on the first exposed surface of the cornea and being held by the instrument. The flap is then repositioned over the implant.

摘要翻译： 一种校正眼睛角膜中的折射误差的方法，包括在角膜表面形成瓣片，以及移动瓣片以暴露角膜的第一和第二内表面。 植入物定位成邻近第一内表面，植入物的至少一部分具有折射性质并且使用工具保持在第一内表面附近。 当植入物定位在角膜的第一暴露表面上并由仪器保持时，用发光器件消融植入物的至少一部分。 然后将瓣片重新定位在植入物上。

公开(公告)号：US06562027B2

公开(公告)日：2003-05-13

申请号：US09741132

申请日：2000-12-19

申请人： Francis E. O'Donnell, Jr.

发明人： Francis E. O'Donnell, Jr.

IPC分类号： A61F9007

CPC分类号： A61F9/008 ,  A61F9/00804 ,  A61F2009/00855 ,  A61F2009/00872 ,  A61F2009/00882

摘要： A method for enhancing the accuracy of PRK wherein a UV power meter is placed in the optical path of the laser beam. In one preferred embodiment, the power meter is placed distal to the last optical element so that any optical degradation that affects laser performance is taken into account. The meter consists of a UV-B cube and a pulnix camera with a software package. The meter is used to monitor the fluence of each laser pulse. The power meter is used to size each pulse and to quantify the energy in each pulse. Sensing means is employed to measure intraoperative pulse-to-pulse energy during photorefractive keratectomy (PRK), using said data in conjunction with the location of the pulse within the ablation zone to determine the cumulative energy thus being achieved, and adjusting said laser to treat more or less at each point based upon the difference between the ideal cumulative energy map and the observed cumulative energy map derived from intraoperative power determination.

摘要翻译： 一种提高PRK精度的方法，其中将UV功率计置于激光束的光路中。 在一个优选实施例中，功率计位于最后一个光学元件的远侧，以便考虑影响激光器性能的任何光学劣化。 该仪表由一个UV-B立方体和一个带软件包的pulnix摄像机组成。 该仪表用于监测每个激光脉冲的能量密度。 功率计用于对每个脉冲进行定标，并对每个脉冲中的能量进行量化。 使用感测手段来测量光折射角膜切除术（PRK）期间的术中脉冲 - 脉冲能量，使用所述数据结合消融区域内的脉冲位置来确定由此实现的累积能量，并且调整所述激光治疗 基于理想累积能量图与从术中功率确定导出的观察到的累积能量图之间的差异，在每个点上或多或少地。

公开(公告)号：US06551307B2

公开(公告)日：2003-04-22

申请号：US09843141

申请日：2001-04-27

申请人： Gholam A. Peyman

发明人： Gholam A. Peyman

IPC分类号： A61F9007

CPC分类号： A61F2/145 ,  A61F2/147 ,  A61F9/008 ,  A61F9/00804 ,  A61F9/00806 ,  A61F9/00812 ,  A61F9/00819 ,  A61F9/00836 ,  A61F9/013 ,  A61F2009/00872 ,  A61F2009/0088

摘要： A method of modifying a cornea of an eye, including the steps of separating an internal portion of the cornea into first and second internal corneal surfaces. Ocular material is then inserted in-between the first and second corneal surfaces. A flap is formed on the surface of the cornea and moved to expose a third internal corneal surface, which is ablated with a laser.

摘要翻译： 一种改变眼睛角膜的方法，包括将角膜的内部分离成第一和第二内角膜表面的步骤。 然后将眼部材料插入第一和第二角膜表面之间。 角膜形成在角膜的表面上并移动以暴露第三内角膜表面，其被激光烧蚀。

公开(公告)号：US06398788B1

公开(公告)日：2002-06-04

申请号：US09535267

申请日：2000-03-23

申请人： Harish Makker ,  Shih-Liang S. Yang ,  Daniel G. Brady ,  Robert E. Glick

发明人： Harish Makker ,  Shih-Liang S. Yang ,  Daniel G. Brady ,  Robert E. Glick

IPC分类号： A61F9007

CPC分类号： A61F2/1675 ,  A61F2/1664

摘要： Apparatus for inserting intraocular lenses (IOLs) into eyes include a hollow tube including a material and having an interior wall defining a hollow space through which an IOL is passed and an outlet through which the IOL is passed from the hollow space into an eye, and a lubricity enhancing component physically secured to said hollow tube and concentrated at or near the interior wall in an amount effective to facilitate the passage of the IOL through the hollow space.

摘要翻译： 用于将眼内透镜（IOL）插入眼睛的装置包括：中空管，其包括材料，并且具有限定中空空间的内壁，IOL通过该中空空间和IOL从中空空间穿过眼睛的出口;以及 润滑性增强部件物理地固定到所述中空管上并且以有效促进IOL通过中空空间的量在内壁或其附近集中。