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公开(公告)号：US11946089B2
公开(公告)日：2024-04-02
申请号：US17592915
申请日：2022-02-04
发明人： Aaron Argyros , Trisha Barrett
IPC分类号： C12P7/06 , C12N9/00 , C12N9/02 , C12N9/04 , C12N9/06 , C12N9/10 , C12N9/34 , C12N9/50 , C12N9/60 , C12N15/52 , C12P7/10
CPC分类号： C12P7/06 , C12N9/0004 , C12N9/0006 , C12N9/0008 , C12N9/0016 , C12N9/1029 , C12N9/2428 , C12N9/50 , C12N9/60 , C12N9/93 , C12N15/52 , C12Y104/01002 , C12Y104/01004 , C12Y104/01014 , C12Y603/01002 , C12Y603/04006 , C12P7/10 , C12Y101/01001 , C12Y101/01002 , C12Y102/0101 , C12Y197/01004 , C12Y203/01054 , C12Y302/01003 , C12Y304/23041 , Y02E50/10
摘要： The present invention provides for a mechanism to reduce glycerol production and increase nitrogen utilization and ethanol production of recombinant microorganisms. One aspect of this invention relates to strains of S. cerevisiae with reduced glycerol productivity that get a kinetic benefit from higher nitrogen concentration without sacrificing ethanol yield. A second aspect of the invention relates to metabolic modifications resulting in altered transport and/or intracellular metabolism of nitrogen sources present in corn mash.
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2.发明申请METHODS FOR REGULATING NITROGEN METABOLISM DURING THE PRODUCTION OF ETHANOL FROM CORN BY METABOLICALLY ENGINEERED YEAST STRAINS 审中-公开通过代谢工程的YEAST菌株从玉米生产乙醇中调节氮代谢的方法公开(公告)号：US20160017377A1
公开(公告)日：2016-01-21
申请号：US14771831
申请日：2014-03-13
发明人： Aaron Argyros , Trisha Barrett
CPC分类号： C12P7/06 , C12N9/0004 , C12N9/0006 , C12N9/0008 , C12N9/0016 , C12N9/1029 , C12N9/2428 , C12N9/50 , C12N9/93 , C12N15/52 , C12P7/10 , C12Y101/01001 , C12Y101/01002 , C12Y102/0101 , C12Y104/01002 , C12Y104/01004 , C12Y104/01014 , C12Y197/01004 , C12Y203/01054 , C12Y302/01003 , C12Y304/23041 , C12Y603/01002 , C12Y603/04006 , Y02E50/17
摘要： The present invention provides for a mechanism to reduce glycerol production and increase nitrogen utilization and ethanol production of recombinant microorganisms. One aspect of this invention relates to strains of S. cerevisiae with reduced glycerol productivity that get a kinetic benefit from higher nitrogen concentration without sacrificing ethanol yield. A second aspect of the invention relates to metabolic modifications resulting in altered transport and/or intracellular metabolism of nitrogen sources present in com mash.
摘要翻译： 本发明提供减少甘油产生并增加重组微生物的氮利用和乙醇生产的机制。 本发明的一个方面涉及具有降低的甘油生产力的酿酒酵母菌株，其从更高的氮浓度获得动力学益处而不牺牲乙醇产量。 本发明的第二方面涉及导致存在于粉碎中的氮源的运输和/或细胞内代谢改变的代谢修饰。
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公开(公告)号：US20240360484A1
公开(公告)日：2024-10-31
申请号：US18443045
申请日：2024-02-15
发明人： Aaron Argyros , Trisha Barrett
IPC分类号： C12P7/06 , C12N9/00 , C12N9/02 , C12N9/04 , C12N9/06 , C12N9/10 , C12N9/34 , C12N9/50 , C12N9/60 , C12N15/52 , C12P7/10
CPC分类号： C12P7/06 , C12N9/0004 , C12N9/0006 , C12N9/0008 , C12N9/0016 , C12N9/1029 , C12N9/2428 , C12N9/50 , C12N9/60 , C12N9/93 , C12N15/52 , C12Y104/01002 , C12Y104/01004 , C12Y104/01014 , C12Y603/01002 , C12Y603/04006 , C12P7/10 , C12Y101/01001 , C12Y101/01002 , C12Y102/0101 , C12Y197/01004 , C12Y203/01054 , C12Y302/01003 , C12Y304/23041 , Y02E50/10
摘要： The present invention provides for a mechanism to reduce glycerol production and increase nitrogen utilization and ethanol production of recombinant microorganisms. One aspect of this invention relates to strains of S. cerevisiae with reduced glycerol productivity that get a kinetic benefit from higher nitrogen concentration without sacrificing ethanol yield. A second aspect of the invention relates to—metabolic modifications resulting in altered transport and/or intracellular metabolism of nitrogen sources present in corn mash.
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