公开(公告)号：US11788048B2

公开(公告)日：2023-10-17

申请号：US16646804

申请日：2018-09-14

Applicant: Life Technologies Corporation

Inventor： Stephan Kaiser

IPC: B01F27/00 ,  C12M1/06 ,  C12M1/00 ,  B01F27/054 ,  B01F27/072 ,  B01F27/2124 ,  B01F27/1125 ,  B01F35/513 ,  B01F101/44

CPC classification number: C12M27/02 ,  B01F27/054 ,  B01F27/0727 ,  B01F27/11251 ,  B01F27/2124 ,  B01F35/513 ,  C12M23/26 ,  B01F2101/44

Abstract: The present set of embodiments relate to a system, method, and apparatus for culturing cells within a cell culture vessel having a mixing element. The cell culture system includes a flexible portion and a mixing element disposed therein. The mixing element includes a suspended foldable portion. The system is configured to reduce shear stress on cells without compromising mixing efficiency. This reduction is accomplished by using a mixing element having a large surface area allowing for reduced rotational speeds. The system is collapsible for ease of transport and disposal. The flexible portion collapses and the foldable portion folds to minimize the volume of the system while not in operation.

公开(公告)号：US20230407226A1

公开(公告)日：2023-12-21

申请号：US18458867

申请日：2023-08-30

Applicant: Life Technologies Corporatin

Inventor： Stephan Kaiser

IPC: C12M1/06 ,  C12M1/00 ,  B01F27/054 ,  B01F27/072 ,  B01F27/2124 ,  B01F27/1125 ,  B01F35/513

CPC classification number: C12M27/02 ,  C12M23/26 ,  B01F27/054 ,  B01F27/0727 ,  B01F27/2124 ,  B01F27/11251 ,  B01F35/513 ,  B01F2101/44

Abstract: The present set of embodiments relate to a system, method, and apparatus for culturing cells within a cell culture vessel having a mixing element. The cell culture system includes a flexible portion and a mixing element disposed therein. The mixing element includes a suspended foldable portion. The system is configured to reduce shear stress on cells without compromising mixing efficiency. This reduction is accomplished by using a mixing element having a large surface area allowing for reduced rotational speeds. The system is collapsible for ease of transport and disposal. The flexible portion collapses and the foldable portion folds to minimize the volume of the system while not in operation.