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公开(公告)号：US20240115326A1
公开(公告)日：2024-04-11
申请号：US18280364
申请日：2022-03-20
发明人： Sharon BEN YEHUDA , Ram BEN YEHUDA , Semion KHAIT
CPC分类号： A61B34/20 , A61B5/067 , A61B5/6861 , A61B2034/2055
摘要： An ingestible in-vivo gastrointestinal device constituted of: a power source; a processor and a memory; and a sensor, the processor, at least partially responsive to the sensor, to determine a location of the in-vivo gastrointestinal device as being in one of an esophagus, a stomach, a small intestine and a large intestine of a subject.
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公开(公告)号：US20190232079A1
公开(公告)日：2019-08-01
申请号：US16378098
申请日：2019-04-08
发明人： Sharon BEN-YEHUDA , Ram BEN-YEHUDA
IPC分类号： A61N5/06
CPC分类号： A61N5/0603 , A61N5/0613 , A61N5/0624 , A61N2005/0609 , A61N2005/0645 , A61N2005/0659 , A61N2005/0662
摘要： Provided is a swallowable capsule for providing phototherapy to a patient's gastrointestinal (GI) tract, the capsule including a power supply, one or more phototherapeutic light sources, a speed determination unit for calculating speed of movement of the capsule in the GI tract, and a controller unit for activating one or more of the one or more light sources for delivering a therapeutic illumination dose to a target site in the GI tract, based, at least in part, on a determined speed. Related apparatus and methods are also described.
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公开(公告)号：US10300296B2
公开(公告)日：2019-05-28
申请号：US14004691
申请日：2012-03-07
申请人： Sharon Ben-Yehuda , Ram Ben-Yehuda
发明人： Sharon Ben-Yehuda , Ram Ben-Yehuda
IPC分类号： A61N5/06
摘要： A swallowable capsule for providing phototherapy to a patient's gastrointestinal (GI) tract, the capsule including a power supply, one or more phototherapeutic light sources, a speed determination unit for calculating speed of movement of the capsule in the GI tract, and a controller unit for activating one or more of the one or more light sources for delivering a therapeutic illumination dose to a target site in the GI tract, based, at least in part, on a determined speed. Related apparatus and methods are also described.
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公开(公告)号：US20140081360A1
公开(公告)日：2014-03-20
申请号：US13623177
申请日：2012-09-20
申请人： Sharon BEN-YEHUDA , Ram BEN-YEHUDA
发明人： Sharon BEN-YEHUDA , Ram BEN-YEHUDA
IPC分类号： A61N5/06
CPC分类号： A61N5/0603 , A61B1/041 , A61N5/062 , A61N2005/0609 , A61N2005/0627
摘要： A method for providing phototherapy to a GI tract including using a capsule imager to scan at least a portion of a GI tract, estimating a location of a diseased portion of the GI tract, and based, at least in part, on the estimated location, using a phototherapy capsule to provide phototherapeutic light to the diseased portion.A swallowable capsule for providing phototherapy to a GI tract including a power supply, a camera unit, one or more light sources emitting in a range including visible and Near Infra Red (NIR), and a control unit for calculating an effective dose to the GI tract by controlling the one or more light sources, a communication unit for transmitting images from the camera unit to an out-of-body receiver and for receiving control commands from an out-of-body transmitter.Related apparatus and methods are also described.
摘要翻译： 一种用于向GI道提供光疗的方法，包括使用胶囊成像仪扫描GI道的至少一部分，估计胃肠道的病变部位的位置，并且至少部分地基于所估计的位置， 使用光疗胶囊向病变部分提供光治疗光。 一种用于向包括电源，照相机单元，在可见光和近红外（NIR）的范围内发射的一个或多个光源）的胃肠道提供光疗的可吞咽胶囊和用于计算GI的有效剂量的控制单元 通过控制一个或多个光源，通信单元，用于将图像从相机单元发送到体外接收器，并用于从体外发射器接收控制命令。 还描述了相关装置和方法。
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公开(公告)号：US20140005758A1
公开(公告)日：2014-01-02
申请号：US14004691
申请日：2012-03-07
申请人： Sharon Ben-Yehuda , Ram Ben-Yehuda
发明人： Sharon Ben-Yehuda , Ram Ben-Yehuda
IPC分类号： A61N5/06
CPC分类号： A61N5/0613 , A61N5/0603 , A61N5/0624 , A61N2005/0609 , A61N2005/0645 , A61N2005/0659 , A61N2005/0662
摘要： A swallowable capsule for providing phototherapy to a patient's gastrointestinal (GI) tract, the capsule including a power supply, one or more phototherapeutic light sources, a speed determination unit for calculating speed of movement of the capsule in the GI tract, and a controller unit for activating one or more of the one or more light sources for delivering a therapeutic illumination dose to a target site in the GI tract, based, at least in part, on a determined speed. Related apparatus and methods are also described.
摘要翻译： 一种用于向患者的胃肠道（GI）道提供光疗的吞咽胶囊，所述胶囊包括电源，一个或多个光治疗光源，用于计算胶囊在胃肠道中的移动速度的速度确定单元，以及控制器单元 用于激活所述一个或多个光源中的一个或多个，以至少部分地基于确定的速度将治疗照射剂量递送到胃肠道中的目标部位。 还描述了相关装置和方法。
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公开(公告)号：US20130013031A1
公开(公告)日：2013-01-10
申请号：US13634555
申请日：2011-03-17
申请人： Sharon Ben-Yehuda , Ram Ben-Yehuda
发明人： Sharon Ben-Yehuda , Ram Ben-Yehuda
IPC分类号： A61N5/06
CPC分类号： A61B5/065 , A61B5/073 , A61B5/14539 , A61B5/6861 , A61B2017/00035 , A61B2018/00494 , A61B2018/00708 , A61B2562/162 , A61N5/0603 , A61N2005/0609 , A61N2005/0659 , A61N2005/0662
摘要： The present invention provides a swallowable capsule suitable for providing phototherapy to a region of a patient's gastrointestinal (GI) tract, the capsule comprising one or more light sources emitting in the visible and/or NIR ranges and optical elements for shaping the light beam produced by said light sources, such that said light source(s) and said optical elements are capable of delivering an effective therapeutic dose to a target site within the GI tract. The present invention further provides a method for intraluminal phototherapy of the gastrointestinal tract using a swallowable capsule as described hereinabove.
摘要翻译： 本发明提供一种适用于向患者胃肠道（GI）区域的区域提供光疗的吞咽胶囊，所述胶囊包括在可见光和/或NIR范围内发射的一个或多个光源和用于成形由 所述光源，使得所述光源和所述光学元件能够向胃肠道内的靶位点递送有效的治疗剂量。 本发明还提供了如上所述的使用可吞咽胶囊的胃肠道腔内光疗法。
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公开(公告)号：US20120253204A1
公开(公告)日：2012-10-04
申请号：US13494199
申请日：2012-06-12
申请人： Sharon BEN-YEHUDA
发明人： Sharon BEN-YEHUDA
CPC分类号： A61N5/0603 , A61B1/00082 , A61B1/041 , A61B5/065 , A61B5/073 , A61N2005/0608
摘要： A phototherapeutic system for providing phototherapy to a patient's lower parts of a gastrointestinal (GI) tract, the phototherapeutic system including a capsule sized and shaped for insertion into the rectum, the capsule including one or more phototherapeutic light sources. A method for intra-luminal phototherapy of the lower parts of the gastrointestinal (GI) tract including inserting a phototherapeutic device including one or more phototherapeutic light sources into the rectum, activating the light sources, and providing light at a dose suitable for providing a phototherapeutic effect. Related apparatus and methods are also described.
摘要翻译： 一种光治疗系统，用于向胃肠道（GI）道的患者的下部提供光疗，所述光疗系统包括尺寸和形状适于插入直肠的胶囊，所述胶囊包括一个或多个光疗治疗光源。 一种胃肠道（GI）道下腔内光疗法的方法，包括将包括一种或多种光疗治疗光源的光治疗装置插入直肠内，激活光源，并以适合提供光治疗剂量的剂量提供光 影响。 还描述了相关装置和方法。
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公开(公告)号：US20220409919A1
公开(公告)日：2022-12-29
申请号：US17822017
申请日：2022-08-24
发明人： Sharon BEN-YEHUDA , Ram BEN-YEHUDA
IPC分类号： A61N5/06
摘要： A system and method for identifying a post cecum position of an ingestible, phototherapeutic capsule traveling through a gastrointestinal (GI) tract to prevent intestinal blockage and facilitating deployment of additional phototherapeutic capsules in accordance with patient needs. The system employs an ex-vitro beacon in wireless communication with the capsule. The ex-vitro beacon is deployed in the vicinity of the McBurney's point to direct a beacon signal toward the cecum to identify capsule passage into the large intestine less prone to blockage.
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公开(公告)号：US11464996B2
公开(公告)日：2022-10-11
申请号：US16378098
申请日：2019-04-08
发明人： Sharon Ben-Yehuda , Ram Ben-Yehuda
IPC分类号： A61N5/06
摘要： Provided is a swallowable capsule for providing phototherapy to a patient's gastrointestinal (GI) tract, the capsule including a power supply, one or more phototherapeutic light sources, a speed determination unit for calculating speed of movement of the capsule in the GI tract, and a controller unit for activating one or more of the one or more light sources for delivering a therapeutic illumination dose to a target site in the GI tract, based, at least in part, on a determined speed. Related apparatus and methods are also described.
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公开(公告)号：US20220152413A1
公开(公告)日：2022-05-19
申请号：US17436222
申请日：2020-03-03
发明人： Sharon BEN YEHUDA , Ram BEN YEHUDA
IPC分类号： A61N5/06
摘要： The present disclosure generally provides systems and methods for manipulating bacterial growth, abundance and diversity in biological sample. More particularly, the present invention relates to systems and methods for manipulating gut microbiota.
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